PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000601705

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 381aa MW: 43231.6 Da PI: 7.752

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000601705	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.4	2.6e-05	186	205	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ MDP0000601705 186 FSCPVCYKTFNRYNNMQMHM 205 89*****************9 PP
2	zf-C2H2	14.4	0.00011	270	292	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk F + + ++H +++ MDP0000601705 270 FMCRKCGKAFAVRGDWRTHEKNC 292 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	7.46E-5	177	208	No hit	No description
PROSITE profile	PS50157	9.743	186	213	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.45	186	208	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.7E-6	186	205	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	188	208	IPR007087	Zinc finger, C2H2
SMART	SM00355	230	232	265	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	1.46E-5	252	290	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.0E-4	266	290	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	49	270	290	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.808	270	290	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 381 aa Download sequence Send to blast
MADYPYSSNF FSGLLKFNPL HRHHEPPPQP PPHPSQPPPP YAHNFFLNQT HSFYFLTDQQ 60 NLNTRPPSPP LREALPLLSR LSPTNQHXDP EDQQQQHLHE DHHHFKDQQD EEDGDGXDDE 120 SVTVALHIGL PNPSDSEMAS VLSAAANSSS SEMSNDSAGY PMTCRLNKGQ YWIPTPSQIL 180 IGPTQFSCPV CYKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTGMLRL PCYCCTPGCR 240 NNIDXPRAKP LKDFRTLQTH YKRKHGIKHF MCRKCGKAFA VRGDWRTHEK NCGKLWFCIC 300 GSDFKHKRSL KDHIKAFGNG HAAYGFNGFE EEDEPASEVE QDNENAKLMP QALLGVYFAD 360 SLKXKVKMVQ PCLQSRLGVP *

Sequence ? help Back to Top

Protein Sequence Length: 381 aa Download sequence Send to blast

MADYPYSSNF FSGLLKFNPL HRHHEPPPQP PPHPSQPPPP YAHNFFLNQT HSFYFLTDQQ  60
NLNTRPPSPP LREALPLLSR LSPTNQHXDP EDQQQQHLHE DHHHFKDQQD EEDGDGXDDE  120
SVTVALHIGL PNPSDSEMAS VLSAAANSSS SEMSNDSAGY PMTCRLNKGQ YWIPTPSQIL  180
IGPTQFSCPV CYKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTGMLRL PCYCCTPGCR  240
NNIDXPRAKP LKDFRTLQTH YKRKHGIKHF MCRKCGKAFA VRGDWRTHEK NCGKLWFCIC  300
GSDFKHKRSL KDHIKAFGNG HAAYGFNGFE EEDEPASEVE QDNENAKLMP QALLGVYFAD  360
SLKXKVKMVQ PCLQSRLGVP *

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.16437	0.0	bud\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in developing carpels (PubMed:17600712). Expressed in the shoot apical meristem and the replum (PubMed:25039392). {ECO:0000269\|PubMed:17600712}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001315961.1	0.0	zinc finger protein WIP2-like
Swissprot	Q9SVY1	1e-136	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	D9ZIS7	0.0	D9ZIS7_MALDO; C2H2L domain class transcription factor
STRING	XP_008392177.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF170	34	289

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-130	C2H2 family protein

Link Out ? help Back to Top
Phytozome	MDP0000601705

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]