PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.10G135400.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family MIKC_MADS
Protein Properties Length: 253aa    MW: 28762.7 Da    PI: 7.8762
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.10G135400.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF89.41.9e-28959151
                         S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
               SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                         krien+  rqvtfskRr+g+lKKA+EL +LCdaevaviifs+tgkl+e+ss
  Manes.10G135400.1.p  9 KRIENSNSRQVTFSKRRTGLLKKAQELAILCDAEVAVIIFSNTGKLFEFSS 59
                         79***********************************************96 PP
2K-box721.8e-24781726100
                K-box   6 gksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLr 95 
                            ++e++ +++ ++e+++Lk+ei +Lq +q  llG dL+ LslkeLq+LeqqL+++l  +++kK++ll+eq+e+++ +e+++  en++Lr
  Manes.10G135400.1.p  78 PARVEHKAEKQDSKEVDNLKEEIVKLQAKQLMLLGHDLTGLSLKELQHLEQQLNEGLLCVKEKKEHLLMEQLEQSRVQEQRAMLENETLR 167
                          455788889999****************************************************************************** PP

                K-box  96 kklee 100
                          +++ee
  Manes.10G135400.1.p 168 RQVEE 172
                          **987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006632.576161IPR002100Transcription factor, MADS-box
SMARTSM004321.0E-41160IPR002100Transcription factor, MADS-box
CDDcd002651.31E-42272No hitNo description
SuperFamilySSF554551.28E-32275IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-29323IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003194.1E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-292338IPR002100Transcription factor, MADS-box
PRINTSPR004041.7E-293859IPR002100Transcription factor, MADS-box
PfamPF014862.9E-1782170IPR002487Transcription factor, K-box
PROSITE profilePS5129713.58586176IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 253 aa     Download sequence    Send to blast
MGRGKIEIKR IENSNSRQVT FSKRRTGLLK KAQELAILCD AEVAVIIFSN TGKLFEFSSS  60
GMKRTLSRYK KCLDSTEPAR VEHKAEKQDS KEVDNLKEEI VKLQAKQLML LGHDLTGLSL  120
KELQHLEQQL NEGLLCVKEK KEHLLMEQLE QSRVQEQRAM LENETLRRQV EELRCFFPST  180
DHSVPTYHEY YSMERKHSLG SASADIACNC STEKGDSDTT LHLGLPTDRY RKRKAPEGES  240
HSNDSGSQLV LL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A2e-21169169MEF2C
5f28_B2e-21169169MEF2C
5f28_C2e-21169169MEF2C
5f28_D2e-21169169MEF2C
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro. {ECO:0000269|PubMed:10318690, ECO:0000269|PubMed:10662856, ECO:0000269|PubMed:12226488, ECO:0000269|PubMed:12743119, ECO:0000269|PubMed:14615187, ECO:0000269|PubMed:15084721, ECO:0000269|PubMed:15686521, ECO:0000269|PubMed:17521410, ECO:0000269|PubMed:18305206, ECO:0000269|PubMed:19269998, ECO:0000269|PubMed:19767455, ECO:0000269|PubMed:8953767}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.10G135400.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin (2,4-D). Feedback loop leading to direct down-regulation by itself. {ECO:0000269|PubMed:15686521}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021625470.10.0agamous-like MADS-box protein AGL15
SwissprotQ388475e-85AGL15_ARATH; Agamous-like MADS-box protein AGL15
TrEMBLA0A2C9V6080.0A0A2C9V608_MANES; Uncharacterized protein
STRINGcassava4.1_024653m1e-163(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF35823260
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G13790.12e-87AGAMOUS-like 15
Publications ? help Back to Top
  1. Zheng Q,Zheng Y,Perry SE
    Decreased GmAGL15 expression and reduced ethylene synthesis may contribute to reduced somatic embryogenesis in a poorly embryogenic cultivar of Glycine max.
    Plant Signal Behav, 2014.
    [PMID:23838957]
  2. Perry SE,Zheng Q,Zheng Y
    Transcriptome analysis indicates that GmAGAMOUS-Like 15 may enhance somatic embryogenesis by promoting a dedifferentiated state.
    Plant Signal Behav, 2016. 11(7): p. e1197463
    [PMID:27302197]
  3. Cosio C, et al.
    The class III peroxidase PRX17 is a direct target of the MADS-box transcription factor AGAMOUS-LIKE15 (AGL15) and participates in lignified tissue formation.
    New Phytol., 2017. 213(1): p. 250-263
    [PMID:27513887]
  4. Zheng Q,Zheng Y,Ji H,Burnie W,Perry SE
    Gene Regulation by the AGL15 Transcription Factor Reveals Hormone Interactions in Somatic Embryogenesis.
    Plant Physiol., 2016. 172(4): p. 2374-2387
    [PMID:27794101]
  5. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]