PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000247896

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

WRKY

Protein Properties

Length: 316aa MW: 35938.2 Da PI: 4.9401

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000247896	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	93.9	1.2e-29	130	187	2	58
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnh 58 +D ++WrKYGqK++kgs++prsYYrC+s+ gC+++k+vers ++p++++itY+ eHnh MDP0000247896 130 SDVWAWRKYGQKPIKGSPYPRSYYRCSSSkGCSARKQVERSCSNPETFIITYTAEHNH 187 79***********************998************************** PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.0E-30	115	189	IPR003657	WRKY domain
PROSITE profile	PS50811	33.109	124	190	IPR003657	WRKY domain
SuperFamily	SSF118290	3.53E-25	126	190	IPR003657	WRKY domain
SMART	SM00774	5.4E-32	129	189	IPR003657	WRKY domain
Pfam	PF03106	4.9E-25	131	187	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010200	Biological Process	response to chitin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 316 aa Download sequence Send to blast
MENWDLQAVV RGCNNNIDEV MEDSQIPYFC APLSFQEDNE LFAAKFPQAF EATTTLDELE 60 ELYKPFYPVF QLTTPPTILT SSISVPQEII TLAPKLIKNM EESTPVRKRI SRKNQNKRVV 120 KEVKAEDLFS DVWAWRKYGQ KPIKGSPYPR SYYRCSSSKG CSARKQVERS CSNPETFIIT 180 YTAEHNHVYP TRRNSLAGST RSKFSSSKNK DKCGSSLNSP ATPNIAASIE DDREFVESVN 240 INAVKVEAKL SEQDEISKEN FFLDTTVNDE IFPSLEDLDR KLEPVMDGWF SDEFSDNFPS 300 PWFNIKGHSN TVTGAC

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-19	120	190	8	77	Probable WRKY transcription factor 4
2lex_A	1e-19	120	190	8	77	Probable WRKY transcription factor 4
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.30231	1e-129	leaf

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates WRKY 22, SIRK and its own promoters. {ECO:0000269\|PubMed:11875555}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00448	DAP	Transfer from AT4G23550	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced 30 minutes after flagellin treatment. {ECO:0000269\|PubMed:11875555}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GU013683	4e-98	GU013683.1 Malus x domestica transcription factor WRKY (WRKY) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008375964.1	0.0	probable WRKY transcription factor 29 isoform X1
Swissprot	Q9SUS1	9e-61	WRK29_ARATH; Probable WRKY transcription factor 29
TrEMBL	A0A498JKS6	0.0	A0A498JKS6_MALDO; Uncharacterized protein
STRING	XP_008375964.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6217	31	50

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G23550.1	1e-38	WRKY family protein

Link Out ? help Back to Top
Phytozome	MDP0000247896

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Liu XQ, et al. OsWRKY03, a rice transcriptional activator that functions in defense signaling pathway upstream of OsNPR1. Cell Res., 2005. 15(8): p. 593-603 [PMID:16117849] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Yi SY,Shirasu K,Moon JS,Lee SG,Kwon SY The activated SA and JA signaling pathways have an influence on flg22-triggered oxidative burst and callose deposition. PLoS ONE, 2014. 9(2): p. e88951 [PMID:24586453] Cambiagno DA,Lonez C,Ruysschaert JM,Alvarez ME The synthetic cationic lipid diC14 activates a sector of the Arabidopsis defence network requiring endogenous signalling components. Mol. Plant Pathol., 2015. 16(9): p. 963-72 [PMID:25727690] Gkizi D, et al. The Innate Immune Signaling System as a Regulator of Disease Resistance and Induced Systemic Resistance Activity Against Verticillium dahliae. Mol. Plant Microbe Interact., 2016. 29(4): p. 313-23 [PMID:26780421] Li Y,Williams B,Dickman M Arabidopsis B-cell lymphoma2 (Bcl-2)-associated athanogene 7 (BAG7)-mediated heat tolerance requires translocation, sumoylation and binding to WRKY29. New Phytol., 2017. 214(2): p. 695-705 [PMID:28032645] Wang S, et al. Bacillus cereus AR156 Activates Defense Responses to Pseudomonas syringae pv. tomato in Arabidopsis thaliana Similarly to flg22. Mol. Plant Microbe Interact., 2018. 31(3): p. 311-322 [PMID:29090631]