PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000403797

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 358aa MW: 40436.3 Da PI: 7.2193

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000403797	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.8	8.4e-05	196	215	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ MDP0000403797 196 FSCPLCFKTFNRYNNMQMHM 215 89*****************9 PP
2	zf-C2H2	14.5	0.0001	280	302	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk F + + ++H +++ MDP0000403797 280 FMCRKCGKAFAVRGDWRTHEKNC 302 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00355	0.61	196	218	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.66	196	223	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.0E-5	196	215	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	198	218	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.82E-6	262	300	No hit	No description
Gene3D	G3DSA:3.30.160.60	9.6E-6	276	300	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	49	280	300	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.808	280	300	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 358 aa Download sequence Send to blast
MTDPYPNYFN NGWFNINXVH HFSSTSTPSS XNPYNYHPPN YGDYHNFCSS NNLINNINNT 60 LFTNHHHQSS SPPSPPLREA LPLLSQSPSR NHHHEDMQES AAADDHQSFL SSSRSDDIVD 120 HQEEDDETVT VALHLGLPSR TLSSADLISR LSSPEIPSDK EADVTVASAG FASNRLNKGQ 180 YWIPTPAQIL IGPTQFSCPL CFKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTAMLRL 240 PCYCCAPGCR NNIDHPRAKP LKDFRTLQTH YKRKHGIKPF MCRKCGKAFA VRGDWRTHEK 300 NCGKLWYCTC GSDFKHKRSL KDHIKAFGQG HAAYGIDCFE EEDDVASEIE ENDSSSH*

Sequence ? help Back to Top

Protein Sequence Length: 358 aa Download sequence Send to blast

MTDPYPNYFN NGWFNINXVH HFSSTSTPSS XNPYNYHPPN YGDYHNFCSS NNLINNINNT  60
LFTNHHHQSS SPPSPPLREA LPLLSQSPSR NHHHEDMQES AAADDHQSFL SSSRSDDIVD  120
HQEEDDETVT VALHLGLPSR TLSSADLISR LSSPEIPSDK EADVTVASAG FASNRLNKGQ  180
YWIPTPAQIL IGPTQFSCPL CFKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTAMLRL  240
PCYCCAPGCR NNIDHPRAKP LKDFRTLQTH YKRKHGIKPF MCRKCGKAFA VRGDWRTHEK  300
NCGKLWYCTC GSDFKHKRSL KDHIKAFGQG HAAYGIDCFE EEDDVASEIE ENDSSSH*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in developing carpels (PubMed:17600712). Expressed in the shoot apical meristem and the replum (PubMed:25039392). {ECO:0000269\|PubMed:17600712}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008352513.2	0.0	zinc finger protein WIP2-like
Swissprot	Q9SVY1	1e-134	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A498K948	0.0	A0A498K948_MALDO; Uncharacterized protein
STRING	XP_008352513.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF170	34	289

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-124	C2H2 family protein

Link Out ? help Back to Top
Phytozome	MDP0000403797

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]