PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.14G045500.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family ARF
Protein Properties Length: 855aa    MW: 95712.8 Da    PI: 6.591
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.14G045500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B375.56e-24159260199
                          EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                          f+k+lt sd++++g +++ +++a+e+      +  ++ +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F  
  Manes.14G045500.1.p 159 FCKTLTASDTSTHGGFSVLRRHADEClppldmS-RQPPTQELMAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL- 246
                          99*****************************73.3334459************************************************. PP

                          -SSSEE..EEEEE-S CS
                   B3  85 dgrsefelvvkvfrk 99 
                           + +++el+v+v+r+
  Manes.14G045500.1.p 247 -RGENGELRVGVRRA 260
                          .449999*****996 PP
2Auxin_resp1201.8e-39285367183
           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          a+ha+st+++F+v+Y+Pr+s++eF+v+v+++++++k+++svGmRfkm+fe+e+++e+r++Gt+vg++d dp rW++SkWr+Lk
  Manes.14G045500.1.p 285 AWHAISTGTMFTVYYKPRTSPAEFIVPVDRYMESIKNNYSVGMRFKMRFEGEEAPEQRFTGTIVGIEDGDPKRWRESKWRCLK 367
                          89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.102.3E-41155274IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.75E-40156288IPR015300DNA-binding pseudobarrel domain
CDDcd100177.18E-21157259No hitNo description
SMARTSM010192.3E-23159261IPR003340B3 DNA binding domain
PfamPF023621.0E-21159260IPR003340B3 DNA binding domain
PROSITE profilePS5086311.914159261IPR003340B3 DNA binding domain
PfamPF065071.9E-36285367IPR010525Auxin response factor
PfamPF023094.9E-11719813IPR033389AUX/IAA domain
SuperFamilySSF542778.83E-13725805No hitNo description
PROSITE profilePS5174523.946728812IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 855 aa     Download sequence    Send to blast
MDSTEISTKG NGGNARGESF SSGHSEPNDH RNTMEGQKSH STRPISARDA ETALYTELWH  60
ACAGPLVTVP RERERVFYFP QGHIEQVEAS TNQLADQQMP VYDLPSKILC TVINVQLKAE  120
PDTDEVFAQV TLLPDPNQDE SAIDKEAPLP PPRFRVHSFC KTLTASDTST HGGFSVLRRH  180
ADECLPPLDM SRQPPTQELM AKDLHGNEWR FRHIFRGQPR RHLLQSGWSV FVSSKRLVAG  240
DAFIFLRGEN GELRVGVRRA MRQQGNVPSS VISSHSMHLG VLATAWHAIS TGTMFTVYYK  300
PRTSPAEFIV PVDRYMESIK NNYSVGMRFK MRFEGEEAPE QRFTGTIVGI EDGDPKRWRE  360
SKWRCLKVKW DETSTIPRPE RVSPWSIEPA LAPPALNPLP MPRPKRPRSN MVPSSPDSSV  420
LTREGSSKVT FDPQPPSGYL RVLQGQEFQT LRGNFAECNE SDTVEKSVVW PSSLEDEKVD  480
SVSASSRHGS DWILSGGPKP TCTDLLSGFG THVDSSHRFG AHIVDQTSTA ASRKLVLEQE  540
GKFNLLASPW SLMSSGLSLK LSDSNTKVPE KDCDMAFEAR GNIRCSAFNE YAMLNGHRVE  600
QSHGNWLMPP PPSHFDNHAH ARELGRKPIL VREHEIGKST DGKCKLFGIR LFNNPVMPES  660
AASHRNLVDD PMSCIHPQSH QLHVLDSDRS EQSKGSKMAD ENEYEKQLQA GLLHTSVNQS  720
KVQSVSTRSC TKVHKQGIVL GRSVDLTKFN NYDELVAELD RLFEFDGELM APKKNWLIVY  780
TDDEGDMMLV GDDPWQEFVG MVRKIFIYTR EEVQKMNPGT LNSKGDENLL DAEGMDAKEL  840
KCLPLPPVHN TEIC*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1785338918354Auxin response factor 1
4ldw_A1e-1785338918354Auxin response factor 1
4ldw_B1e-1785338918354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:15960614, ECO:0000269|PubMed:16176952, ECO:0000269|PubMed:16339187}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.14G045500.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF0220040.0KF022004.1 Jatropha curcas auxin response factor (ARF) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021592726.10.0auxin response factor 2A-like
SwissprotQ94JM30.0ARFB_ARATH; Auxin response factor 2
TrEMBLA0A251JQU50.0A0A251JQU5_MANES; Auxin response factor
STRINGcassava4.1_001542m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF32813366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Chao WS,Doğramaci M,Foley ME,Horvath DP,Anderson JV
    Selection and validation of endogenous reference genes for qRT-PCR analysis in leafy spurge (Euphorbia esula).
    PLoS ONE, 2012. 7(8): p. e42839
    [PMID:22916167]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Lyons R, et al.
    Fusarium oxysporum triggers tissue-specific transcriptional reprogramming in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0121902
    [PMID:25849296]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Zhao S,Zhang ML,Ma TL,Wang Y
    Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.
    Plant Cell, 2016. 28(12): p. 3005-3019
    [PMID:27895227]
  8. Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z
    ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis .
    J Integr Plant Biol, 2017. 59(1): p. 30-43
    [PMID:28074634]
  9. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  10. Sanz-Fernández M, et al.
    Screening Arabidopsis mutants in genes useful for phytoremediation.
    J. Hazard. Mater., 2017. 335: p. 143-151
    [PMID:28441590]
  11. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]
  12. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  13. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  14. Sarkar Das S, et al.
    Expression dynamics of miRNAs and their targets in seed germination conditions reveals miRNA-ta-siRNA crosstalk as regulator of seed germination.
    Sci Rep, 2018. 8(1): p. 1233
    [PMID:29352229]