PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000242185
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family TCP
Protein Properties Length: 399aa    MW: 42547.1 Da    PI: 7.2646
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000242185genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP128.56.8e-4062173289
            TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg........ 88 
                    ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+p+++++tgt++++a+++  + s +ss+s+ s++        
  MDP0000242185  62 PPKRTSTKDRHTKVDGRGRRIRMPATCAARVFQLTRELGHKSDGETIEWLLQQAEPSVIAATGTGTIPANFTsLNISLRSSGSSMSAPshylrtna 157
                    789******************************************************************999866777777664444444455444 PP

            TCP  89 ...............k 89 
                                    
  MDP0000242185 158 snyyfnsnnfgaaapT 173
                    4444444444433330 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036344.1E-4166252IPR005333Transcription factor, TCP
PROSITE profilePS5136927.21868122IPR017887Transcription factor TCP subgroup
Sequence ? help Back to Top
Protein Sequence    Length: 399 aa     Download sequence    Send to blast
MEADNGIRCR PNFPLQFLDK TNQVDDDPEP AAACSTVADP GSDPNRTGSS IQEEQPSNKK  60
PPPKRTSTKD RHTKVDGRGR RIRMPATCAA RVFQLTRELG HKSDGETIEW LLQQAEPSVI  120
AATGTGTIPA NFTSLNISLR SSGSSMSAPS HYLRTNASNY YFNSNNFGAA APTAQLGTAE  180
HSQRGRILFP GAGLMSSESS PPSSMLWNFN NSGNNNLSNN TMLEAKQELG DHHQAVTLDE  240
ASSMARKRIR PEQDLLSAST GSIPASQNTI PATFWMVANN NPSSSQGSIH HEHINSINPM  300
WTIPTVGNAG NMYRGPVAGG GHGLHFMNFA SPLAILPGQQ LGTGSITTTQ GAADGHLGML  360
AALNAYRPIL GGVAMESPVN GQHPHQGADE GHDRNTNAR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.113320.0bud| flower| fruit
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the vascular tissues of the embryo (PubMed:17953649). Expressed in young proliferating tissues (PubMed:21668538). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Involved in the regulation of seed germination. May regulate the activation of embryonic growth potential during seed germination (PubMed:17953649, PubMed:22155632). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). Involved in positive regulation of plant defense. Represses jasmonate (JA) response to promote disease resistance. Regulates the plant immune system by transcriptionally repressing a subset of JA-responsive genes (PubMed:28132837). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22155632, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:28132837}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during seed imbibition (PubMed:17953649). Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:17953649). {ECO:0000269|PubMed:17953649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008389481.30.0transcription factor TCP15-like
SwissprotQ93Z009e-56TCP14_ARATH; Transcription factor TCP14
TrEMBLA0A498I8V00.0A0A498I8V0_MALDO; Uncharacterized protein
STRINGXP_008389481.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF21203280
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G69690.15e-51TCP family protein
Publications ? help Back to Top
  1. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  2. Yang L, et al.
    Pseudomonas syringae Type III Effector HopBB1 Promotes Host Transcriptional Repressor Degradation to Regulate Phytohormone Responses and Virulence.
    Cell Host Microbe, 2017. 21(2): p. 156-168
    [PMID:28132837]
  3. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  4. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]