PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000301101

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

HSF

Protein Properties

Length: 483aa MW: 53803.5 Da PI: 5.0835

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000301101	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	110.5	1.2e-34	16	106	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelleki 97 Fl k+y++++d++++e++sws+n++sfvv+++ ef++ +Lp+yFkh+nf+SF+RQLn+YgF+k++ e+ weF+++ F +++k+ll++i MDP0000301101 16 FLLKTYNMVDDSATDEIVSWSSNKKSFVVWNPPEFSRVLLPTYFKHNNFSSFIRQLNTYGFRKSDPER---------WEFANEDFIQDQKHLLKNI 102 9************************************************************99988.........*************** PP XXXX CS HSF_DNA-bind 98 krkk 101 +r+k MDP0000301101 103 HRRK 106 98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	3.67E-34	12	105	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.7E-58	12	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	5.3E-37	12	105	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	4.9E-30	16	105	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.1E-18	16	39	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.1E-18	54	66	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.1E-18	67	79	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 483 aa Download sequence Send to blast
MEGGSTAGGG GGPAPFLLKT YNMVDDSATD EIVSWSSNKK SFVVWNPPEF SRVLLPTYFK 60 HNNFSSFIRQ LNTYGFRKSD PERWEFANED FIQDQKHLLK NIHRRKPIHS HSNPQGSMVD 120 PERAALDDEI EKLSHDKDTL EASISTFKQQ QSAAKLQLEN LAQRVSGMEQ RQKNLLTFLD 180 EAVHNPNFIE HLSRKIESMD FSAYNKKRRL PDIENLQPVV ENGFVDNQSS SRSEFGNVFH 240 QDFSSKLRLE LSPAVSDMNL VSLSTQSSNE DGGSSTRKIS EELKGAQMRT EGLLFAPETL 300 ELSDTGTSFA FKMDSLLLLK APTVGSPIRH SLQPGLPSNE EGDGHISCQL NLTLASTPSQ 360 VNNSPYSAAV PQVGQDINKS AASELNDNGK EPDLRAFTKK NLADDDKPKT SFPEATHNNQ 420 APALVSVRVN DVFWEQFLTE RPGCSENEEA SSNYRGNPYD EQDDGRFGHG MSRTVKDAET 480 LTL

Sequence ? help Back to Top

Protein Sequence Length: 483 aa Download sequence Send to blast

MEGGSTAGGG GGPAPFLLKT YNMVDDSATD EIVSWSSNKK SFVVWNPPEF SRVLLPTYFK  60
HNNFSSFIRQ LNTYGFRKSD PERWEFANED FIQDQKHLLK NIHRRKPIHS HSNPQGSMVD  120
PERAALDDEI EKLSHDKDTL EASISTFKQQ QSAAKLQLEN LAQRVSGMEQ RQKNLLTFLD  180
EAVHNPNFIE HLSRKIESMD FSAYNKKRRL PDIENLQPVV ENGFVDNQSS SRSEFGNVFH  240
QDFSSKLRLE LSPAVSDMNL VSLSTQSSNE DGGSSTRKIS EELKGAQMRT EGLLFAPETL  300
ELSDTGTSFA FKMDSLLLLK APTVGSPIRH SLQPGLPSNE EGDGHISCQL NLTLASTPSQ  360
VNNSPYSAAV PQVGQDINKS AASELNDNGK EPDLRAFTKK NLADDDKPKT SFPEATHNNQ  420
APALVSVRVN DVFWEQFLTE RPGCSENEEA SSNYRGNPYD EQDDGRFGHG MSRTVKDAET  480
LTL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	7e-20	9	105	19	129	Heat shock factor protein 1
5d5v_B	7e-20	9	105	19	129	Heat shock factor protein 1
5d5v_D	7e-20	9	105	19	129	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KR132193	0.0	KR132193.1 Eriobotrya japonica heat shock factor 2 (HSF2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008380467.1	0.0	heat stress transcription factor A-5-like
Refseq	XP_008380468.1	0.0	heat stress transcription factor A-5-like
Swissprot	Q94BZ5	1e-158	HSFA5_ARATH; Heat stress transcription factor A-5
TrEMBL	A0A172C4J7	0.0	A0A172C4J7_9ROSA; Heat shock factor 2
STRING	XP_008380467.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4961	32	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G13980.1	1e-161	HSF family protein

Link Out ? help Back to Top
Phytozome	MDP0000301101

Publications ? help Back to Top
Reňák D,Gibalová A,Solcová K,Honys D A new link between stress response and nucleolar function during pollen development in Arabidopsis mediated by AtREN1 protein. Plant Cell Environ., 2014. 37(3): p. 670-83 [PMID:23961845]