PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000362243
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family C2H2
Protein Properties Length: 287aa    MW: 31137.4 Da    PI: 4.4807
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000362243genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.70.00019260283123
                    EEETTTTEEESSHHHHHHHHHH.T CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirt.H 23 
                    ++C+ C+ksF++   L +H +  H
  MDP0000362243 260 HSCKTCSKSFNSDGALSSHNKAkH 283
                    79*****************88766 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5015710.637260287IPR007087Zinc finger, C2H2
PROSITE patternPS000280262283IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009294Biological ProcessDNA mediated transformation
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0010162Biological Processseed dormancy process
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005618Cellular Componentcell wall
GO:0005730Cellular Componentnucleolus
GO:0005739Cellular Componentmitochondrion
GO:0005774Cellular Componentvacuolar membrane
GO:0005829Cellular Componentcytosol
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 287 aa     Download sequence    Send to blast
MEFWGVEVKA GEPLKVVPEE SYVIHLSQAT LGELKKGGDQ CVIHVKVGNQ KLVLANLSSD  60
KMPQIPFDLV FDKEFELSHN LKSGSVHFCG YQTYIANESD EDQXDFDSES EEDLPLNFTG  120
NGNIVEAKPA PPKTNTVKPE SSGKQKVKIE EPIKDEDDSD DSDEDDSDDD ESSDEDMLGA  180
DSSDEDEEDS EEEEDTPTPK KDSKKRPNES APKTPVSAKK AKQVTPQKTD GKKGAHTATP  240
HPAKKGGKTP QTPNSAGGDH SCKTCSKSFN SDGALSSHNK AKHGAKX
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.23510.0bud| cell culture| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during fertilization, while it is repressed during seed development. {ECO:0000269|PubMed:15082924}.
UniprotTISSUE SPECIFICITY: Predominantly expressed in ovaries. Accumulates predominantly in the micropylar region of the ovule's integument. {ECO:0000269|PubMed:15082924}.
Functional Description ? help Back to Top
Source Description
UniProtMediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). {ECO:0000250}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By fertilization. {ECO:0000269|PubMed:15082924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008355217.20.0histone deacetylase HDT1-like
SwissprotQ6V9I67e-67HDT1_SOLCH; Histone deacetylase HDT1
TrEMBLA0A498J4Z70.0A0A498J4Z7_MALDO; Uncharacterized protein
STRINGXP_008355217.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10253067
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G44750.22e-35histone deacetylase 3
Publications ? help Back to Top
  1. Lagacé M,Chantha SC,Major G,Matton DP
    Fertilization induces strong accumulation of a histone deacetylase (HD2) and of other chromatin-remodeling proteins in restricted areas of the ovules.
    Plant Mol. Biol., 2003. 53(6): p. 759-69
    [PMID:15082924]