PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa019285
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ARF
Protein Properties Length: 601aa    MW: 67806.7 Da    PI: 5.3307
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-44261PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B375.56e-24122222198
                EEEE-..-HHHHTT-EE--HHH.HTT.....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEE CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvk 95 
                f+kvlt sd++++g +++ +k+a+e+     + +++ +++l+ +d++g +W++k+i+r++++r++lt+GW+ Fv  ++L +gD++vF   + +++el+v+
  Lsa019285 122 FCKVLTASDTSTHGGFSVLRKHANEClppldMTQPTPTQELVAKDLHGTEWRFKHIFRGQPRRHLLTTGWSTFVTCKRLVAGDSFVFL--RGENGELRVG 219
                99****************************9666677789************************************************..449999**** PP

                EE- CS
         B3  96 vfr 98 
                v+r
  Lsa019285 220 VRR 222
                *98 PP
2Auxin_resp101.61e-33248327183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha+st++ F v+Y+P+  ts+F++ ++k+ +a+++k+svGmRfkm fe+eds+err++Gt+vgv+d++p +W+ SkWrsLk
   Lsa019285 248 ASHAVSTQTRFVVYYKPS--TSQFIIGLNKYIEAINNKFSVGMRFKMPFEGEDSPERRFTGTIVGVEDISP-QWELSKWRSLK 327
                 789**************8..59***********************************************99.*********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.22E-41110251IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.8E-41115237IPR015300DNA-binding pseudobarrel domain
CDDcd100172.17E-21120222No hitNo description
SMARTSM010194.5E-22122224IPR003340B3 DNA binding domain
PROSITE profilePS5086312.125122224IPR003340B3 DNA binding domain
PfamPF023625.9E-22122222IPR003340B3 DNA binding domain
PfamPF065073.6E-31248327IPR010525Auxin response factor
PfamPF023091.4E-6477523IPR033389AUX/IAA domain
PROSITE profilePS5174526.147487568IPR000270PB1 domain
SuperFamilySSF542773.53E-12488563No hitNo description
PfamPF023091.1E-5533571IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 601 aa     Download sequence    Send to blast
MENRESTFLS SEDLLYKELW KACTGPLVDV PRDGERVFYF PQGHMEQLEA STNQELNQRI  60
PLFNLKSKIL CRVVHTQLLA EQETDEVYAQ ITLLPEQNQS DSDPTSPDES LEEPQRPNVH  120
SFCKVLTASD TSTHGGFSVL RKHANECLPP LDMTQPTPTQ ELVAKDLHGT EWRFKHIFRG  180
QPRRHLLTTG WSTFVTCKRL VAGDSFVFLR GENGELRVGV RRFTRQQSSM PSSVISSQSM  240
HLGVLATASH AVSTQTRFVV YYKPSTSQFI IGLNKYIEAI NNKFSVGMRF KMPFEGEDSP  300
ERRFTGTIVG VEDISPQWEL SKWRSLKVEW DEAASITRPE RVSPWEIEPF ATPPPPSIPP  360
TTSLQPPKSK RPRPPEGQMS NFTPPQMDTG WLSSVPSHQE TMKNTNNNND SVELKKVAES  420
ISSCRIFGFD LMIPTNIIPE TQPQPQPASN VYYTLAPSPL SVGTSDLTKE LQVSPKEVQS  480
KQTTCTRSRT KVQMQGMAVG RAVDLTVLNG YDELINELEE MFEIKGQLYP RNQWEIVFTD  540
DEGDMMLMGD DPWQEFCGMV KRILVCSSQD VKKMRVGSSS KLPISYTDNE VSGVSLEAAE  600
N
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1731335017355Auxin response factor 1
4ldw_A1e-1731335017355Auxin response factor 1
4ldw_B1e-1731335017355Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1369373KRPRP
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023750402.10.0auxin response factor 9-like isoform X1
SwissprotQ9ZPY60.0ARFK_ARATH; Auxin response factor 11
TrEMBLA0A2J6M7J80.0A0A2J6M7J8_LACSA; Auxin response factor
STRINGXP_010053162.10.0(Eucalyptus grandis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G23980.20.0auxin response factor 9
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]