PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Manes.05G065500.1.p

Organism

Manihot esculenta

Taxonomic ID

3983

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

C2H2

Protein Properties

Length: 573aa MW: 62585.8 Da PI: 8.6141

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.05G065500.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17	1.7e-05	88	110	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Manes.05G065500.1.p 88 FVCEICNKGFQRDQNLQLHRRGH 110 89*******************88 PP
2	zf-C2H2	15.4	5.3e-05	164	186	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ Manes.05G065500.1.p 164 WKCDKCSKKYAVQSDWKAHQKTC 186 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.9E-5	87	110	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.66E-8	87	110	No hit	No description
PROSITE profile	PS50157	10.949	88	110	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	88	110	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	90	110	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	129	159	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.8E-5	152	185	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.66E-8	159	185	No hit	No description
SMART	SM00355	94	164	184	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 573 aa Download sequence Send to blast
MSNITGDEGS FSSGNTGEEV QQLQEKQQLQ LQNHFHGSNS GATNSNDSTS QQQQQQPIKK 60 KRNLPGTPDP NAEVIALSPT TLMATNRFVC EICNKGFQRD QNLQLHRRGH NLPWKLRQRT 120 TTEVKKRVYI CPEPTCVHHN PARALGDLTG IKKHFSRKHG EKKWKCDKCS KKYAVQSDWK 180 AHQKTCGTRE YKCDCGTIFS RRDSFITHRA FCDALAEENN KVNQGLMSNM GSNLQTQMPD 240 IMSSMPLTST NANSTSIGIS DFNSFDPKNP LKSLPQELVP IPFKSMNMAA GGGMFSSSSG 300 TLFGGPRSIS SASSSLQLSS NSSSGYSYLQ DGKNGCQISG SAHMSATALL QKAAQMGATA 360 SNSINSPMMQ KSFASSMAGP DQISSIRPPS YVGVQQHGAT SYDHFPSQPE QTSMVGINAG 420 GFNNNNQHLQ KGPQEMSQFF ETATGSSGMN DMGMFSTMFM GTEQNPGFMK SMEHEDSGSS 480 SLIHGRSGME RNLSGPSRFG GSGGEGGDRM TRDFMGIGGS RTGNLLDHQQ QQQQQSLEME 540 AISQQHRMPM MNHFQQQLSL GESALEKRMW DV*

Sequence ? help Back to Top

Protein Sequence Length: 573 aa Download sequence Send to blast

MSNITGDEGS FSSGNTGEEV QQLQEKQQLQ LQNHFHGSNS GATNSNDSTS QQQQQQPIKK  60
KRNLPGTPDP NAEVIALSPT TLMATNRFVC EICNKGFQRD QNLQLHRRGH NLPWKLRQRT  120
TTEVKKRVYI CPEPTCVHHN PARALGDLTG IKKHFSRKHG EKKWKCDKCS KKYAVQSDWK  180
AHQKTCGTRE YKCDCGTIFS RRDSFITHRA FCDALAEENN KVNQGLMSNM GSNLQTQMPD  240
IMSSMPLTST NANSTSIGIS DFNSFDPKNP LKSLPQELVP IPFKSMNMAA GGGMFSSSSG  300
TLFGGPRSIS SASSSLQLSS NSSSGYSYLQ DGKNGCQISG SAHMSATALL QKAAQMGATA  360
SNSINSPMMQ KSFASSMAGP DQISSIRPPS YVGVQQHGAT SYDHFPSQPE QTSMVGINAG  420
GFNNNNQHLQ KGPQEMSQFF ETATGSSGMN DMGMFSTMFM GTEQNPGFMK SMEHEDSGSS  480
SLIHGRSGME RNLSGPSRFG GSGGEGGDRM TRDFMGIGGS RTGNLLDHQQ QQQQQSLEME  540
AISQQHRMPM MNHFQQQLSL GESALEKRMW DV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-33	160	233	3	71	Zinc finger protein JACKDAW
5b3h_F	2e-33	160	233	3	71	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.05G065500.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021612449.1	0.0	protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-114	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A2C9VTY7	0.0	A0A2C9VTY7_MANES; Uncharacterized protein
STRING	cassava4.1_030413m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	4e-99	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Manes.05G065500.1.p

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]