PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000166587

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

TALE

Protein Properties

Length: 574aa MW: 64038.4 Da PI: 7.0915

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000166587	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	25.7	1.9e-08	493	531	18	54
HHHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS Homeobox 18 lFek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 +F++ ++yp+ +e+ LA k gLt +qV++WF N R + MDP0000166587 493 MFQNflHPYPKDSEKHVLAVKSGLTRNQVSNWFINARVR 531 5887779******************************88 PP
2	BELL	59.1	1.1e-19	360	436	2	71
BELL 2 rqelqkkkakLlslle........eVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeq 71 +qe+++kk+kLl ll+ ++d+ Y+q+ ++++tv+s+F+a+++ ++ ++++++Al++iS +++L+++i+ + MDP0000166587 360 KQEIKAKKTKLLALLQtlilfllmQLDDCYNQCADEIHTVVSAFHAATETDP-HIHARFALQTISVLYKSLRERISAH 436 5899*****998874444444468**********************.********************976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00574	5.9E-20	293	435	IPR006563	POX domain
Pfam	PF07526	5.1E-24	298	434	IPR006563	POX domain
PROSITE profile	PS50071	11.013	472	535	IPR001356	Homeobox domain
CDD	cd00086	8.09E-10	475	536	No hit	No description
SMART	SM00389	4.3E-5	475	539	IPR001356	Homeobox domain
SuperFamily	SSF46689	6.27E-15	477	544	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.0E-25	478	541	IPR009057	Homeodomain-like
Pfam	PF05920	1.7E-14	492	531	IPR008422	Homeobox KN domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 574 aa Download sequence Send to blast
MDNEMYNGRA DGRSSLVMEG VVPHTTMNSL IQSNSFDLDH QNRMMALIPV LSTFQGEPVM 60 DSDSDLIAAN GVSVAEMSPF LTSQRRNNVG DSSFVSSSFA DSTXFQATPQ SSASLAALFA 120 ARGSSLQENL NNLAISAMPI NSSEVYVSND CSNNSNSLFX TAVNCGYDEM LGSINRQWEI 180 NKYSALSELG ERSSVRTGLQ PYSSVGNVDP NGWLSSDGAS VMAYNSYSSS KFSNELALTL 240 ATSRPLDIRK QYPDVGSSGV AXPCLNQTRF XSPEQNSSNS EKLSGSYSSC KPPQLSQVIC 300 GSRYLHVVQE ILSDIANYSL ENLDQSSFSS VRLVSESGMS AMDDGLDGRF EVPKEPAVRK 360 QEIKAKKTKL LALLQTLILF LLMQLDDCYN QCADEIHTVV SAFHAATETD PHIHARFALQ 420 TISVLYKSLR ERISAHFLSI SENSSXASPS ESERSFEIQK QLALQHLKKK EHQIWRPQRG 480 LPERSVSVLR AWMFQNFLHP YPKDSEKHVL AVKSGLTRNQ VSNWFINARV RLWKPMIDEM 540 YSEMNRRKTR QNXNLERNHK SHHIRINTHK FGVN

Sequence ? help Back to Top

Protein Sequence Length: 574 aa Download sequence Send to blast

MDNEMYNGRA DGRSSLVMEG VVPHTTMNSL IQSNSFDLDH QNRMMALIPV LSTFQGEPVM  60
DSDSDLIAAN GVSVAEMSPF LTSQRRNNVG DSSFVSSSFA DSTXFQATPQ SSASLAALFA  120
ARGSSLQENL NNLAISAMPI NSSEVYVSND CSNNSNSLFX TAVNCGYDEM LGSINRQWEI  180
NKYSALSELG ERSSVRTGLQ PYSSVGNVDP NGWLSSDGAS VMAYNSYSSS KFSNELALTL  240
ATSRPLDIRK QYPDVGSSGV AXPCLNQTRF XSPEQNSSNS EKLSGSYSSC KPPQLSQVIC  300
GSRYLHVVQE ILSDIANYSL ENLDQSSFSS VRLVSESGMS AMDDGLDGRF EVPKEPAVRK  360
QEIKAKKTKL LALLQTLILF LLMQLDDCYN QCADEIHTVV SAFHAATETD PHIHARFALQ  420
TISVLYKSLR ERISAHFLSI SENSSXASPS ESERSFEIQK QLALQHLKKK EHQIWRPQRG  480
LPERSVSVLR AWMFQNFLHP YPKDSEKHVL AVKSGLTRNQ VSNWFINARV RLWKPMIDEM  540
YSEMNRRKTR QNXNLERNHK SHHIRINTHK FGVN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4xrs_A	3e-15	481	538	1	58	Homeobox protein Meis1
4xrs_B	3e-15	481	538	1	58	Homeobox protein Meis1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Down-regulated in the shoot apical meristem (SAM) upon floral induction. {ECO:0000269\|PubMed:17908157}.
Uniprot	TISSUE SPECIFICITY: Most abundant in flowers.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor which may be involved in the signal transduction pathway downstream of the COP1 gene. Controls floral competency as a specific activator of FLC expression. Is responsive of the nuclear import of SHOOT MERISTEMLESS (STM). {ECO:0000269\|PubMed:17908157}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By light. In etiolated seedlings, maximally expressed after 3 days of illumination.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028962525.1	0.0	homeobox protein ATH1
Swissprot	P48731	3e-90	ATH1_ARATH; Homeobox protein ATH1
TrEMBL	A0A498JBY4	0.0	A0A498JBY4_MALDO; Uncharacterized protein
STRING	XP_008377518.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF5939	32	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G32980.1	2e-73	homeobox gene 1

Link Out ? help Back to Top
Phytozome	MDP0000166587

Publications ? help Back to Top
Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]