PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000315466

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 490aa MW: 53481.4 Da PI: 7.3907

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000315466	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15	6.9e-05	133	155	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp+Cg+sF++ + +H ++ MDP0000315466 133 FECPICGQSFRSEDXVSVHVDSC 155 89*************99998766 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.10.20.90	1.4E-9	21	65	No hit	No description
CDD	cd09212	2.19E-21	187	282	No hit	No description
SuperFamily	SSF143503	4.97E-18	197	279	IPR018997	PUB domain
SMART	SM00580	4.2E-19	200	267	IPR018997	PUB domain
Pfam	PF09409	8.2E-16	201	274	IPR018997	PUB domain
SuperFamily	SSF54236	3.1E-12	344	457	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	1.4E-9	361	455	No hit	No description
PROSITE profile	PS50033	11.653	373	457	IPR001012	UBX domain
Pfam	PF00789	4.7E-6	374	424	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 490 aa Download sequence Send to blast
MDDMKDKFKG FMKTTFSSSS SAKFKGQGRV LGSSSSSGTA DSVLTRPKQT PQSNPKPLPN 60 SNSNSSVASP NPRPSPQKAQ ILDQKKTQIP DQSKAEPSGN SKPDRKTDSG FDPFDSLITP 120 GKRSQNGFTL NVFECPICGQ SFRSEDXVSV HVDSCVNAPV EHKSVEGVGV SGSPDNGSDS 180 SRSDLEAXIG TFASGNPAAG SVEVVLRLLR NIVKEPENVK FRKIRMSNPK IREAIGEVVG 240 GIELLEFVGF ELKEEDGEMW ALMGVPKEEQ ISLMKKAIAL LEPPKVQEVD ILPSIASLNV 300 DEPVEPKKVD RQTRVFFSVS ESMAARIEVP ASFYNLTATE LKREAEMRKK KIEDSQMLIP 360 KSFREKQAKA AKRRYRKTVI RIQFPDGVVL QGVFSPLEPT SSLYEYVSSA LKEPSLEFEL 420 LNPVAIKRRV IPHFPAAGEK AATLADEDLM PSALVKFKPI ETDSVVFTGL CNELLEISEP 480 LTSGSAVAPV

Sequence ? help Back to Top

Protein Sequence Length: 490 aa Download sequence Send to blast

MDDMKDKFKG FMKTTFSSSS SAKFKGQGRV LGSSSSSGTA DSVLTRPKQT PQSNPKPLPN  60
SNSNSSVASP NPRPSPQKAQ ILDQKKTQIP DQSKAEPSGN SKPDRKTDSG FDPFDSLITP  120
GKRSQNGFTL NVFECPICGQ SFRSEDXVSV HVDSCVNAPV EHKSVEGVGV SGSPDNGSDS  180
SRSDLEAXIG TFASGNPAAG SVEVVLRLLR NIVKEPENVK FRKIRMSNPK IREAIGEVVG  240
GIELLEFVGF ELKEEDGEMW ALMGVPKEEQ ISLMKKAIAL LEPPKVQEVD ILPSIASLNV  300
DEPVEPKKVD RQTRVFFSVS ESMAARIEVP ASFYNLTATE LKREAEMRKK KIEDSQMLIP  360
KSFREKQAKA AKRRYRKTVI RIQFPDGVVL QGVFSPLEPT SSLYEYVSSA LKEPSLEFEL  420
LNPVAIKRRV IPHFPAAGEK AATLADEDLM PSALVKFKPI ETDSVVFTGL CNELLEISEP  480
LTSGSAVAPV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	2e-13	328	457	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.8146	0.0	bud\| flower\| leaf

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028947119.1	0.0	plant UBX domain-containing protein 2-like
Swissprot	Q9ZU93	1e-179	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A498IDB4	0.0	A0A498IDB4_MALDO; Uncharacterized protein
STRING	XP_009351535.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8944	25	29

Link Out ? help Back to Top
Phytozome	MDP0000315466

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]