PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000427227
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HD-ZIP
Protein Properties Length: 204aa    MW: 23831.6 Da    PI: 9.2297
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000427227genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox65.86e-2179132356
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
       Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                    k++++t++q++ Le+ Fe ++++  e++++LAkklgL+ rqV vWFqNrRa++k
  MDP0000427227  79 KKRRLTSDQVHMLEKSFETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARWK 132
                    56789************************************************9 PP
2HD-ZIP_I/II136.31e-4378168191
    HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 
                    ekkrrl+++qv++LE+sFe+e+kLeperK++la++LglqprqvavWFqnrRAR+ktkqlE+dy+ Lk++yd+l ++ +++ ke+++L+++l
  MDP0000427227  78 EKKRRLTSDQVHMLEKSFETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARWKTKQLERDYDLLKSSYDTLLSDYDSILKENQKLKSQL 168
                    69**************************************************************************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007118.0174134IPR001356Homeobox domain
SMARTSM003894.2E-2077138IPR001356Homeobox domain
CDDcd000863.08E-1779135No hitNo description
SuperFamilySSF466895.13E-2079145IPR009057Homeodomain-like
PfamPF000463.1E-1879132IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.5E-2280141IPR009057Homeodomain-like
PRINTSPR000312.5E-6105114IPR000047Helix-turn-helix motif
PROSITE patternPS000270109132IPR017970Homeobox, conserved site
PRINTSPR000312.5E-6114130IPR000047Helix-turn-helix motif
PfamPF021831.3E-14134168IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 204 aa     Download sequence    Send to blast
MMEPGRFFFE PSPSSAVCQQ GGGGNMLFLG NPDHXFRGXR SMMGLMDQES SRRRPFFSSS  60
SSQDELFDEE YYDEQLPEKK RRLTSDQVHM LEKSFETENK LEPERKTQLA KKLGLQPRQV  120
AVWFQNRRAR WKTKQLERDY DLLKSSYDTL LSDYDSILKE NQKLKSQLLV AWNIALAMNA  180
FSLYFILYTK FAKYISNQNV NVP*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1126134RRARWKTKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.115230.0cell culture| fruit| leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16055682}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription activator involved in leaf development. Binds to the DNA sequence 5'-CAAT[AT]ATTG-3'. {ECO:0000269|PubMed:8535134}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJQ6787880.0JQ678788.1 Malus x domestica HB-1 (hb-1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001315708.11e-106homeobox-leucine zipper protein HAT5-like
SwissprotQ022833e-64HAT5_ARATH; Homeobox-leucine zipper protein HAT5
TrEMBLA0A3G6IIH81e-147A0A3G6IIH8_MALDO; HB1
STRINGXP_008348031.11e-118(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF112833039
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01470.12e-42homeobox 1
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Ribone PA,Capella M,Arce AL,Chan RL
    A uORF Represses the Transcription Factor AtHB1 in Aerial Tissues to Avoid a Deleterious Phenotype.
    Plant Physiol., 2017. 175(3): p. 1238-1253
    [PMID:28956754]