PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000564897
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HD-ZIP
Protein Properties Length: 330aa    MW: 37214 Da    PI: 4.9739
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000564897genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.45.9e-1957110356
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
       Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                    k+++++ eq+++Le+ Fe ++++  e++ +LA++lgL+ rqV vWFqNrRa++k
  MDP0000564897  57 KKRRLSVEQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWK 110
                    56689************************************************9 PP
2HD-ZIP_I/II130.66.1e-4256148193
    HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 
                    ekkrrls eqvk+LE++Fe e+kLeperKv+la+eLglqprqvavWFqnrRAR+ktkqlE+dy++Lk++yd++k++ ++L++++e+L +e+k+
  MDP0000564897  56 EKKRRLSVEQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWKTKQLERDYSVLKANYDTVKRNYDTLQHDNEALLKEIKQ 148
                    69**************************************************************************************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.15E-1941114IPR009057Homeodomain-like
PROSITE profilePS5007117.57252112IPR001356Homeobox domain
SMARTSM003896.1E-1855116IPR001356Homeobox domain
CDDcd000866.21E-1657113No hitNo description
PfamPF000463.8E-1657110IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.605.2E-2059119IPR009057Homeodomain-like
PRINTSPR000319.5E-68392IPR000047Helix-turn-helix motif
PROSITE patternPS00027087110IPR017970Homeobox, conserved site
PRINTSPR000319.5E-692108IPR000047Helix-turn-helix motif
PfamPF021833.6E-16112154IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 330 aa     Download sequence    Send to blast
MKRLGSSDSF GAMISICPTT EEHSPRNNHV YSREFQSMLD GLDEEGCVEE AGHVSEKKRR  60
LSVEQVKALE KNFEVENKLE PERKVKLAQE LGLQPRQVAV WFQNRRARWK TKQLERDYSV  120
LKANYDTVKR NYDTLQHDNE ALLKEIKQLK AKLQEDNAAS KNPTVKEEQL LGKDQSYKVV  180
QERSQSPPPP PGSSVPETEC NELNFESFNN TSGVLEAVSL FPDFKDGSSD SDSSAILNED  240
NSPNLTMSSS GILQNHQLIK XPASTSLKFN CSSSSSPSSS SMNCFPFQKS YQPLVKVEEH  300
NFFSSEEACS FFSDEQAPSL QWYCPDQWS*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1104112RRARWKTKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.67430.0bud| cell culture| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:16055682}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'-CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00271DAPTransfer from AT2G22430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. Self expression regulation. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416, ECO:0000269|PubMed:16055682}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB6219081e-110AB621908.1 Pyrus pyrifolia mRNA, microsatellite: TsuENH184.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008338560.20.0homeobox-leucine zipper protein ATHB-6-like isoform X1
SwissprotP466682e-76ATHB6_ARATH; Homeobox-leucine zipper protein ATHB-6
TrEMBLA0A498I2730.0A0A498I273_MALDO; Uncharacterized protein
STRINGXP_008338560.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18683489
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22430.11e-66homeobox protein 6
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]