PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10010969
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family ARF
Protein Properties Length: 793aa    MW: 87801.6 Da    PI: 6.2371
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10010969genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.82.1e-23129230199
                  EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefe 91 
                  f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++++ +
  Lus10010969 129 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI--WNEKNQ 222
                  99*****************************8544444..48************************************************..889999 PP

                  .EEEEE-S CS
           B3  92 lvvkvfrk 99 
                  l+++++r+
  Lus10010969 223 LLLGIRRA 230
                  9****997 PP
2Auxin_resp116.42.4e-38255338183
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  aahaa+t+s F+v+YnPras+ eFv++++k++ka++ +++svGmRf+m fete+ss rr++Gt++g+sdld vrWpnS+Wrs+k
  Lus10010969 255 AAHAAATNSCFTVFYNPRASPCEFVIPLSKYVKAVYhTRISVGMRFRMLFETEESSVRRYMGTITGISDLDAVRWPNSHWRSVK 338
                  79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.96E-49113258IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.106.6E-42122244IPR015300DNA-binding pseudobarrel domain
CDDcd100172.29E-21128229No hitNo description
SMARTSM010191.1E-23129231IPR003340B3 DNA binding domain
PROSITE profilePS5086312.337129231IPR003340B3 DNA binding domain
PfamPF023621.2E-21129230IPR003340B3 DNA binding domain
PfamPF065079.5E-34255338IPR010525Auxin response factor
SuperFamilySSF542772.22E-6665747No hitNo description
PfamPF023094.1E-7670759IPR033389AUX/IAA domain
PROSITE profilePS5174523.873673757IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 793 aa     Download sequence    Send to blast
MKLSTSGLSQ QQSQEGGEKK CLNSELWHAC AGPLVSLPTV GSRVVYFPQG HSEQVVATTN  60
KEVDGHIPNY PNLPAQLICQ LHNVTMHADV ETDEVYAQMT LQPLTPEEQK DTFLPMELGM  120
PSKQPTNYFC KTLTASDTST HGGFSVPRRA AEKVFPPLDF SQQPPAQELI ARDLHDVEWK  180
FRHIFRGQPK RHLLTTGWSV FVSAKRLVAG DSVLFIWNEK NQLLLGIRRA TRPQTVMPSS  240
VLSSDSMHIG LLAAAAHAAA TNSCFTVFYN PRASPCEFVI PLSKYVKAVY HTRISVGMRF  300
RMLFETEESS VRRYMGTITG ISDLDAVRWP NSHWRSVKVG WDESTAGERQ PRVSLWEIEP  360
LTTFPMYPSL FPFRLKRPWH PGSSSFPDSR DENGNNLMWL RGGGAGDGLA PMNFQAVNML  420
PWMQQRVDPS LLRNDNNQWY QAMLAASLQS SGGIGGDPMR QQFMQLQQQP LQYQQQSSIN  480
YPIFTSPSQV PTDGLSQQQI GTQPENHSQQ PEHSYHESLL GGQPSLNSPS FAKTDFVDPN  540
SKFVGSTSTI QNMLGSGNLL DLTRTGQPSS MTQQLNHEPW APHLYPDKDP GTKPGNGGGN  600
EAHSPNNFGM NIESSGLLLP TTVRRVVATT SSSDPDVSSM PLSEPGFQNY LYQQDSSEFL  660
PGTGQLDSIE AGPTFVKVYK SGSVGRSLDI SRFSNYLELR EELAQMFGIE GKLENPHRSG  720
WQLVFVDKEN DVLLLGDGPW ESFVNNVWYI KILSPDDVVK MGQPGVESFS PNPSQRTISS  780
GAPDLASGSF GY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1621235941388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10010969
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012074114.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A067KWZ20.0A0A067KWZ2_JATCU; Auxin response factor
STRINGLus100109690.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]