PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000295064

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 1177aa MW: 130278 Da PI: 8.0378

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000295064	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.9	0.00033	1016	1035	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ MDP0000295064 1016 FSCPLCFKTFNRYNNMQMHM 1035 89*****************9 PP
2	zf-C2H2	12.4	0.0005	1100	1122	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk F + + ++H +++ MDP0000295064 1100 FMCRKCGKAFAVRGDWRTHEKNC 1122 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.40.160.50	3.4E-25	351	560	No hit	No description
Pfam	PF01103	1.1E-41	393	745	IPR000184	Bacterial surface antigen (D15)
Gene3D	G3DSA:2.40.160.50	3.4E-25	598	733	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.2E-4	1016	1035	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	9.66	1016	1043	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.61	1016	1038	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1018	1038	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	7.14E-6	1082	1120	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.1E-5	1096	1120	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	8.808	1100	1120	IPR007087	Zinc finger, C2H2
SMART	SM00355	49	1100	1120	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009658	Biological Process	chloroplast organization
GO:0005739	Cellular Component	mitochondrion
GO:0009941	Cellular Component	chloroplast envelope
GO:0019867	Cellular Component	outer membrane
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1177 aa Download sequence Send to blast
MPPNDDVRFT SSPSAKVPRS PENRHVDLTV LFARTRNSFS QLIDSLRIRS SFPKFPPLPI 60 LCSASLSLTR HADSAESEWR NRNADRGRFV GKSPLLCSAS LALTRPDEST QSQQKGHASS 120 RHDEERVLIS EVLVRNKDGE ELERKDLEME ALAALKACRA NSALTVREVQ EDVHRIIDSG 180 YFCSCMPVAV DTRDGIRLIF QVKPNQEFQG LVCEGANVLP AKFLKDAFCD GYGKVINLKR 240 LNEVISSIND WYMDRGLFAM VSAVEILSGG ILKLQVSETE VNNISMRFLD RKTGEPTIGK 300 TKPXTILRQL TTKKGQVYSM LQGKRDVETV LTMGLMEDVS IIPQPADAGK VDITMNVVER 360 PSGGFSAGGG ISSGITSGPL SGLIGSFAYS HRNLFGRNQK LHVSLERGQI DSIFRINYSD 420 PWIAGDDKRT SRTIMVQNST TPGTLIHGNQ LNGSNLTIGR VTAGIEFSRP IRPKFSGTAG 480 LIFQHAGARD EKGDPIIKDV YSSPLTASGN THDDMLLAKL ESVYTGSGDH GSSMCVFNVE 540 QGLPVLPEWL YFNRINARAR KDVELGPTRV LVRYDHSVFV TVGAIYQKTY PSPNTPPPRY 600 CNCXFEVKLV IXSFGXDFVX LCPASLSGGH VVGNFPPHEA FGIGGTNSVR GYEEGAVGSG 660 RSYAVGSGEI SFPMIGPVGG VIFADYGTDL GSGPTVPGDP AGARHKPGSG YGYGFGIRLD 720 SPLGPLRLEY AFNDQHAKRF HFGVAHAAFL HAVFQYSSYY FRVLRYTLPH QTTXNFHCLK 780 NTNHPYCPLG QVRLQLLAGG RYQPIYSTDV ANTDANDSRF RAHPYPNYFN NGWFNINXVH 840 HFSSTSTPSS XNPYNYHPPN YGDYHNFCSS NNLINNINNT LFTNHHHQSS SPPSPPLREA 900 LPLLSQSPSR NHHHEDMQES AAADDHQSFL SSSRSDDIVD HQEEDDETVT VALHLGLPSR 960 TLSSADLISR LSSPEIPSDK EADVTVASAG FASNRLNKGQ YWIPTPAQIL IGPTQFSCPL 1020 CFKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTAMLRL PCYCCAPGCR NNIDHPRAKP 1080 LKDFRTLQTH YKRKHGIKPF MCRKCGKAFA VRGDWRTHEK NCGKLWYCTC GSDFKHKRSL 1140 KDHIKAFGQG HAAYGIDCFE EEDDVASEIE ENDSSSH

