PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000126587
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family TALE
Protein Properties Length: 345aa    MW: 39161.8 Da    PI: 9.891
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000126587genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox29.99.4e-101391761954
                    HHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS
       Homeobox  19 Fek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 
                    Fe   ++yp+ +++  LAk++gL+ +qV++WF N R +
  MDP0000126587 139 FEHflHPYPTDSDKLMLAKQTGLSRSQVSNWFINARVR 176
                    664459******************************88 PP
2BELL81.98.4e-2723771872
           BELL 18 eVdkrYkqyveqlqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeqi 72
                    V++rYkqy++q+q+v+ sFe vaglg+a+pY++lA ka++rhF+cLk+ai+eq+
  MDP0000126587 23 LVYRRYKQYYQQMQAVARSFEYVAGLGNAAPYANLAIKALARHFKCLKNAITEQL 77
                   589**************************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005742.9E-5175IPR006563POX domain
PfamPF075262.8E-212474IPR006563POX domain
PROSITE profilePS5007112.179117180IPR001356Homeobox domain
SMARTSM003891.1E-10120184IPR001356Homeobox domain
CDDcd000862.57E-12120181No hitNo description
SuperFamilySSF466892.35E-17122187IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.603.9E-28123184IPR009057Homeodomain-like
PfamPF059205.3E-19137176IPR008422Homeobox KN domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 345 aa     Download sequence    Send to blast
MWQAYAVMRE RDGITKSLSD SVLVYRRYKQ YYQQMQAVAR SFEYVAGLGN AAPYANLAIK  60
ALARHFKCLK NAITEQLHFR SRNATHLRHE KDGNPILHSR SANGQRSLHN SEFLEHQPVW  120
RPQRGLPERA VTVLRAWLFE HFLHPYPTDS DKLMLAKQTG LSRSQVSNWF INARVRLWKP  180
MVEEIHMLET RQAQKTSQRV DLSSNRSSDD HLPSPNSLGS ENPSTSTHRV QDTASKRTRR  240
ELHDHITMEA TEQNVSYNNF PSHMHVGHVG MNMAGASSSG VSLTLGLHQN NGNGFSDPFP  300
INAAQRFGLG LDGNGENYAM GGFEAQNRHF ERDVMGGQFL HDFVG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3k2a_A3e-16126184563Homeobox protein Meis2
3k2a_B3e-16126184563Homeobox protein Meis2
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.130500.0fruit
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during late heart stage embryo in the SAM region between the two developing cotyledons. Expression is initially down-regulated in incipient floral primordia but a strong expression is subsequently detected in the central region of young floral primordia and the inner whorl of developing flowers. In fruit, is expressed in the replum of developing ovaries. {ECO:0000269|PubMed:12874117}.
UniprotTISSUE SPECIFICITY: Predominantly expressed in stems, inflorescences and flowers. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269|PubMed:12874117, ECO:0000269|PubMed:12897247, ECO:0000269|PubMed:13678595, ECO:0000269|PubMed:15019989, ECO:0000269|PubMed:15120075, ECO:0000269|PubMed:15155890, ECO:0000269|PubMed:16741748}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009378860.10.0PREDICTED: BEL1-like homeodomain protein 9
RefseqXP_009378869.10.0PREDICTED: BEL1-like homeodomain protein 9
SwissprotQ9LZM88e-85BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBLA0A498K4360.0A0A498K436_MALDO; Uncharacterized protein
STRINGXP_008363517.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF28103373
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02030.12e-77TALE family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]
  4. Andrés F, et al.
    Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE.
    Plant Physiol., 2015. 169(3): p. 2187-99
    [PMID:26417007]
  5. Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R
    Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis.
    Dev. Cell, 2016. 39(2): p. 198-208
    [PMID:27666746]
  6. Sehra B,Franks RG
    Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development.
    Front Plant Sci, 2017. 8: p. 1712
    [PMID:29085379]
  7. Simonini S,Stephenson P,Østergaard L
    A molecular framework controlling style morphology in Brassicaceae.
    Development, 2018.
    [PMID:29440299]