PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000607777
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HD-ZIP
Protein Properties Length: 310aa    MW: 34855.2 Da    PI: 8.0084
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000607777genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.55.4e-19144198256
                    T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
       Homeobox   2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                    rk+ +++k+q  +Lee F+++++++ +++  LAk+lgL  rqV vWFqNrRa+ k
  MDP0000607777 144 RKKLRLSKDQSGILEESFKEHNTLNPKQKLALAKQLGLRPRQVEVWFQNRRARTK 198
                    788899***********************************************98 PP
2HD-ZIP_I/II123.87.9e-40144232189
    HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLre 89 
                    +kk+rlsk+q+ +LEesF+e+++L+p++K +la++Lgl+prqv+vWFqnrRARtk+k +E+d+e+Lkr++++ +e+n+rL+kev+eLr+
  MDP0000607777 144 RKKLRLSKDQSGILEESFKEHNTLNPKQKLALAKQLGLRPRQVEVWFQNRRARTKLKXTEVDCEFLKRCCENXTERNRRLQKEVQELRA 232
                    69*************************************************************************************94 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF046187.6E-282118IPR006712HD-ZIP protein, N-terminal
SuperFamilySSF466895.56E-18134199IPR009057Homeodomain-like
PROSITE profilePS5007117.313140200IPR001356Homeobox domain
SMARTSM003892.7E-16142204IPR001356Homeobox domain
PfamPF000462.0E-16144198IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.604.9E-18144198IPR009057Homeodomain-like
CDDcd000862.16E-15144198No hitNo description
PRINTSPR000312.2E-5171180IPR000047Helix-turn-helix motif
PROSITE patternPS000270175198IPR017970Homeobox, conserved site
PRINTSPR000312.2E-5180196IPR000047Helix-turn-helix motif
PfamPF021838.0E-7200233IPR003106Leucine zipper, homeobox-associated
SMARTSM003409.0E-22200243IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 310 aa     Download sequence    Send to blast
MMVEREDLGL GLSLNFPHTH NNQSSSRFQL NLMPSLLPTS AAASSSPSGF LPQMPLWNNP  60
LPSSDLNSNS ETCRAGPRSF LRGIDVNQLP PTGDCEEAGV SSPNSTVSTV SGKRSERDIN  120
GEDLDLERDC SRGLSDEEDG ETSRKKLRLS KDQSGILEES FKEHNTLNPK QKLALAKQLG  180
LRPRQVEVWF QNRRARTKLK XTEVDCEFLK RCCENXTERN RRLQKEVQEL RALXFSPQFY  240
MQMXXPITLT MCPSCERVGV XXNSXXXAAD XWXHSQMGPV QRXPLPIKPW ASAATVPHRP  300
LPFDIFHPR*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1142148SRKKLRL
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.100232e-62bud| fruit| leaf| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Predominantly expressed in leaves and stems. {ECO:0000269|PubMed:8106086}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the negative regulation of cell elongation and specific cell proliferation processes such as lateral root formation and secondary growth of the vascular system. Acts as mediator of the red/far-red light effects on leaf cell expansion in the shading response. Binds to the DNA sequence 5'-CAAT[GC]ATTG-3'. Negatively regulates its own expression. {ECO:0000269|PubMed:10477292, ECO:0000269|PubMed:11260495, ECO:0000269|PubMed:8449400}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Rapidly and strongly induced by lowering the ratio of red to far-red light. {ECO:0000269|PubMed:8106086}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008367712.20.0homeobox-leucine zipper protein HAT4-like
SwissprotQ054666e-92HAT4_ARATH; Homeobox-leucine zipper protein HAT4
TrEMBLA0A498JUL30.0A0A498JUL3_MALDO; Uncharacterized protein
STRINGXP_008361167.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF123934105
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16780.11e-71homeobox protein 2
Publications ? help Back to Top
  1. Carabelli M,Turchi L,Ruzza V,Morelli G,Ruberti I
    Homeodomain-Leucine Zipper II family of transcription factors to the limelight: central regulators of plant development.
    Plant Signal Behav, 2014.
    [PMID:23838958]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Francisco M, et al.
    Genome Wide Association Mapping in Arabidopsis thaliana Identifies Novel Genes Involved in Linking Allyl Glucosinolate to Altered Biomass and Defense.
    Front Plant Sci, 2016. 7: p. 1010
    [PMID:27462337]
  4. Müller-Moulé P, et al.
    YUCCA auxin biosynthetic genes are required for Arabidopsis shade avoidance.
    PeerJ, 2016. 4: p. e2574
    [PMID:27761349]
  5. Ivarson E, et al.
    Effects of Overexpression of WRI1 and Hemoglobin Genes on the Seed Oil Content of Lepidium campestre.
    Front Plant Sci, 2016. 7: p. 2032
    [PMID:28119714]
  6. Kasulin L, et al.
    A single haplotype hyposensitive to light and requiring strong vernalization dominates Arabidopsis thaliana populations in Patagonia, Argentina.
    Mol. Ecol., 2017. 26(13): p. 3389-3404
    [PMID:28316114]
  7. Singh M,Gupta A,Singh D,Khurana JP,Laxmi A
    Arabidopsis RSS1 Mediates Cross-Talk Between Glucose and Light Signaling During Hypocotyl Elongation Growth.
    Sci Rep, 2017. 7(1): p. 16101
    [PMID:29170398]