PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000142893
Common NameHD6
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HD-ZIP
Protein Properties Length: 761aa    MW: 84558.3 Da    PI: 5.4604
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000142893genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox67.12.3e-21107162156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
       Homeobox   1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                    r+k +++t+eq++e+e+lF+++++p++++r++L+k+lgL  rqVk+WFqNrR++ k
  MDP0000142893 107 RKKYHRHTTEQIREMEALFKESPHPDEKQRQQLSKQLGLAPRQVKFWFQNRRTQIK 162
                    7999************************************************9877 PP
2START228.32.2e-712764992206
                    HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEE CS
          START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetle 83 
                    + ++a++el+k+a+a+ep+Wv+s+    e++n+de++++f  +        +s+ea+r++g+v+ +l++lv++++d++ qW+e+++    ka+t++
  MDP0000142893 276 IVNQAMEELQKMATAGEPLWVRSVetgrEILNYDEYIKEFNIEVPgngrpkRSIEASRETGLVFVDLPRLVQSFMDVN-QWKEMFPcmisKAATVD 370
                    56789***********************************77544999******************************.***************** PP

                    EECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE- CS
          START  84 vissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdl 172
                    vi++g      ga+qlm+aelq+l+plvp R+++fvR+++ql+ ++w+ivdvS+d  +++  ++s+v+++++pSg++ie+k ngh+kv+wveh ++
  MDP0000142893 371 VINNGegddrnGAVQLMFAELQMLTPLVPtREVYFVRCCKQLSPEQWAIVDVSIDKVEDNI-DASLVKCRKRPSGCIIEDKTNGHCKVIWVEHLEC 465
                    ***********************************************************98.9********************************* PP

                    -SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
          START 173 kgrlphwllrslvksglaegaktwvatlqrqcek 206
                    + ++++ ++r +v+sgla+ga++wvatlq qce+
  MDP0000142893 466 QRSTIQTMYRTIVNSGLAFGARHWVATLQLQCER 499
                    ********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.2E-2293158IPR009057Homeodomain-like
SuperFamilySSF466897.52E-2196165IPR009057Homeodomain-like
PROSITE profilePS5007118.269104164IPR001356Homeobox domain
SMARTSM003891.5E-18106168IPR001356Homeobox domain
PfamPF000461.3E-18107162IPR001356Homeobox domain
CDDcd000865.58E-17111162No hitNo description
PROSITE patternPS000270139162IPR017970Homeobox, conserved site
PROSITE profilePS5084839.403266502IPR002913START domain
SuperFamilySSF559615.08E-35269499No hitNo description
CDDcd088751.44E-111271498No hitNo description
Gene3DG3DSA:3.30.530.204.2E-5273493IPR023393START-like domain
SMARTSM002344.6E-72275499IPR002913START domain
PfamPF018523.5E-58276499IPR002913START domain
SuperFamilySSF559614.67E-16528735No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009957Biological Processepidermal cell fate specification
GO:0010062Biological Processnegative regulation of trichoblast fate specification
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 761 aa     Download sequence    Send to blast
MGVDMSNNPP TSRTKDFFAS PALSLSLAGI FRDAGAAASR EVEEGDEGSG GGGSAAVGSV  60
RRREDTTEIS SENSGPGRSR SEDEFDGEGE HDEDDVDGDN KNKKKKRKKY HRHTTEQIRE  120
MEALFKESPH PDEKQRQQLS KQLGLAPRQV KFWFQNRRTQ IKAIQERHEN SLLKGEMEKL  180
RDESKAMREQ INKACCPNCG TATTSRDATL TTEEQQLRIE NARLKSEVEK LRAALVKYPP  240
GTSSPSCSAG QDQENRSSLD FYTGIFGLEE SRIMEIVNQA MEELQKMATA GEPLWVRSVE  300
TGREILNYDE YIKEFNIEVP GNGRPKRSIE ASRETGLVFV DLPRLVQSFM DVNQWKEMFP  360
CMISKAATVD VINNGEGDDR NGAVQLMFAE LQMLTPLVPT REVYFVRCCK QLSPEQWAIV  420
DVSIDKVEDN IDASLVKCRK RPSGCIIEDK TNGHCKVIWV EHLECQRSTI QTMYRTIVNS  480
GLAFGARHWV ATLQLQCERL VFFMATNVPM KDSAGVATLA GRKSILKLAQ RMTASFCRAI  540
GASSYHTWTK ISSKTGDDIR IASRKNSNDP GEPLGVILCA VSSVWLPVSP YLLFDFLRDE  600
TRRNEWDIML NGGPAQTIAN LSKGQDRGNA VTIQSMKSKE NSMWILQDTC INSYESMVVY  660
APVDIPGMQS VMTGCDASNI AILPSGFSIL PDGLESRPMV LTSSQEDRSS EGGTLLTAAF  720
QVLTNSSXTA NKLTMESVES VNTLISCTLR NIKTSLQCED G
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1102107KKKKRK
2102108KKKKRKK
3104108KKRKK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.167200.0bud| fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in developing trichomes.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. {ECO:0000269|PubMed:11844112}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by GEM. {ECO:0000269|PubMed:17450124}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280927.10.0homeobox-leucine zipper protein GLABRA 2-like
SwissprotP466070.0HGL2_ARATH; Homeobox-leucine zipper protein GLABRA 2
TrEMBLD9ZJ210.0D9ZJ21_MALDO; HD domain class transcription factor
STRINGXP_008342675.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF47143352
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G79840.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Wu R,Citovsky V
    Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development.
    Biochem. Biophys. Res. Commun., 2017. 488(3): p. 547-553
    [PMID:28526410]