PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000060753
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family MIKC_MADS
Protein Properties Length: 197aa    MW: 22478.9 Da    PI: 8.0621
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000060753genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF92.42.1e-29959151
                   S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
         SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                   krien++ rqvtfskRrng+lKKA+ELSvLCdaevaviifs++g++ e+ss
  MDP0000060753  9 KRIENDTSRQVTFSKRRNGLLKKAFELSVLCDAEVAVIIFSQKGRINEFSS 59
                   79***********************************************96 PP
2K-box622.3e-21841701197
          K-box  11 eakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkk 97 
                    e+ +++l++e+a + k+ie L+ +qR+  G++L+ +s++eLq++ +qL +sl +iR++K +l++eq+e+l+ ke+ l +en +L ++
  MDP0000060753  84 EQCMQRLKHESAIMAKKIEILEASQRKHSGNGLDFCSVEELQEISSQLGRSLCSIRERKAQLYMEQLEQLKAKERFLLQENAQLCEE 170
                    566899****************************************************************************99776 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.2E-39160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006631.721161IPR002100Transcription factor, MADS-box
SuperFamilySSF554557.46E-32375IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
CDDcd002655.75E-41372No hitNo description
PRINTSPR004046.8E-30323IPR002100Transcription factor, MADS-box
PfamPF003191.7E-251057IPR002100Transcription factor, MADS-box
PRINTSPR004046.8E-302338IPR002100Transcription factor, MADS-box
PRINTSPR004046.8E-303859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129712.7587177IPR002487Transcription factor, K-box
PfamPF014865.9E-2187171IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 197 aa     Download sequence    Send to blast
MVRGKIEIKR IENDTSRQVT FSKRRNGLLK KAFELSVLCD AEVAVIIFSQ KGRINEFSSS  60
DMHQTIERFH KHVNGGEINM VEVEQCMQRL KHESAIMAKK IEILEASQRK HSGNGLDFCS  120
VEELQEISSQ LGRSLCSIRE RKAQLYMEQL EQLKAKERFL LQENAQLCEE CGAKPLMEFS  180
AQKERAFAPV SCEKAGA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3mu6_A2e-18372271Myocyte-specific enhancer factor 2A
3mu6_B2e-18372271Myocyte-specific enhancer factor 2A
3mu6_C2e-18372271Myocyte-specific enhancer factor 2A
3mu6_D2e-18372271Myocyte-specific enhancer factor 2A
5f28_A2e-18172172MEF2C
5f28_B2e-18172172MEF2C
5f28_C2e-18172172MEF2C
5f28_D2e-18172172MEF2C
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the shoot apical meristem (SAM) during the vegetative phase and the floral transition. After floral transition, expressed in apical meristem (AM), inflorescence meristem (IM) and floral primordia. {ECO:0000269|PubMed:21609362}.
UniprotTISSUE SPECIFICITY: Expressed in quiescent center (QC) cells of root tips (PubMed:18162590, PubMed:21689171). Expressed at the base of the petiole of cotyledons and leaves, in flower buds, petals, sepals and abscission zone of flowers and siliques. {ECO:0000269|PubMed:18162590, ECO:0000269|PubMed:21689171}.
Functional Description ? help Back to Top
Source Description
UniProtMADS-box transcription factor that acts with AGL71 and AGL72 in the control of flowering time. Promotes flowering at the shoot apical and axillary meristems. Seems to act through a gibberellin-dependent pathway. Interacts genetically with SOC1 and its expression is directly regulated by SOC1 (PubMed:21609362). Plays a role in controlling flower organ senescence and abscission by repressing ethylene responses and regulating the expression of BOP2 and IDA (PubMed:21689171). {ECO:0000269|PubMed:21609362, ECO:0000269|PubMed:21689171}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP1640060.0KP164006.1 Pyrus pyrifolia clone PpSOC1-1 SOC1 MADS-box protein mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009371258.11e-110PREDICTED: MADS-box protein AGL42-like
RefseqXP_009371259.11e-110PREDICTED: MADS-box protein AGL42-like
SwissprotQ9FIS12e-66AGL42_ARATH; MADS-box protein AGL42
TrEMBLA0A0D4ZY401e-100A0A0D4ZY40_PYRPY; SOC1 MADS-box protein
STRINGXP_009371258.11e-109(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66630102
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62165.38e-69AGAMOUS-like 42