PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000150618
Common NameMdZF1
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family C2H2
Protein Properties Length: 522aa    MW: 57098.4 Da    PI: 8.9811
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000150618genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.32.8e-0597119123
                    EEETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                    ++C++C+k F r  nL+ H r H
  MDP0000150618  97 FVCEICKKGFQRDQNLQLHRRGH 119
                    89*******************88 PP
2zf-C2H214.88.1e-05173195123
                    EEETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                    +kC +C+k +  +s+ k H++t+
  MDP0000150618 173 WKCDKCSKKYAVQSDWKAHLKTC 195
                    58*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.0E-496119IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.09E-796119No hitNo description
SMARTSM003550.03997119IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.63797119IPR007087Zinc finger, C2H2
PROSITE patternPS00028099119IPR007087Zinc finger, C2H2
SMARTSM00355120138168IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.0E-4161194IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.09E-7168193No hitNo description
SMARTSM0035585173193IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 522 aa     Download sequence    Send to blast
MSIITGSAAT GSFSSGNTGG EEVQQQQQEL LNHHANFHGS NSLLPTTPNI NSNGISTTQV  60
QKQPPPAKKK RNLPGTPDPT AEVIALSPKT LMATNRFVCE ICKKGFQRDQ NLQLHRRGHN  120
LPWKLKQRTS TEIIKRVYIC PESSCVHHDP SRALGDLTGI KKHFFRKHGE KTWKCDKCSK  180
KYAVQSDWKA HLKTCGTREY KCDCGTIFSR RDSFITHRAF CDAIAEENNR NQGVVPMSNN  240
IMGAPNQGQL SNSELIIPAS PPMNNKITDN PSSARSDTTT SDQFHHNFDA KNAPLTLEPQ  300
QPFPMPTKPV NMLPRTLSNN TSSSTSPSSL LFGLNHGGHG QSLIPNSSGH LSATQLLQKA  360
AQMGATMSGG PNPNPSGTTI TSMAPSTYGT ATGGYNMNPF MQQRDPNNIL QLETSPQFFG  420
ANYAQMGMFS GMLFDHAQNN GLLKNMEHEN NGTSNKIGFR GASNVSNGDT LTVDFLGLGG  480
SGNNNRPENF HDLQKQQHGQ QDQXGFGGID DHDDHLRMQR FG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C4e-34169240371Zinc finger protein JACKDAW
5b3h_F4e-34169240371Zinc finger protein JACKDAW
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.30050.0fruit| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269|PubMed:25035403}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269|PubMed:25035403}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB1165450.0AB116545.1 Malus x domestica MdZF1 mRNA for zinc finger protein, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028957271.10.0zinc finger protein GAI-ASSOCIATED FACTOR 1-like
SwissprotQ9SCQ61e-110IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBLQ764N70.0Q764N7_MALDO; Zinc finger protein
STRINGXP_009376645.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF21923085
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G50700.11e-106indeterminate(ID)-domain 2
Publications ? help Back to Top
  1. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  3. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]