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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
MDP0000232265 |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
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| Family |
E2F/DP |
| Protein Properties |
Length: 385aa MW: 42718.6 Da PI: 4.7494 |
| Description |
E2F/DP family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| MDP0000232265 | genome | GDR | View CDS |
|
| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | E2F_TDP | 85.5 | 4e-27 | 40 | 105 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
r+++sL+llt+kf+ l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
MDP0000232265 40 RYDSSLGLLTKKFIXLIKRAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 105
6899******************************...99..****************************98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0005667 | Cellular Component | transcription factor complex |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 385 aa
Download sequence Send
to blast |
MSTKGGRVNN RSKASKGGRS GPQTPVSNVG SPSTPAGSCR YDSSLGLLTK KFIXLIKRAE 60
DGILDLNKAA ETLEVQKRRI YDITNVLEGI GLIEKKLKNR IRWKGFDASM PGELDGDLSI 120
LQAEVENLSL QERRLDDRIR EMQEKLRDLS EDENNRKWLF VTEDDIKGLP CFHNETLIAI 180
KAPHGTTLEV PDPDEAVDYL QRRYRIILXS TMGPIDVYLV SQFDEKFEDV HGAEPPVSCP 240
MASGSGSSEH PITEVVTVES SGKEIEPWLQ QAHHTCSDLN ASQEFAGGMM KIVPSDVDVQ 300
HKMCIFICLY DDIGKAVQNI NDADYWLLSD AEVSITDMWR TDSGVGWNGT DILHADFGVT 360
DVSTPRPQTP PSRVVEVPSH AVNFA
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
| Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
