PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.08G119600.1.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

C2H2

Protein Properties

Length: 508aa MW: 55014.8 Da PI: 9.2232

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.08G119600.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.1	3.1e-05	91	113	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C++C+k F r nL+ H r H Manes.08G119600.1.p 91 FICEICNKGFQRDQNLQLHRRGH 113 89*******************88 PP
2	zf-C2H2	12.1	0.00061	167	189	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H +t+ Manes.08G119600.1.p 167 WKCDKCSKKYAVQSDWKAHNKTC 189 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.3E-5	90	113	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.48E-6	90	113	No hit	No description
PROSITE profile	PS50157	10.845	91	113	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.022	91	113	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	6.1E-5	91	113	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	93	113	IPR007087	Zinc finger, C2H2
SMART	SM00355	300	132	162	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	0.001	155	188	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.48E-6	162	187	No hit	No description
SMART	SM00355	170	167	187	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 508 aa Download sequence Send to blast
MSNITGEGGT FSSGNTTAAV GEADVQQQEL LINHLNSIAS TTVATSTTNG STAQQHQPST 60 VKKKRNLPGN PDPSAEVIAL SPKTLLATNR FICEICNKGF QRDQNLQLHR RGHNLPWKLR 120 QRTSTEIRKR VYICPELSCV HHNPARALGD LTGIKKHFCR KHGEKKWKCD KCSKKYAVQS 180 DWKAHNKTCG TKEYKCDCGT IFSRRDSFIT HRAFCDALTE ENNKANQGLV PKTETNLQSQ 240 VPNLISIPIN NNQDQPMIMS NLSNLDTRIP LSLPHELMPI PTKPSGAMFS SGTTSLFGGG 300 RSLSNCSSSF QLSANSSTVF EGNAHISAGS VSMSATALLQ KAAQMGATAS PTTHKSFVAG 360 MASSTFGPMQ NSNDQSQVTA GGNGGFINQF FNANGGIENP AANDVGLING VLDQTSGLFK 420 NIEQKTSNDK SFFHGVNSSP GLISSGLTRF SGDVMTVDFL GVGGSRQRNL HEHHKQEMEF 480 RGIVHPRIHQ GLGQFEQTAL EKPMWDV*

Sequence ? help Back to Top

Protein Sequence Length: 508 aa Download sequence Send to blast

MSNITGEGGT FSSGNTTAAV GEADVQQQEL LINHLNSIAS TTVATSTTNG STAQQHQPST  60
VKKKRNLPGN PDPSAEVIAL SPKTLLATNR FICEICNKGF QRDQNLQLHR RGHNLPWKLR  120
QRTSTEIRKR VYICPELSCV HHNPARALGD LTGIKKHFCR KHGEKKWKCD KCSKKYAVQS  180
DWKAHNKTCG TKEYKCDCGT IFSRRDSFIT HRAFCDALTE ENNKANQGLV PKTETNLQSQ  240
VPNLISIPIN NNQDQPMIMS NLSNLDTRIP LSLPHELMPI PTKPSGAMFS SGTTSLFGGG  300
RSLSNCSSSF QLSANSSTVF EGNAHISAGS VSMSATALLQ KAAQMGATAS PTTHKSFVAG  360
MASSTFGPMQ NSNDQSQVTA GGNGGFINQF FNANGGIENP AANDVGLING VLDQTSGLFK  420
NIEQKTSNDK SFFHGVNSSP GLISSGLTRF SGDVMTVDFL GVGGSRQRNL HEHHKQEMEF  480
RGIVHPRIHQ GLGQFEQTAL EKPMWDV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	8e-34	163	224	3	64	Zinc finger protein JACKDAW
5b3h_F	8e-34	163	224	3	64	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.08G119600.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681805	2e-39	LN681805.1 Cucumis melo genomic scaffold, anchoredscaffold00067.
GenBank	LN713255	2e-39	LN713255.1 Cucumis melo genomic chromosome, chr_1.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021619689.1	0.0	protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-114	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A2C9VFN1	0.0	A0A2C9VFN1_MANES; Uncharacterized protein
STRING	cassava4.1_005941m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-102	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Manes.08G119600.1.p

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]