PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000185288
Common NameWRKY16
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family WRKY
Protein Properties Length: 341aa    MW: 37058.3 Da    PI: 9.6729
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000185288genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY98.83.5e-31273330359
                    -SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
           WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                    D+y+WrKYGqK++kgs++pr+YY+C++  gCp++k+ver+ +dp ++++tYegeH+h 
  MDP0000185288 273 DEYSWRKYGQKPIKGSPYPRGYYKCSTVrGCPARKHVERAPDDPAMLIVTYEGEHRHA 330
                    9************************9888****************************6 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF105334.7E-18216269IPR018872Zn-cluster domain
Gene3DG3DSA:2.20.25.804.5E-32259330IPR003657WRKY domain
PROSITE profilePS5081130.446266332IPR003657WRKY domain
SuperFamilySSF1182903.01E-26269330IPR003657WRKY domain
SMARTSM007742.2E-37271331IPR003657WRKY domain
PfamPF031061.3E-26273329IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0042742Biological Processdefense response to bacterium
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005516Molecular Functioncalmodulin binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 341 aa     Download sequence    Send to blast
MTVELMEFPK MEDQKAIQEA ASQGLQSMEH LIRFLSHQQQ HPNNQSARLD CTDITDHTVS  60
KFKKVISLLN RTGHARFRRG PAQPVQPVHF SSSHPSPSQT LSLAPALNLT PTPAPVPVTA  120
PAVVQQATIE SSFGQSQPHS MTLDFTRPNA FASNPKSAEI EFAKDNFSVS SGSSFMSSAI  180
TGDGSVSNGK LGSSIFLAPA PAVSGAKPPL STAPFKKXCH EHDHSDDTSC KFSASGSASX  240
SGKCHCSKRR KNRVKKTIRV PAISSKIADI PPDEYSWRKY GQKPIKGSPY PRGYYKCSTV  300
RGCPARKHVE RAPDDPAMLI VTYEGEHRHA PESVGLVYES T
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A3e-21259329271WRKY transcription factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.164990.0bud| cell culture| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: In young, mature and senescent leaves. {ECO:0000269|PubMed:11722756}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000, probably by activating the jasmonic acid (JA)- signaling pathway (PubMed:26433201). {ECO:0000250, ECO:0000269|PubMed:26433201}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00464DAPTransfer from AT4G31550Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly during leaf senescence (PubMed:11722756). Repressed by rhizobacterium B.cereus AR156 in leaves, and to a lower extent, by P.fluorescens WCS417r (PubMed:26433201). {ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:26433201}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKJ9960680.0KJ996068.1 Pyrus x bretschneideri WRKY domain class transcription factor (WRKY16) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280840.10.0probable WRKY transcription factor 17
SwissprotQ9SV151e-135WRK11_ARATH; Probable WRKY transcription factor 11
TrEMBLA0A498JEW20.0A0A498JEW2_MALDO; Uncharacterized protein
STRINGXP_008378151.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF13143498
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G31550.21e-115WRKY DNA-binding protein 11
Publications ? help Back to Top
  1. Haas BJ, et al.
    Full-length messenger RNA sequences greatly improve genome annotation.
    Genome Biol., 2002. 3(6): p. RESEARCH0029
    [PMID:12093376]
  2. Brand LH,Kirchler T,Hummel S,Chaban C,Wanke D
    DPI-ELISA: a fast and versatile method to specify the binding of plant transcription factors to DNA in vitro.
    Plant Methods, 2010. 6: p. 25
    [PMID:21108821]
  3. Brand LH, et al.
    Screening for protein-DNA interactions by automatable DNA-protein interaction ELISA.
    PLoS ONE, 2013. 8(10): p. e75177
    [PMID:24146751]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Ali MA,Wieczorek K,Kreil DP,Bohlmann H
    The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots.
    PLoS ONE, 2014. 9(7): p. e102360
    [PMID:25033038]
  6. Jiang CH, et al.
    Transcription factors WRKY70 and WRKY11 served as regulators in rhizobacterium Bacillus cereus AR156-induced systemic resistance to Pseudomonas syringae pv. tomato DC3000 in Arabidopsis.
    J. Exp. Bot., 2016. 67(1): p. 157-74
    [PMID:26433201]
  7. Ali MA, et al.
    Transcription factors WRKY11 and WRKY17 are involved in abiotic stress responses in Arabidopsis.
    J. Plant Physiol., 2018. 226: p. 12-21
    [PMID:29689430]