PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000209399
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family TALE
Protein Properties Length: 619aa    MW: 68879.7 Da    PI: 7.0312
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000209399genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.82.1e-094134501954
                    HHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS
       Homeobox  19 Fek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 
                    Fe   ++yp+ +++  LAk++gL+ +qV++WF N R +
  MDP0000209399 413 FEHflHPYPTDSDKLMLAKQTGLSRSQVSNWFINARVR 450
                    554459******************************88 PP
2BELL102.14e-33283350572
           BELL   5 lqkkkakLlslleeVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72 
                      +kk++L+s+l+eV++rYkqy++q+q+v+ sFe vaglg+a+pY++lA ka++ hF+cLk+ai++q+
  MDP0000209399 283 STRKKSRLISMLDEVYRRYKQYCQQMQAVARSFEYVAGLGNAAPYANLAIKAMAXHFKCLKNAITDQL 350
                    578**************************************************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005743.9E-50216348IPR006563POX domain
PfamPF075263.6E-38221347IPR006563POX domain
PROSITE profilePS5007112.179391454IPR001356Homeobox domain
SMARTSM003891.1E-10394458IPR001356Homeobox domain
CDDcd000862.84E-13394455No hitNo description
SuperFamilySSF466895.56E-17396461IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.609.2E-28397458IPR009057Homeodomain-like
PfamPF059201.1E-18411450IPR008422Homeobox KN domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 619 aa     Download sequence    Send to blast
MAEGFEPYHV PQQSRRDKLR VLAGQAQPDC LQPASPSPPP PHLHHALLPL SYDPTTSFIS  60
SSSDLLMCAE PAVKEEGSHH HVINHLMGFA SNSTSSSTFR HNNHHHPYMD PQFPLTLTAV  120
QEINANPFLC PPQDLHPLRD FDHQQPPYDD QVVVFKPEPL SLSLSSSQPT NHTHXTQQTQ  180
NNTNNNSLQR FSSXGINYDS INSGVSVASV PFGPFTGYXS ILKGSRFLKP AQQLLEEFCD  240
VSSREIYSAK VLTAXDSSSF LDPPIESFGD DDSLTAGGDG GQSTRKKSRL ISMLDEVYRR  300
YKQYCQQMQA VARSFEYVAG LGNAAPYANL AIKAMAXHFK CLKNAITDQL HSXNRNGTHL  360
RHEKDENPML HSSRSIYGQR SIHTSEFVDH QPVWRPQRGL PERAVTVLRA WLFEHFLHPY  420
PTDSDKLMLA KQTGLSRSQV SNWFINARVR LWKPMVEEIH MLETRQAQKA SQRVDLSSNR  480
SSDDHLPSPN SLGSENPSTS THRXQDTASK RTRSELHDHI TMGATEQSPS YSNFPSHMHV  540
GHVGMNMAGG SSSGVSLTLG LHQNNGIGFS APFPINAAER FGLGLDGNSE NYAMVGFEAX  600
NRHYGRDVMG GQLLHDFVG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3k2a_A9e-16400458563Homeobox protein Meis2
3k2a_B9e-16400458563Homeobox protein Meis2
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.130500.0fruit
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during late heart stage embryo in the SAM region between the two developing cotyledons. Expression is initially down-regulated in incipient floral primordia but a strong expression is subsequently detected in the central region of young floral primordia and the inner whorl of developing flowers. In fruit, is expressed in the replum of developing ovaries. {ECO:0000269|PubMed:12874117}.
UniprotTISSUE SPECIFICITY: Predominantly expressed in stems, inflorescences and flowers. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989, ECO:0000269|PubMed:15120075, ECO:0000269|PubMed:15155890, ECO:0000269|PubMed:16741748}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008388082.20.0BEL1-like homeodomain protein 9
SwissprotQ9LZM81e-110BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBLA0A498IE990.0A0A498IE99_MALDO; Uncharacterized protein
STRINGXP_008388082.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF28103373
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02030.15e-96TALE family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]
  4. Andrés F, et al.
    Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE.
    Plant Physiol., 2015. 169(3): p. 2187-99
    [PMID:26417007]
  5. Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R
    Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis.
    Dev. Cell, 2016. 39(2): p. 198-208
    [PMID:27666746]
  6. Sehra B,Franks RG
    Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development.
    Front Plant Sci, 2017. 8: p. 1712
    [PMID:29085379]
  7. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]