PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000122321

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

C2H2

Protein Properties

Length: 425aa MW: 47304.9 Da PI: 9.3115

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000122321	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.8	2e-05	57	79	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C+k F r nL+ H r H MDP0000122321 57 FVCEVCNKGFQRDQNLQLHRRGH 79 89*******************88 PP
2	zf-C2H2	12.2	0.00055	134	156	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H +++ MDP0000122321 134 WKCEKCSKKYAVQSDWKAHSKVC 156 58*****************9877 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.97E-7	56	79	No hit	No description
Gene3D	G3DSA:3.30.160.60	8.7E-6	56	79	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.97	57	79	IPR007087	Zinc finger, C2H2
Pfam	PF12171	7.8E-5	57	79	IPR022755	Zinc finger, double-stranded RNA binding
SMART	SM00355	0.021	57	79	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	59	79	IPR007087	Zinc finger, C2H2
SMART	SM00355	99	99	129	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.7E-4	122	154	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.97E-7	129	154	No hit	No description
SMART	SM00355	140	134	154	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 425 aa Download sequence Send to blast
MSEDALLVPS TITGFAQEPD SNLNPNPNIN NQFKRKRNPD AEVIAMSPKS LMATNRFVCE 60 VCNKGFQRDQ NLQLHRRGHN LPWKLKQRSK TEVIRKKVYV CPEKTCVHHE PSRALGDLTG 120 IKKHFSRKHG EKKWKCEKCS KKYAVQSDWK AHSKVCGTRE YRCDCGTLFS RKDSFITHRA 180 FCDALAAEQS ARFCSASTIN PSFMNGSITN NAHQPQSIPN FIPMFQSEFA GSDHPAANNS 240 HLSSNAFMPV MLQTASMDMF GPSSSSSQMQ WLINNKKFVE ESSFANANNL SLSSPLIIRG 300 VLKEEEESKG SFSETITTTT TSFYNYNINN NQNHHQQKPM SATALXQKAA RMGSTTSNNP 360 ATTFNDTAFN FNDLVNSMSP SSTQGDTIGD GSLFLSNKHL MMSAGAAAMT KQGQSEQSSL 420 TRDFL

Sequence ? help Back to Top

Protein Sequence Length: 425 aa Download sequence Send to blast

MSEDALLVPS TITGFAQEPD SNLNPNPNIN NQFKRKRNPD AEVIAMSPKS LMATNRFVCE  60
VCNKGFQRDQ NLQLHRRGHN LPWKLKQRSK TEVIRKKVYV CPEKTCVHHE PSRALGDLTG  120
IKKHFSRKHG EKKWKCEKCS KKYAVQSDWK AHSKVCGTRE YRCDCGTLFS RKDSFITHRA  180
FCDALAAEQS ARFCSASTIN PSFMNGSITN NAHQPQSIPN FIPMFQSEFA GSDHPAANNS  240
HLSSNAFMPV MLQTASMDMF GPSSSSSQMQ WLINNKKFVE ESSFANANNL SLSSPLIIRG  300
VLKEEEESKG SFSETITTTT TSFYNYNINN NQNHHQQKPM SATALXQKAA RMGSTTSNNP  360
ATTFNDTAFN FNDLVNSMSP SSTQGDTIGD GSLFLSNKHL MMSAGAAAMT KQGQSEQSSL  420
TRDFL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-34	130	200	3	72	Zinc finger protein JACKDAW
5b3h_F	1e-34	130	200	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	85	96	KQRSKTEVIRKK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.13160	0.0	bud\| fruit\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, especially in vascular initials, cortex, endodermis, and quiescent center (QC). {ECO:0000269\|PubMed:25829440}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that, together with JKD, regulates tissue boundaries and asymmetric cell division in roots by a rapid up-regulation of 'SCARECROW' (SCR), thus controlling the nuclear localization of 'SHORT-ROOT' (SHR) and restricting its action (PubMed:25829440). Confines CYCD6 expression to the cortex-endodermis initial/daughter (CEI/CEID) tissues (PubMed:25829440). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008358430.1	0.0	zinc finger protein BALDIBIS
Refseq	XP_008358437.1	0.0	zinc finger protein BALDIBIS
Refseq	XP_008358444.1	0.0	zinc finger protein BALDIBIS
Refseq	XP_017183477.1	0.0	zinc finger protein BALDIBIS
Swissprot	Q944L3	1e-104	IDD9_ARATH; Zinc finger protein BALDIBIS
TrEMBL	A0A498KB26	0.0	A0A498KB26_MALDO; Uncharacterized protein
STRING	XP_008358430.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF181	34	275

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G45260.1	7e-94	C2H2-like zinc finger protein

Link Out ? help Back to Top
Phytozome	MDP0000122321

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]