PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10023392
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family LSD
Protein Properties Length: 182aa    MW: 18816.6 Da    PI: 8.3222
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10023392genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD137.92.8e-12730124
      zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdt 24
                 C+gCr +L YPrGA++V+CalC+t
  Lus10023392  7 CSGCRSVLLYPRGASNVCCALCNT 30
                 ***********************8 PP

2zf-LSD149.66.4e-164670125
      zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                 CggCrtlL+Y+rGA+sVRC++C+tV
  Lus10023392 46 CGGCRTLLMYTRGATSVRCSCCHTV 70
                 ************************9 PP

3zf-LSD140.64.1e-1384108125
      zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                  Cg+Crt+L YP GApsV+Ca+C+ V
  Lus10023392  84 CGNCRTMLVYPEGAPSVKCAVCHYV 108
                  **********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010532.0E-12434IPR005735Zinc finger, LSD1-type
PfamPF069431.8E-10730IPR005735Zinc finger, LSD1-type
SuperFamilySSF486956.56E-521107IPR011031Multihaem cytochrome
TIGRFAMsTIGR010531.0E-174372IPR005735Zinc finger, LSD1-type
PfamPF069432.7E-134670IPR005735Zinc finger, LSD1-type
Gene3DG3DSA:3.30.40.109.9E-460110IPR013083Zinc finger, RING/FYVE/PHD-type
TIGRFAMsTIGR010532.7E-1381109IPR005735Zinc finger, LSD1-type
PfamPF069437.1E-1384108IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 182 aa     Download sequence    Send to blast
MQSQLVCSGC RSVLLYPRGA SNVCCALCNT LTAVPAPGLE LAQIICGGCR TLLMYTRGAT  60
SVRCSCCHTV NLAPVSSQIA HINCGNCRTM LVYPEGAPSV KCAVCHYVTD AGMGNGRVQP  120
PVNRPNSAGS AVSYTASSYP PQSPSSQTSQ TQTVVVENPM SVNESGKLVS NVVVGVTTDK  180
K*
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10023392
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012075549.15e-93protein LSD1 isoform X1
RefseqXP_022714636.18e-93vacuolar protein sorting-associated protein 2 homolog 2-like
SwissprotP940778e-69LSD1_ARATH; Protein LSD1
TrEMBLA0A067KSR61e-91A0A067KSR6_JATCU; Uncharacterized protein
STRINGLus100233921e-127(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.71e-69LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]