PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000825712

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

ERF

Protein Properties

Length: 192aa MW: 21450.6 Da PI: 8.1095

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000825712	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	40	1e-12	2	44	7	52
AP2 7 rwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkk 52 +++++ grW A+I g +k+ +lg+fgt eeAa+a++ a+ k MDP0000825712 2 TRHHQHGRWQARIGR----GtGNKHLYLGTFGTQEEAAEAYDMAAIK 44 57999*****999....4447*******************976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	12.668	1	59	IPR001471	AP2/ERF domain
SMART	SM00380	1.0E-10	2	63	IPR001471	AP2/ERF domain
Pfam	PF00847	2.7E-8	3	44	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	5.7E-11	3	45	IPR001471	AP2/ERF domain
CDD	cd00018	2.35E-15	3	53	No hit	No description
SuperFamily	SSF54171	1.44E-11	3	53	IPR016177	DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 192 aa Download sequence Send to blast
MTRHHQHGRW QARIGRGTGN KHLYLGTFGT QEEAAEAYDM AAIKCPRTTP TSNPTMDYQT 60 ADSEHVLKRS RPFEVTDEAN NLPVNMLPVA YPNQSHGQSS YSSNDLPKSV VMTLRPGSTV 120 KSMDFHPMQQ ILLLVGTNMG DVMLYELPSH EKIAIKNFKV WDLGACSAAL QVWLLIFCKI 180 KLMQTFNVEL A*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription corepressor of Zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling. {ECO:0000269\|PubMed:25035403}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028955356.1	1e-143	topless-related protein 4-like isoform X6
Swissprot	Q27GK7	4e-48	TPR4_ARATH; Topless-related protein 4
TrEMBL	A0A251NGD3	1e-72	A0A251NGD3_PRUPE; Uncharacterized protein
TrEMBL	A0A314Z9V5	5e-72	A0A314Z9V5_PRUYE; Topless-related protein 4-like isoform X2
STRING	XP_008355021.1	1e-111	(Malus domestica)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37750.1	4e-22	AP2 family protein

Link Out ? help Back to Top
Phytozome	MDP0000825712

Publications ? help Back to Top
Yang ZN,Ye XR,Molina J,Roose ML,Mirkov TE Sequence analysis of a 282-kilobase region surrounding the citrus Tristeza virus resistance gene (Ctv) locus in Poncirus trifoliata L. Raf. Plant Physiol., 2003. 131(2): p. 482-92 [PMID:12586873] Long JA,Ohno C,Smith ZR,Meyerowitz EM TOPLESS regulates apical embryonic fate in Arabidopsis. Science, 2006. 312(5779): p. 1520-3 [PMID:16763149] Tao Q, et al. The TIE1 transcriptional repressor links TCP transcription factors with TOPLESS/TOPLESS-RELATED corepressors and modulates leaf development in Arabidopsis. Plant Cell, 2013. 25(2): p. 421-37 [PMID:23444332] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Ke J, et al. Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors. Sci Adv, 2015. 1(6): p. e1500107 [PMID:26601214]