PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000736994
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MYB
Protein Properties Length: 338aa    MW: 38305.7 Da    PI: 6.1838
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000736994genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding46.39.8e-153077148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g W++eEde+l ++    G g+W+ Iar  g+ R++k+c++rw +yl
    MDP0000736994 30 KGLWSPEEDEKLMRYMLTSGQGCWSDIARNAGLQRCGKSCRLRWINYL 77
                     678*******************************************97 PP
2Myb_DNA-binding506.7e-1683126146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg+++++E+el+++ +  lG++ W+ Ia++++ gRt++++k++w++
    MDP0000736994  83 RGAFSPQEEELIIHFHSILGNR-WSQIAARLP-GRTDNEIKNFWNS 126
                      89********************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.1572577IPR017930Myb domain
SuperFamilySSF466893.55E-2828124IPR009057Homeodomain-like
SMARTSM007173.7E-112979IPR001005SANT/Myb domain
PfamPF002492.5E-133077IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.2E-233184IPR009057Homeodomain-like
CDDcd001671.42E-93377No hitNo description
PROSITE profilePS5129425.14478132IPR017930Myb domain
SMARTSM007172.4E-1582130IPR001005SANT/Myb domain
PfamPF002491.1E-1483126IPR001005SANT/Myb domain
CDDcd001675.60E-1185125No hitNo description
Gene3DG3DSA:1.10.10.601.6E-2585133IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000652Biological Processregulation of secondary cell wall biogenesis
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 338 aa     Download sequence    Send to blast
MRKPESMGKD DVGGAKTISK KKMMMNKLRK GLWSPEEDEK LMRYMLTSGQ GCWSDIARNA  60
GLQRCGKSCR LRWINYLRPD LKRGAFSPQE EELIIHFHSI LGNRWSQIAA RLPGRTDNEI  120
KNFWNSALKK RLKNNNMSTS TSSPNDSDSL DPRDHVVGGT FLPMQDHDMM TMCNMDSSSS  180
SSTSMQAMAV NSNTLFNPFY MLDNRYDKAH ADDIVLNPTC FPHLPNLEVN QEHYGDYGNL  240
EGGHKMGLEG DLFLPPLESR SIENNLNGQL VXDNISKKSI SNYHFHNSCF NNTEIGFKVY  300
EEEDMFGYGN NVGQGENVRV GEWDFDGFMQ DISSFLS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C1e-262113218128MYB TRANSFORMING PROTEIN
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed specifically in fiber and vessel cells that are undergoing secondary wall thickening in floral stems. Expressed in vessels but not in xylary fibers in the developing secondary xylem of roots. {ECO:0000269|PubMed:19808805}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1 and its close homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and NAC030/VND7. Is required for functional expression of a number of secondary wall-associated transcription factors and secondary wall biosynthetic genes involved in cellulose, xylan and lignin synthesis. Functions redundantly with MYB46 in the transcriptional regulatory cascade leading to secondary wall formation in fibers and vessels (PubMed:19808805). Transcription activator that binds to the DNA consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary wall MYB-responsive element (SMRE). Regulates directly numerous transcription factors and a number of genes involved in secondary wall biosynthesis that contain SMRE elements in their promoters (PubMed:22197883). {ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:22197883}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00336DAPTransfer from AT3G08500Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY9703573e-80AY970357.1 Prunus salicina clone PSX08 microsatellite sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008344632.20.0transcription factor MYB83-like
SwissprotQ9C6U12e-80MYB83_ARATH; Transcription factor MYB83
TrEMBLA0A498KDD40.0A0A498KDD4_MALDO; Uncharacterized protein
STRINGXP_008344632.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF77434128
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G08500.12e-73myb domain protein 83
Publications ? help Back to Top
  1. Vargas L, et al.
    Improving total saccharification yield of Arabidopsis plants by vessel-specific complementation of caffeoyl shikimate esterase (cse) mutants.
    Biotechnol Biofuels, 2016. 9: p. 139
    [PMID:27390589]
  2. Piya S,Kihm C,Rice JH,Baum TJ,Hewezi T
    Cooperative Regulatory Functions of miR858 and MYB83 during Cyst Nematode Parasitism.
    Plant Physiol., 2017. 174(3): p. 1897-1912
    [PMID:28512179]