PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.D00818.1.p
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family B3
Protein Properties Length: 826aa    MW: 91065 Da    PI: 7.0438
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.D00818.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B356.93.9e-18310409198
                       EEEE-..-HHHHTT-EE--HHH.HTT..---..--SEEEEEETTS-EEEEEE....EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
                B3   1 ffkvltpsdvlksgrlvlpkkfaeeh..ggkkeesktltledesgrsWevkliy..rkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                       f+k+l+ sd+++ grlvlpk +ae++   +++ e++ + ++d +g++W +++++  +++s++yvl+ G     +  ++++gD+v+F++++  +
  Migut.D00818.1.p 310 FEKILSASDAGRIGRLVLPKACAEAYfpPINQSEGIPINIQDIKGKEWLFQFRFwpNNNSRMYVLE-GVTPCIQNMQVQAGDTVIFSRID-PG 400
                       99**************************777778999***************9989999999***9.********************887.88 PP

                       E..EEEEE- CS
                B3  90 felvvkvfr 98 
                       ++lv++ ++
  Migut.D00818.1.p 401 GQLVIGCRK 409
                       888888876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.05E-19307406IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.104.7E-27307410IPR015300DNA-binding pseudobarrel domain
CDDcd100175.40E-22308409No hitNo description
SMARTSM010193.4E-20310410IPR003340B3 DNA binding domain
PfamPF023624.3E-15310409IPR003340B3 DNA binding domain
PROSITE profilePS5086310.405310411IPR003340B3 DNA binding domain
PROSITE profilePS5105012.993536586IPR011124Zinc finger, CW-type
PfamPF074965.7E-11543583IPR011124Zinc finger, CW-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010030Biological Processpositive regulation of seed germination
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:2000034Biological Processregulation of seed maturation
GO:0005634Cellular Componentnucleus
GO:0005739Cellular Componentmitochondrion
GO:0003677Molecular FunctionDNA binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 826 aa     Download sequence    Send to blast
MGSQNCMNEA CRGTTSSEWK KGWTLKSGGF ATLCYTCGSA YENSIFCDKF HAEESGWREC  60
KICGKRVHCG CIVSRFLHEY MDYGGVGCMS CVKRLEIHSM KPIQIPSDIS NGTFLTNGIR  120
DTRPIIVENR IDDDKFSTER LLQLTKAIGT SDFSSAFQQF KQEESMLNKT RQTNKRLLNL  180
TQECSPSTFF KSDNNGRPKD ANESILPRPS LNFSLTPPIL PYSGGVVDGI ELSKNSPQQG  240
GLKARHILPK PPKPSPIELN KGSFSQARVA RPPAEGRGRN QLLPRYWPKI TDQELQQLSG  300
DLKSTIVPLF EKILSASDAG RIGRLVLPKA CAEAYFPPIN QSEGIPINIQ DIKGKEWLFQ  360
FRFWPNNNSR MYVLEGVTPC IQNMQVQAGD TVIFSRIDPG GQLVIGCRKA TNIFDLQDTQ  420
PLAITNGDSP GETSFSGVTD NNIFSNGGRT SDDSLQRHMS TTLSEKKKAR NIKNKRLLMH  480
NEDAMELRVT WEEAQELLRP TPNAEPTFVM IEDHLFEEFQ EPPIFGKRTI FTSRISGEQE  540
QLAQCDSCLK WRRLPVHALL SGKWTCSENT WDSKRCSCYA PEDINPRDLE SCISAYKDSK  600
KRKVSDKASN KEGEPSGLDA LATAAVLGDN NNNIVGAESS SVGAAATTRH PRHRPGCSCI  660
VCIQPPSGKG KHEPTCKCNV CLTVKRRFKT LMMRKKKRQS DREAELALQL KAASAAVEEE  720
DDKAGPAKNT GGGLEREDAE ERETAELDLN CDPHREEEAL LAEAAGISLT TLMNAVTSLP  780
LDMAYVGPPN GAVSTEEIDA TVAAVDGDLA EGNNRKDGPG GFNPI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6j9a_A2e-682884172131B3 domain-containing transcription repressor VAL1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1684695KRRFKTLMMRKK
2684697KRRFKTLMMRKKKR
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1. {ECO:0000269|PubMed:15894743, ECO:0000269|PubMed:17158584, ECO:0000269|PubMed:17267611}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.D00818.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012841792.10.0PREDICTED: B3 domain-containing transcription repressor VAL1-like
SwissprotQ8W4L50.0VAL1_ARATH; B3 domain-containing transcription repressor VAL1
TrEMBLA0A022S4000.0A0A022S400_ERYGU; Uncharacterized protein
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA14912365
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G30470.10.0high-level expression of sugar-inducible gene 2
Publications ? help Back to Top
  1. Jia H,McCarty DR,Suzuki M
    Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression.
    Plant Physiol., 2013. 163(3): p. 1293-305
    [PMID:24043445]
  2. Schneider A, et al.
    Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos.
    Plant J., 2016. 85(2): p. 305-19
    [PMID:26678037]
  3. Chhun T, et al.
    HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth.
    Plant Cell Physiol., 2016. 57(8): p. 1689-706
    [PMID:27335347]
  4. Qüesta JI,Song J,Geraldo N,An H,Dean C
    Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization.
    Science, 2016. 353(6298): p. 485-8
    [PMID:27471304]
  5. Yuan W, et al.
    A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis.
    Nat. Genet., 2016. 48(12): p. 1527-1534
    [PMID:27819666]
  6. Merini W, et al.
    The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development.
    Plant Physiol., 2017. 173(1): p. 627-641
    [PMID:27837089]
  7. Li C,Cui Y
    A DNA element that remembers winter.
    Nat. Genet., 2016. 48(12): p. 1451-1452
    [PMID:27898079]
  8. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]
  9. Sasnauskas G,Kauneckaite K,Siksnys V
    Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1.
    Nucleic Acids Res., 2018. 46(8): p. 4316-4324
    [PMID:29660015]
  10. Wu B, et al.
    Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana.
    Biochem. Biophys. Res. Commun., 2018. 501(2): p. 415-422
    [PMID:29733847]