PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000249592
Common NameMADS21
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MIKC_MADS
Protein Properties Length: 224aa    MW: 25801.6 Da    PI: 9.4655
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000249592genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF85.33.6e-27959151
                   S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
         SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                   krien + rqvt skRrng+lKKA+E SvLCdaevaviifs++++lye+ss
  MDP0000249592  9 KRIENATSRQVTXSKRRNGLLKKAYEXSVLCDAEVAVIIFSQKDRLYEFSS 59
                   79***********************************************96 PP
2K-box60.28.3e-2177157483
          K-box   4 ssgks.leeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkk 83 
                     ++++   e++ ++l++e+a + k+ie L+ +qR+llG+dL+s+ ++eLq+L +qLe+sl++iR++K+ lll++  +l+++
  MDP0000249592  77 EQTNKvEVEQHVQHLKHESAIMAKKIEILEATQRKLLGNDLDSCYVEELQELSSQLERSLRSIRERKETLLLQENAKLREQ 157
                    34444478999**************************************************************99999875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006629.997161IPR002100Transcription factor, MADS-box
SMARTSM004321.0E-35160IPR002100Transcription factor, MADS-box
PRINTSPR004041.2E-27323IPR002100Transcription factor, MADS-box
CDDcd002654.19E-38378No hitNo description
SuperFamilySSF554554.06E-30389IPR002100Transcription factor, MADS-box
PfamPF003196.0E-231057IPR002100Transcription factor, MADS-box
PRINTSPR004041.2E-272338IPR002100Transcription factor, MADS-box
PRINTSPR004041.2E-273859IPR002100Transcription factor, MADS-box
PfamPF014864.5E-1885158IPR002487Transcription factor, K-box
PROSITE profilePS5129712.00888184IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 224 aa     Download sequence    Send to blast
MVRGKIXMKR IENATSRQVT XSKRRNGLLK KAYEXSVLCD AEVAVIIFSQ KDRLYEFSSS  60
DMRETLTRYR KYAKDHEQTN KVEVEQHVQH LKHESAIMAK KIEILEATQR KLLGNDLDSC  120
YVEELQELSS QLERSLRSIR ERKETLLLQE NAKLREQSGA KLWMEHSVQA KRASTLSYEK  180
AGVSASVNYR SQGSMSSEVE TELFIGPPIM RAVDASQPES TYIR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6bz1_A1e-21185186MEF2 CHIMERA
6bz1_B1e-21185186MEF2 CHIMERA
6bz1_C1e-21185186MEF2 CHIMERA
6bz1_D1e-21185186MEF2 CHIMERA
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the shoot apical meristem (SAM) during the vegetative phase and the floral transition. After floral transition, expressed in apical meristem (AM), inflorescence meristem (IM) and floral primordia. {ECO:0000269|PubMed:21609362}.
UniprotTISSUE SPECIFICITY: Expressed in quiescent center (QC) cells of root tips (PubMed:18162590, PubMed:21689171). Expressed at the base of the petiole of cotyledons and leaves, in flower buds, petals, sepals and abscission zone of flowers and siliques. {ECO:0000269|PubMed:18162590, ECO:0000269|PubMed:21689171}.
Functional Description ? help Back to Top
Source Description
UniProtMADS-box transcription factor that acts with AGL71 and AGL72 in the control of flowering time. Promotes flowering at the shoot apical and axillary meristems. Seems to act through a gibberellin-dependent pathway. Interacts genetically with SOC1 and its expression is directly regulated by SOC1 (PubMed:21609362). Plays a role in controlling flower organ senescence and abscission by repressing ethylene responses and regulating the expression of BOP2 and IDA (PubMed:21689171). {ECO:0000269|PubMed:21609362, ECO:0000269|PubMed:21689171}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP1640111e-180KP164011.1 Pyrus pyrifolia clone PpSOC1-2 SOC1-like MADS-box protein mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280901.11e-157MADS-box protein SOC1-like
RefseqXP_017190278.21e-157MADS-box protein SOC1-like isoform X1
SwissprotQ9FIS11e-65AGL42_ARATH; MADS-box protein AGL42
TrEMBLD9ZJ411e-156D9ZJ41_MALDO; MADS domain class transcription factor
STRINGXP_008376883.11e-157(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66630102
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62165.43e-58AGAMOUS-like 42