Sequence ? help Back to Top

Protein Sequence Length: 1177 aa Download sequence Send to blast

MPPNDDVRFT SSPSAKVPRS PENRHVDLTV LFARTRNSFS QLIDSLRIRS SFPKFPPLPI  60
LCSASLSLTR HADSAESEWR NRNADRGRFV GKSPLLCSAS LALTRPDEST QSQQKGHASS  120
RHDEERVLIS EVLVRNKDGE ELERKDLEME ALAALKACRA NSALTVREVQ EDVHRIIDSG  180
YFCSCMPVAV DTRDGIRLIF QVKPNQEFQG LVCEGANVLP AKFLKDAFCD GYGKVINLKR  240
LNEVISSIND WYMDRGLFAM VSAVEILSGG ILKLQVSETE VNNISMRFLD RKTGEPTIGK  300
TKPXTILRQL TTKKGQVYSM LQGKRDVETV LTMGLMEDVS IIPQPADAGK VDITMNVVER  360
PSGGFSAGGG ISSGITSGPL SGLIGSFAYS HRNLFGRNQK LHVSLERGQI DSIFRINYSD  420
PWIAGDDKRT SRTIMVQNST TPGTLIHGNQ LNGSNLTIGR VTAGIEFSRP IRPKFSGTAG  480
LIFQHAGARD EKGDPIIKDV YSSPLTASGN THDDMLLAKL ESVYTGSGDH GSSMCVFNVE  540
QGLPVLPEWL YFNRINARAR KDVELGPTRV LVRYDHSVFV TVGAIYQKTY PSPNTPPPRY  600
CNCXFEVKLV IXSFGXDFVX LCPASLSGGH VVGNFPPHEA FGIGGTNSVR GYEEGAVGSG  660
RSYAVGSGEI SFPMIGPVGG VIFADYGTDL GSGPTVPGDP AGARHKPGSG YGYGFGIRLD  720
SPLGPLRLEY AFNDQHAKRF HFGVAHAAFL HAVFQYSSYY FRVLRYTLPH QTTXNFHCLK  780
NTNHPYCPLG QVRLQLLAGG RYQPIYSTDV ANTDANDSRF RAHPYPNYFN NGWFNINXVH  840
HFSSTSTPSS XNPYNYHPPN YGDYHNFCSS NNLINNINNT LFTNHHHQSS SPPSPPLREA  900
LPLLSQSPSR NHHHEDMQES AAADDHQSFL SSSRSDDIVD HQEEDDETVT VALHLGLPSR  960
TLSSADLISR LSSPEIPSDK EADVTVASAG FASNRLNKGQ YWIPTPAQIL IGPTQFSCPL  1020
CFKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTAMLRL PCYCCAPGCR NNIDHPRAKP  1080
LKDFRTLQTH YKRKHGIKPF MCRKCGKAFA VRGDWRTHEK NCGKLWYCTC GSDFKHKRSL  1140
KDHIKAFGQG HAAYGIDCFE EEDDVASEIE ENDSSSH

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2x8x_X	2e-27	123	360	1	233	TLR1789 PROTEIN
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.23257	0.0	bud\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed throughout development. {ECO:0000269\|PubMed:18621981}.

Functional Description ? help Back to Top
Source	Description
UniProt	Plays an essential role during early stages of plastid development. {ECO:0000269\|PubMed:18621981}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028955214.1	0.0	outer envelope protein 80, chloroplastic-like isoform X1
Swissprot	Q9C5J8	0.0	OEP80_ARATH; Outer envelope protein 80, chloroplastic
TrEMBL	A0A498K9D8	0.0	A0A498K9D8_MALDO; Uncharacterized protein
STRING	XP_009374482.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF9743	2	2

