PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.12G086200.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family C2H2
Protein Properties Length: 486aa    MW: 52954.6 Da    PI: 8.716
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.12G086200.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.74.4e-056080323
                         ETTTTEEESSHHHHHHHHHHT CS
              zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                         C++Cgk F r  nL+ H r H
  Manes.12G086200.1.p 60 CEICGKGFQRDQNLQLHRRGH 80
                         *******************88 PP
2zf-C2H213.40.00022134156123
                          EEETTTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                          +kC++C+k++  +s+ k H +t+
  Manes.12G086200.1.p 134 WKCEKCSKRYAVQSDWKAHSKTC 156
                          58*****************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.21E-65780No hitNo description
Gene3DG3DSA:3.30.160.604.2E-55780IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0765880IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.4895880IPR007087Zinc finger, C2H2
PROSITE patternPS0002806080IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.6E-4122155IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.21E-6129154No hitNo description
SMARTSM00355130134154IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 486 aa     Download sequence    Send to blast
MLEKMAEEAI LSNGFVENPV GGSNPPAVKK KRNLPGTPDP EAEVIALSPK TLMATNRFLC  60
EICGKGFQRD QNLQLHRRGH NLPWKLKQRT TKEVRKRVYV CPEKTCVHHH PSRALGDLTG  120
IKKHFCRKHG EKKWKCEKCS KRYAVQSDWK AHSKTCGTRE YKCDCGTLFS RRDSFITHRA  180
FCDALAEETA RLNAAANINS FAAAATSFNY HQLMGSPIGP NMAQHFSSIF KPISTNDQTM  240
DQTRSGLSLW VSQGSQGHHE VIGNNSIQEI HQLGSMGSSS GAIYCNPLVS SSNPSPSDHY  300
QLNWPVFGNK LSSSNAHEEL RSTSSLPLNN VKEATEVQLV SVPSLYSNQQ QSHQITSVAN  360
MSATALLLKA AQIGATSTDP SFLGSFGLKC SSNNQVHQEA GNKFCGLYGS NPISTGAINL  420
ACDMENSAGN DVSSLNELQI YPTAKRQKLQ ISDHQDGAAG GQTRDFLGVG AQQAICHPSS  480
INGWI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C4e-37130199372Zinc finger protein JACKDAW
5b3h_F4e-37130199372Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00125DAPTransfer from AT1G03840Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.12G086200.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021630010.10.0zinc finger protein MAGPIE-like
SwissprotQ9ZWA61e-161IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A2C9UUT00.0A0A2C9UUT0_MANES; Uncharacterized protein
STRINGcassava4.1_006502m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF46262951
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.11e-152C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]