PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.B01556.1.p
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family MYB
Protein Properties Length: 180aa    MW: 20802.5 Da    PI: 10.9429
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.B01556.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding44.63.3e-142974146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
   Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                      +g+W +eEde l++ v+++G+++W++I ++  + Rt+k+c++rw +
  Migut.B01556.1.p 29 KGPWKEEEDEVLINHVRKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 74
                      79*************************8887799**********87 PP
2Myb_DNA-binding45.61.7e-1485124344
                       SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
   Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                       ++++eE+   +++ +q+G++ W++Ia +++ gRt++++k++w
  Migut.B01556.1.p  85 KFSAEEERTVIELQAQFGNK-WARIATYLP-GRTDNDVKNFW 124
                       79******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.1E-212477IPR009057Homeodomain-like
PROSITE profilePS5129422.5062480IPR017930Myb domain
SuperFamilySSF466891.33E-2826124IPR009057Homeodomain-like
SMARTSM007174.6E-112878IPR001005SANT/Myb domain
CDDcd001677.23E-113176No hitNo description
PfamPF139211.9E-123282No hitNo description
Gene3DG3DSA:1.10.10.607.7E-1978130IPR009057Homeodomain-like
PROSITE profilePS5129417.91781132IPR017930Myb domain
SMARTSM007178.7E-1382130IPR001005SANT/Myb domain
PfamPF002495.2E-1385124IPR001005SANT/Myb domain
CDDcd001676.80E-1085124No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 180 aa     Download sequence    Send to blast
MESSRLCGIF SSRRRISRRH ENGDHDLRKG PWKEEEDEVL INHVRKYGPR DWSSIRSKGL  60
LQRTGKSCRL RWVNKLRPNL KNGVKFSAEE ERTVIELQAQ FGNKWARIAT YLPGRTDNDV  120
KNFWSSRQKR LARILQTSAP SSSSSSSNKS HKIIITNNAP TDPKEDEPPL VKPPSNFLHE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C3e-292613024126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.B01556.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012843921.11e-116PREDICTED: transcription factor MYB24
SwissprotA0A178VEK77e-71DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A022QVI51e-114A0A022QVI5_ERYGU; Uncharacterized protein
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA42072342
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.18e-72MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]