PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000210785
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family TCP
Protein Properties Length: 398aa    MW: 42180.8 Da    PI: 10.2213
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000210785genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP132.93e-4168185289
            TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg........ 88 
                    ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++  + s +ss+s+ s +        
  MDP0000210785  68 PPKRTSTKDRHTKVDGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSSGSSMSVPsqlrssyy 163
                    789******************************************************************999877777777775555555555565 PP

            TCP  89 .....................k 89 
                                         +
  MDP0000210785 164 spnfslqqnqrrslfqgiglsS 185
                    5555565555433444444432 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036347.1E-4172210IPR005333Transcription factor, TCP
PROSITE profilePS5136927.92374128IPR017887Transcription factor TCP subgroup
Sequence ? help Back to Top
Protein Sequence    Length: 398 aa     Download sequence    Send to blast
MRSWKEVMII NSTTTTTTIN NTNNINNNIT TPSPPSTPPP PTTRPLLPQP QPPQLSKLLP  60
PSPPKKPPPK RTSTKDRHTK VDGRGRRIRM PALCAARVFQ LTRELGHKSD GETIEWLLQQ  120
AEPAVIAATG TGTIPANFTS LNISLRSSGS SMSVPSQLRS SYYSPNFSLQ QNQRRSLFQG  180
IGLSSSDSSS TLLNFQTNTM HASMLQAKQE LRDTVSLDLS EAASAGEGSL GGRKRRPPEQ  240
DLNHMGGGGG GGGGGGGYLL QSSTGVVPAS HPHSQIPANF WMLANSNNQV MSGDPIWTFP  300
ASVNNSGLYR GTMPGGLHFM NFPAPVTVLP NQQQLSGSGG GGGNDGDNMS DGQLNMLAGL  360
NPYRHMSGTG VSDSQQASGS HSHHGGGDDR HDSTSHHS
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.232890.0bud
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the vascular tissues of the embryo (PubMed:17953649). Expressed in young proliferating tissues (PubMed:21668538). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Involved in the regulation of seed germination. May regulate the activation of embryonic growth potential during seed germination (PubMed:17953649, PubMed:22155632). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). Involved in positive regulation of plant defense. Represses jasmonate (JA) response to promote disease resistance. Regulates the plant immune system by transcriptionally repressing a subset of JA-responsive genes (PubMed:28132837). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22155632, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:28132837}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during seed imbibition (PubMed:17953649). Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:17953649). {ECO:0000269|PubMed:17953649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021820713.10.0transcription factor TCP15-like
SwissprotQ93Z001e-59TCP14_ARATH; Transcription factor TCP14
TrEMBLM5WM860.0M5WM86_PRUPE; Uncharacterized protein
STRINGXP_008393155.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF21203280
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G47620.17e-43TEOSINTE BRANCHED, cycloidea and PCF (TCP) 14
Publications ? help Back to Top
  1. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  2. Yang L, et al.
    Pseudomonas syringae Type III Effector HopBB1 Promotes Host Transcriptional Repressor Degradation to Regulate Phytohormone Responses and Virulence.
    Cell Host Microbe, 2017. 21(2): p. 156-168
    [PMID:28132837]
  3. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  4. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]