PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000256090

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 259aa MW: 29573.8 Da PI: 10.4207

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000256090	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.5	2.3e-05	121	143	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H + H MDP0000256090 121 FVCEICNKGFQRDQNLQLHRQGH 143 89*****************9877 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF12171	2.0E-5	120	143	IPR022755	Zinc finger, double-stranded RNA binding
SuperFamily	SSF57667	1.27E-6	120	143	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.2E-4	120	143	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.346	121	143	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.028	121	143	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	123	143	IPR007087	Zinc finger, C2H2
SMART	SM00355	72	162	192	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	1.27E-6	192	218	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 259 aa Download sequence Send to blast
MEERESSVGR RRLAQRRKWR TPKSPFLPFA KVAISALTFP LKNPQRFAVN NLGSLGPSDV 60 EEGSFSSGNN TGELEVRQDQ KQQENHLHRS SSGGAFGAQS NNPSAEVIAL SPTTLMATNQ 120 FVCEICNKGF QRDQNLQLHR QGHNLPWKLW QRTTTEVRKR VYICPEPTCV HHNPTWVLGD 180 LTGIKKHFSR KHGEKKWKWD KCSKKYAVQS DWKAHQKTCG TRDINVTVEP SFLRNFIWCL 240 MQLLQLLLLI PPGDHPGVL

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in the ground tissue and stele cells of embryos and 2-days post-germination roots but not in the quiescent center (PubMed:17785527). Detected only in cells that perform asymmetric cell divisions (PubMed:17785527). In roots, present in cortex, endodermis, and pericycle layer (PubMed:25829440). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:25829440}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006480107.1	3e-85	protein indeterminate-domain 2-like
Swissprot	Q9ZWA6	7e-69	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	A0A498K8F8	1e-101	A0A498K8F8_MALDO; Uncharacterized protein
STRING	XP_008386763.1	1e-104	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.2	1e-63	C2H2 family protein

Link Out ? help Back to Top
Phytozome	MDP0000256090

Publications ? help Back to Top
Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]