PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10020804
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family ARF
Protein Properties Length: 1021aa    MW: 114001 Da    PI: 7.0822
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10020804genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.98.1e-23127228199
                  EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefe 91 
                  f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++++ +
  Lus10020804 127 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSIFVSAKRLVAGDSVLFI--WNEKNQ 220
                  99*****************************8544444..48************************************************..888999 PP

                  .EEEEE-S CS
           B3  92 lvvkvfrk 99 
                  l+++++r+
  Lus10020804 221 LLLGIRRA 228
                  9***9986 PP
2Auxin_resp69.11.4e-23253311158
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserr 58 
                  aahaa+t+s F+v++nPras+ eFv++++k++ka++ ++vsvGmRf+m fete+ss rr
  Lus10020804 253 AAHAAATNSCFTVFFNPRASPCEFVISLSKYVKAVYhTRVSVGMRFRMLFETEESSVRR 311
                  79*********************************9789*****************998 PP
3Auxin_resp86.26.4e-293113771883
   Auxin_resp  18 rastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  ras+ eFv++++k++ka++ ++vsvGmRf+m fete+ss rr +Gt++g+sdldpvrWpnS+Wrs+k
  Lus10020804 311 RASPCEFVISLSKYVKAVYhTRVSVGMRFRMLFETEESSVRRHMGTITGISDLDPVRWPNSHWRSVK 377
                  7999**************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019363.27E-49111256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.4E-40120242IPR015300DNA-binding pseudobarrel domain
CDDcd100172.93E-21126227No hitNo description
SMARTSM010192.1E-23127229IPR003340B3 DNA binding domain
PfamPF023624.6E-21127228IPR003340B3 DNA binding domain
PROSITE profilePS5086311.956127229IPR003340B3 DNA binding domain
PfamPF065071.7E-18253311IPR010525Auxin response factor
PfamPF065071.1E-23311377IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 1021 aa     Download sequence    Send to blast
MKLSTSGLSQ QGQEGENKCL NSELWHACAG PLVSLPTVGS RVVYFPQGHS EQVVATTNKE  60
IDGQIPNYPS LPPQLICQLH NLTMHADVET DEVYAQMTLQ PLTEEEQKDT FLPMELGMPS  120
KQPTNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDFSQ QPPAQELIAR DLHDVEWKFR  180
HIFRGQPKRH LLTTGWSIFV SAKRLVAGDS VLFIWNEKNQ LLLGIRRAIR PQTVMPSSVL  240
SSDSMHIGLL AAAAHAAATN SCFTVFFNPR ASPCEFVISL SKYVKAVYHT RVSVGMRFRM  300
LFETEESSVR RASPCEFVIS LSKYVKAVYH TRVSVGMRFR MLFETEESSV RRHMGTITGI  360
SDLDPVRWPN SHWRSVKVGW DESTAGERQP RVSLWEIEPL TTFPMYPSLF PFRLKRPWYP  420
GSSAFPDPRD ENGNSLTWMR GGPGDGLPSM NFQAVNMLPW MQQQRVDPSL LRNDQSQWYQ  480
ALLAASLQSA GNGDPMRQQF MQFQHPLQYQ QQPTTNYPIL QQAPQQSVPH NILSSHNQVS  540
TDSLPQQILQ QQQEPSYNDS IPRQNDQLHG GPSSVHSPNF SKPNFIDSST KFIGGSTVTV  600
QNMLGSLCTE GSGNLLDLTR AVSSSEHLNQ ETWVPKYSHA QVNAFTTPTT HQHQFHDKDH  660
APVPKPGNCS TEALNPNTFG MNIDSTGLLL PTTVPRVATT SSSDPDVLSM PLSVAGFQNS  720
LYSSSEFLPG TGGQVEALNA GPIFVKVYKS GSVGRSLDIS RFSSYHQLRE ELAQMFGIEG  780
KLKNPHRSGW QLDFSADPRD ENGNSLTWMR GGPGDGLPSM NFQAVNMLPW MQQQRVDPSL  840
LRNDQSQWYQ ALLAASLQSA GNGDPMRQQF MQFQHPLQYQ QQPTTNYPIL QQAPQQSVPH  900
NILSSHNQVS TDSLPQQILQ QQQEPSYNDS IPRQNDQLHG GPSSVHSPNF SKPNFIDSST  960
KFIGGSTVTV QNMLGSLCTE GSGNLLDLTR AVSSWHGHCF NWTPLPHHCT ESCYYFFKRS  1020
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1471139841388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10020804
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012074114.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A067KWZ20.0A0A067KWZ2_JATCU; Auxin response factor
STRINGLus100208040.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.20.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]