PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000240840
Common NameAP2D8
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family ERF
Protein Properties Length: 332aa    MW: 37303.7 Da    PI: 7.6625
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000240840genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP265.11.4e-20191242256
            AP2   2 gykGVrwdkkrgrWvAeIrdpseng.krkrfslgkfgtaeeAakaaiaarkklege 56 
                    +y+GVr+++ +g+++AeIrdp   + +  r++lg+f+ta eAa+a+++a+ kl+g+
  MDP0000240840 191 HYRGVRQRP-WGKYAAEIRDP---NrRGSRVWLGTFDTAIEAARAYDRAAFKLRGA 242
                    8********.**********9...4334**************************95 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.107.6E-33190250IPR001471AP2/ERF domain
CDDcd000185.70E-32190249No hitNo description
SMARTSM003802.3E-36191255IPR001471AP2/ERF domain
PfamPF008471.7E-14191241IPR001471AP2/ERF domain
PROSITE profilePS5103224.434191249IPR001471AP2/ERF domain
SuperFamilySSF541712.94E-23191250IPR016177DNA-binding domain
PRINTSPR003671.1E-10192203IPR001471AP2/ERF domain
PRINTSPR003671.1E-10215231IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 332 aa     Download sequence    Send to blast
MALDQVSALX LIKHHLLGEX SPVKSXAIEL SDSASSFPQN QWSPEVNSDL SRSQSDSFCS  60
KSSSTFESSI EISDYLDSTD IFDFNSADFF DFEPKXQVID LTTPKSTSLR SQSSFEFDSK  120
PQVSDDFFGF EQKPQILNQT APKPANPTRK PALTISLPNK TEWIQFASSD QAAXKPAAVQ  180
KVSSNEEKKK HYRGVRQRPW GKYAAEIRDP NRRGSRVWLG TFDTAIEAAR AYDRAAFKLR  240
GAKAILNFPL EAGKAEPVVS VERKRRREER RDEAKEVVVV KKEKLTETPL TPSSWMSFWE  300
SEKEDVKGVF SIPPLSPLSP HPAMGYPQVM VV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A3e-29188256270ATERF1
3gcc_A3e-29188256270ATERF1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1262266RKRRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.53800.0fruit| leaf| stem
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2). Wounding as well as cold stress induction does not require EIN2. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by jasmonate, Alternaria brassicicola, exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269|PubMed:10715325}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGU7324320.0GU732432.1 Malus x domestica AP2 domain class transcription factor (AP2D8) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001315812.10.0ethylene-responsive transcription factor 5-like
SwissprotO803411e-71EF102_ARATH; Ethylene-responsive transcription factor 5
TrEMBLD5L0Z20.0D5L0Z2_MALDO; AP2 domain class transcription factor
STRINGXP_008355567.10.0(Malus domestica)
STRINGXP_008369419.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF108534109
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G47230.15e-49ethylene responsive element binding factor 5
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Tacken E, et al.
    The role of ethylene and cold temperature in the regulation of the apple POLYGALACTURONASE1 gene and fruit softening.
    Plant Physiol., 2010. 153(1): p. 294-305
    [PMID:20237022]