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-117	C2H2 family protein

Link Out ? help Back to Top
Phytozome	MDP0000295064

Publications ? help Back to Top
Gutensohn M,Schulz B,Nicolay P,Flügge UI Functional analysis of the two Arabidopsis homologues of Toc34, a component of the chloroplast protein import apparatus. Plant J., 2000. 23(6): p. 771-83 [PMID:10998188] Eckart K, et al. A Toc75-like protein import channel is abundant in chloroplasts. EMBO Rep., 2002. 3(6): p. 557-62 [PMID:12034753] Inoue K,Potter D The chloroplastic protein translocation channel Toc75 and its paralog OEP80 represent two distinct protein families and are targeted to the chloroplastic outer envelope by different mechanisms. Plant J., 2004. 39(3): p. 354-65 [PMID:15255865] Miras S, et al. Toc159- and Toc75-independent import of a transit sequence-less precursor into the inner envelope of chloroplasts. J. Biol. Chem., 2007. 282(40): p. 29482-92 [PMID:17636260] Kalanon M,McFadden GI The chloroplast protein translocation complexes of Chlamydomonas reinhardtii: a bioinformatic comparison of Toc and Tic components in plants, green algae and red algae. Genetics, 2008. 179(1): p. 95-112 [PMID:18493043] Patel R,Hsu SC,Bédard J,Inoue K,Jarvis P The Omp85-related chloroplast outer envelope protein OEP80 is essential for viability in Arabidopsis. Plant Physiol., 2008. 148(1): p. 235-45 [PMID:18621981] Jarvis P Targeting of nucleus-encoded proteins to chloroplasts in plants. New Phytol., 2008. 179(2): p. 257-85 [PMID:19086173] Agne B, et al. A toc159 import receptor mutant, defective in hydrolysis of GTP, supports preprotein import into chloroplasts. J. Biol. Chem., 2009. 284(13): p. 8670-9 [PMID:19188370] Shipman RL,Inoue K Suborganellar localization of plastidic type I signal peptidase 1 depends on chloroplast development. FEBS Lett., 2009. 583(5): p. 938-42 [PMID:19223000] Sun CW,Huang YC,Chang HY CIA2 coordinately up-regulates protein import and synthesis in leaf chloroplasts. Plant Physiol., 2009. 150(2): p. 879-88 [PMID:19386807] Jouhet J,Gray JC Interaction of actin and the chloroplast protein import apparatus. J. Biol. Chem., 2009. 284(28): p. 19132-41 [PMID:19435889] Hsu SC,Patel R,Bédard J,Jarvis P,Inoue K Two distinct Omp85 paralogs in the chloroplast outer envelope membrane are essential for embryogenesis in Arabidopsis thaliana. Plant Signal Behav, 2008. 3(12): p. 1134-5 [PMID:19704458] Meinke D,Sweeney C,Muralla R Integrating the genetic and physical maps of Arabidopsis thaliana: identification of mapped alleles of cloned essential (EMB) genes. PLoS ONE, 2009. 4(10): p. e7386 [PMID:19812694] Shipman-Roston RL,Ruppel NJ,Damoc C,Phinney BS,Inoue K The significance of protein maturation by plastidic type I signal peptidase 1 for thylakoid development in Arabidopsis chloroplasts. Plant Physiol., 2010. 152(3): p. 1297-308 [PMID:20097790] Bryant N,Lloyd J,Sweeney C,Myouga F,Meinke D Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis. Plant Physiol., 2011. 155(4): p. 1678-89 [PMID:21139083] Huang W,Ling Q,Bédard J,Lilley K,Jarvis P In vivo analyses of the roles of essential Omp85-related proteins in the chloroplast outer envelope membrane. Plant Physiol., 2011. 157(1): p. 147-59 [PMID:21757633] Sommer MS, et al. Chloroplast Omp85 proteins change orientation during evolution. Proc. Natl. Acad. Sci. U.S.A., 2011. 108(33): p. 13841-6 [PMID:21825140] Hsu SC,Nafati M,Inoue K OEP80, an essential protein paralogous to the chloroplast protein translocation channel Toc75, exists as a 70-kD protein in the Arabidopsis thaliana chloroplast outer envelope. Plant Mol. Biol., 2012. 78(1-2): p. 147-58 [PMID:22094888] Töpel M,Ling Q,Jarvis P Neofunctionalization within the Omp85 protein superfamily during chloroplast evolution. Plant Signal Behav, 2012. 7(2): p. 161-4 [PMID:22307047] Day PM,Potter D,Inoue K Evolution and targeting of Omp85 homologs in the chloroplast outer envelope membrane. Front Plant Sci, 2014. 5: p. 535 [PMID:25352854] Paila YD, et al. Multi-functional roles for the polypeptide transport associated domains of Toc75 in chloroplast protein import. Elife, 2017. [PMID:26999824] Patton DA, et al. An embryo-defective mutant of arabidopsis disrupted in the final step of biotin synthesis Plant Physiol., 1998. 116(3): p. 935-46 [PMID:9501126]