PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000145898
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family C3H
Protein Properties Length: 562aa    MW: 63714.5 Da    PI: 7.94
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000145898genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH30.56.3e-10475497527
                    --SGGGGTS--TTTTT-SS-SSS CS
        zf-CCCH   5 lCrffartGtCkyGdrCkFaHgp 27 
                     C++f  tG C+yGd+Ck+ H++
  MDP0000145898 475 VCNRFVNTGSCPYGDSCKYLHPK 497
                    5********************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.200.201.8E-2369149No hitNo description
CDDcd14137070374No hitNo description
SuperFamilySSF561127.01E-8474404IPR011009Protein kinase-like domain
PROSITE profilePS5001142.54875371IPR000719Protein kinase domain
PfamPF000695.3E-6075371IPR000719Protein kinase domain
SMARTSM002201.7E-8275371IPR000719Protein kinase domain
PROSITE patternPS00107081105IPR017441Protein kinase, ATP binding site
Gene3DG3DSA:1.10.510.101.6E-57150372No hitNo description
PROSITE patternPS001080196208IPR008271Serine/threonine-protein kinase, active site
SuperFamilySSF902291.06E-6469499IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010314.84470498IPR000571Zinc finger, CCCH-type
SMARTSM003561.4E-5472497IPR000571Zinc finger, CCCH-type
PfamPF006421.2E-7475497IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.103.8E-7475496IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006468Biological Processprotein phosphorylation
GO:0004672Molecular Functionprotein kinase activity
GO:0005524Molecular FunctionATP binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 562 aa     Download sequence    Send to blast
MASVGVAPTS GVREPSGHAV GVDKLPEEMN DMKIRDDKEM ESTVAVVDGN GTEXGHIIVT  60
TIGGRNGQPK QTISYMAERV VGHGSFGVVF QAKCLETGET VAIKKVLQDK RYKNRELQTM  120
RLLDHPNVVS LKHCFFSTTE KDELYLNLVL EYVPETVHRV IKHYNKLNQR MPLIYVKLYT  180
YQIFRALSYI HRCIGVCHRD IKPQNLLVNP HTHQVKLCDF GSAKVLVKGE PNISYICSRY  240
YRAPELIFGA TEYTSAIDVW SVGCVLAELL LGQCNSNTTE FLLHQPLFPG ESGVDQLVEI  300
IKVLGTPTRE EIKCMNPNYT EFKFPQIKAH PWHKIFHKRM PPEAVDLVSR LLQYSPNLRC  360
TALDALVHSF FDDLRDPNTR LPNGRFLPPL FNFKSHVDRP MYRCSVISYF RCNRGKNTGE  420
LETWNLECRW GSIFAITARR NSRTHHLRED AIFKAANTFE PELNDPNHPY PTQGVCNRFV  480
NTGSCPYGDS CKYLHPKNNQ QDTVLIDNNQ SSTFQENQSV GGSSLPDVVV RDHTGTSWSN  540
LPPSLMPPPE GGHPRLPFVD WG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5t31_A1e-1662639620365Glycogen synthase kinase-3 beta
5t31_B1e-1662639620365Glycogen synthase kinase-3 beta
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.16640.0bud| cell culture| flower| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Roots, shoots and leaves.
Functional Description ? help Back to Top
Source Description
UniProtMay mediate extracellular signals to regulate transcription in differentiating cells.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHM2422190.0HM242219.1 Fragaria vesca protein kinase (SK) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008388444.20.0shaggy-related protein kinase alpha
RefseqXP_008388445.20.0shaggy-related protein kinase alpha
RefseqXP_008388446.20.0shaggy-related protein kinase alpha
SwissprotP432880.0KSG1_ARATH; Shaggy-related protein kinase alpha
TrEMBLA0A498IJG80.0A0A498IJG8_MALDO; Uncharacterized protein
STRINGXP_008388444.10.0(Malus domestica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G26749.12e-27C3H family protein
Publications ? help Back to Top
  1. Dornelas MC,Wittich P,von Recklinghausen I,van Lammeren A,Kreis M
    Characterization of three novel members of the Arabidopsis SHAGGY-related protein kinase (ASK) multigene family.
    Plant Mol. Biol., 1999. 39(1): p. 137-47
    [PMID:10080716]
  2. Dornelas MC,Van Lammeren AA,Kreis M
    Arabidopsis thaliana SHAGGY-related protein kinases (AtSK11 and 12) function in perianth and gynoecium development.
    Plant J., 2000. 21(5): p. 419-29
    [PMID:10758494]
  3. Gachon C,Saindrenan P
    Real-time PCR monitoring of fungal development in Arabidopsis thaliana infected by Alternaria brassicicola and Botrytis cinerea.
    Plant Physiol. Biochem., 2004. 42(5): p. 367-71
    [PMID:15191738]
  4. Han L,Mason M,Risseeuw EP,Crosby WL,Somers DE
    Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing.
    Plant J., 2004. 40(2): p. 291-301
    [PMID:15447654]
  5. Langlois-Meurinne M,Gachon CM,Saindrenan P
    Pathogen-responsive expression of glycosyltransferase genes UGT73B3 and UGT73B5 is necessary for resistance to Pseudomonas syringae pv tomato in Arabidopsis.
    Plant Physiol., 2005. 139(4): p. 1890-901
    [PMID:16306146]
  6. Dal Santo S, et al.
    Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.
    Plant Cell, 2012. 24(8): p. 3380-92
    [PMID:22885737]
  7. Zhu JY, et al.
    The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis.
    Mol. Cell, 2017. 66(5): p. 648-657.e4
    [PMID:28575660]
  8. Mittal S, et al.
    Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement.
    Front Chem, 2017. 5: p. 115
    [PMID:29312925]
  9. Huang KC,Lin WC,Cheng WH
    Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis.
    BMC Plant Biol., 2018. 18(1): p. 40
    [PMID:29490615]
  10. Bianchi MW,Guivarc'h D,Thomas M,Woodgett JR,Kreis M
    Arabidopsis homologs of the shaggy and GSK-3 protein kinases: molecular cloning and functional expression in Escherichia coli.
    Mol. Gen. Genet., 1994. 242(3): p. 337-45
    [PMID:7509023]
  11. Dornelas MC,Lejeune B,Dron M,Kreis M
    The Arabidopsis SHAGGY-related protein kinase (ASK) gene family: structure, organization and evolution.
    Gene, 1998. 212(2): p. 249-57
    [PMID:9611268]