PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa019237
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ERF
Protein Properties Length: 229aa    MW: 25915.2 Da    PI: 8.4238
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58679715PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-2516PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP267.62.4e-2182131255
        AP2   2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                +y+G+r+++ +g+W+AeIrdp     +  r++lg+f taeeAa+a+++a+k+++g
  Lsa019237  82 KYRGIRQRP-WGKWAAEIRDPQ----QgVRVWLGTFNTAEEAAQAYDEAAKRIRG 131
                8********.**********94....25*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008478.8E-1582131IPR001471AP2/ERF domain
SuperFamilySSF541712.09E-2282140IPR016177DNA-binding domain
SMARTSM003801.7E-3982145IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.7E-3282139IPR001471AP2/ERF domain
CDDcd000188.68E-3482139No hitNo description
PROSITE profilePS5103224.02682139IPR001471AP2/ERF domain
PRINTSPR003671.0E-118394IPR001471AP2/ERF domain
PRINTSPR003671.0E-11105121IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 229 aa     Download sequence    Send to blast
MCGGAIISDA DAVFNRERKL SADDLWSEFD TSDLFGWDFK PQTLLSTTEV AIKNKTISKH  60
KKIFNEEKSQ PIEKKPKARK NKYRGIRQRP WGKWAAEIRD PQQGVRVWLG TFNTAEEAAQ  120
AYDEAAKRIR GGKAKLNFPL PPAKKLRTES TQSTVHVPPS PRPPTLLSYD QFQKQSYYSN  180
SVADEHEFKE QISNLETFLG LDHELTQFGG LGGESAGDVW TLDDFPVII
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A1e-2378140164ATERF1
3gcc_A1e-2378140164ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:9159183}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269|PubMed:18836139, ECO:0000269|PubMed:9159183}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023768721.11e-170ethylene-responsive transcription factor RAP2-3-like
SwissprotP427365e-52RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBLA0A2J6L3031e-169A0A2J6L303_LACSA; Uncharacterized protein
STRINGGorai.011G193600.12e-61(Gossypium raimondii)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16770.12e-46ethylene-responsive element binding protein
Publications ? help Back to Top
  1. Bueso E, et al.
    The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene.
    Plant J., 2007. 52(6): p. 1052-65
    [PMID:17931347]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Chen YC, et al.
    Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance.
    Sci Rep, 2014. 4: p. 5584
    [PMID:24998294]
  4. Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB
    Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis.
    New Phytol., 2015. 208(2): p. 442-55
    [PMID:25988998]
  5. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  6. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  7. Liu W, et al.
    Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency.
    Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868
    [PMID:28390898]
  8. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]