PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSMUA_Achr6P07100_001
Organism
Musa acuminata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Zingiberales; Musaceae; Musa
Family E2F/DP
Protein Properties Length: 474aa    MW: 52153.3 Da    PI: 4.9302
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSMUA_Achr6P07100_001genomeCIRADView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.11.1e-26147212171
                E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                            r+++sL+llt+kf++ll+++++gi++ln++a++L    v  ++RRiYDi+NVLe+++liekk kn+irwkg
  GSMUA_Achr6P07100_001 147 RYDSSLGLLTKKFINLLKHAHDGILDLNNAAETL---GV--QKRRIYDITNVLEGIGLIEKKLKNKIRWKG 212
                            6899******************************...**..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.6E-29145214IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.17E-17147210IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-34147212IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.5E-24149212IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146607.49E-47223329No hitNo description
SuperFamilySSF1440746.02E-32224329No hitNo description
PfamPF164212.2E-31228327IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 474 aa     Download sequence    Send to blast
MSGGRAAGIR APQPTGQIRQ PPKRHLPFPS TRPPFLAPDE YHRFPGPDGR GIAGDETADA  60
LVIKTPVSFL RKREHEDNEA GESSEWMASP GYAEGLNNLL LTPVSGKGGK TYGRSKIAKY  120
NKSGPHTPMS NAGSPSGNTL TPVGTCRYDS SLGLLTKKFI NLLKHAHDGI LDLNNAAETL  180
GVQKRRIYDI TNVLEGIGLI EKKLKNKIRW KGQDNTRPGE VDDDLSVLQA EVEKLALQEH  240
SLDDRISEMR EKLGVLSEDV NNQKWLYMTE DDIKSLPCFQ NETLIAIKAP HGTTLEVPDP  300
DEAGDYLQRR YRIVLRSTMG PIDVYLVSQF EEKFEEVSGV VTPPKLHSGK SMANPETLGN  360
PTLAVATEES KEKELQVNNQ DSQRGFPDVN SLQDFGSGMM KIVPSDVDTD ADYWLLSDSG  420
FSITDMWKTA PEVQWDGIDV FNTDDFVTGS ASTYQPQTPS SVTDVPSNAN STPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-24142212173PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009403679.10.0PREDICTED: transcription factor E2FB-like isoform X2
SwissprotQ9FV711e-141E2FB_ARATH; Transcription factor E2FB
TrEMBLM0T4V90.0M0T4V9_MUSAM; Uncharacterized protein
STRINGGSMUA_Achr6P07100_0010.0(Musa acuminata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.31e-144E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]