PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000300712
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family WRKY
Protein Properties Length: 738aa    MW: 80464.2 Da    PI: 7.1432
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000300712genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY96.22.2e-30311370159
                    ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
           WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                    ++Dg++WrKYGqK  kg+++pr+YYrCt a +Cpv+k+v+r+aed +++++tYeg+Hnh+
  MDP0000300712 311 MNDGCQWRKYGQKIAKGNPCPRAYYRCTIApSCPVRKQVQRCAEDMSILITTYEGNHNHP 370
                    58***************************99****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.1E-31296372IPR003657WRKY domain
SuperFamilySSF1182903.4E-27303372IPR003657WRKY domain
PROSITE profilePS5081128.461306372IPR003657WRKY domain
SMARTSM007741.7E-36311371IPR003657WRKY domain
PfamPF031061.7E-26312370IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 738 aa     Download sequence    Send to blast
MEAALGKSNS HGGSEREEKT VVLESSSIAD DQEAGSREEI VLKVGNGRPC QENNEVKSSS  60
PKQKEFELQA EVLKLGYVHH QSTSTICFRY LTKIVKYWNR AGSSAEPDHS AASTSPSIKE  120
KDCQLESARA EMGEVREENQ RLKKYLDRIT EEYQTLQMQL YDIQQKANKS KDIAIPSTNK  180
NYDQDEESEL VSLSLGSFSG KPKWNQKNDK NPSTSQGKVE NESDGESLSL GLDCKYEAPK  240
SSATTDQVPL ANPSPRSSLE EVPKEEAGET WPPRKVLKTV RSSGMEDEVV QQSPAKKARV  300
SVRVRCDTPT MNDGCQWRKY GQKIAKGNPC PRAYYRCTIA PSCPVRKQVQ RCAEDMSILI  360
TTYEGNHNHP LPMSATAMAS TTSAAASMLL SGSSSSSSGH LNPSATATST TAAHDLHGYN  420
FYLSDNSKSR FYTPNSSLSS SLPTVILDLT SKPSSTSNSM SHFNKFSSSS SSSHQLYPPT  480
SLNFGSNSES STNMSWSNNG LLPYGTHLPP YNISNKNQSA PLSSLGIRQQ HMQNNIYQNY  540
MQKNINPHPN PPQGVPHQFQ PDSIAAATKA ITSDPSFQSA LAAALTSIIG SNSTVGTTGI  600
AGTLGHINQA GGGDSSISLA QKFKWNDHFP GSTTTTTSSS SPFLQSQIGF CSWVSALDLK  660
GDTDGWKSWA FVVQIVVTMT SLVLLMLYNA AANTVLYMYC RAMNGELTME IAKEFAREYX  720
SLPFDNEKVP HVVSVAHA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-213113721777Probable WRKY transcription factor 4
2lex_A2e-213113721777Probable WRKY transcription factor 4
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269|PubMed:24884371}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269|PubMed:20409007, ECO:0000269|PubMed:24884371}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269|PubMed:20409007}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008374532.20.0LOW QUALITY PROTEIN: probable WRKY transcription factor 61
SwissprotA0A3Q7GFB51e-118WK72A_SOLLC; WRKY transcription factor 72A
TrEMBLA0A498JMN90.0A0A498JMN9_MALDO; Uncharacterized protein
STRINGXP_008374532.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF65034134
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G15130.11e-59WRKY DNA-binding protein 72
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]