PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa018688
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ARF
Protein Properties Length: 748aa    MW: 84434.8 Da    PI: 6.4789
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58695356PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.11.6e-23113214199
                EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EE CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvv 94 
                f+k+lt sd++++g +++ +++a+e+      + + + +++l+ +d++g +W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + +++el+v
  Lsa018688 113 FCKTLTASDTSTHGGFSVLRRHADEClppldmSRQ-PPTQELVAKDLHGSEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGENGELRV 209
                99*****************************7333.34459************************************************..449999*** PP

                EEE-S CS
         B3  95 kvfrk 99 
                +v+r+
  Lsa018688 210 GVRRA 214
                **996 PP
2Auxin_resp112.24.9e-37239321183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha++t+++F+v+Y+Pr+s+seF+v+++++++++k+++s+GmRf m+fe+e+++e+r++Gt+vg+++ ++ rWp+SkWr Lk
   Lsa018688 239 AWHAIQTGTMFTVYYKPRTSPSEFIVPFDQYMESVKNNYSIGMRFNMRFEGEEAPEQRFTGTIVGIEEREQQRWPDSKWRYLK 321
                 89******************************************************************************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.57E-40109242IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.3E-41109228IPR015300DNA-binding pseudobarrel domain
CDDcd100172.38E-21111213No hitNo description
PfamPF023622.0E-21113214IPR003340B3 DNA binding domain
SMARTSM010196.4E-23113215IPR003340B3 DNA binding domain
PROSITE profilePS5086311.942113215IPR003340B3 DNA binding domain
PfamPF065075.4E-35239321IPR010525Auxin response factor
PfamPF023091.2E-10598715IPR033389AUX/IAA domain
SuperFamilySSF542779.32E-12628707No hitNo description
PROSITE profilePS5174522.582630714IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 748 aa     Download sequence    Send to blast
ADADIALYKD LWRACAGPLV TVPRENELVF YFPQGHIEQV EASTNQVADQ QMPVYNLPAK  60
ILCRVVNVQL KAEPDTDEVF AQITLMPEPN QDENVVKKEP PPPPESQFRV HSFCKTLTAS  120
DTSTHGGFSV LRRHADECLP PLDMSRQPPT QELVAKDLHG SEWRFRHIFR GQPRRHLLQS  180
GWSVFVSSKR LVAGDAFIFL RGENGELRVG VRRAMRQQPN IPSSVISSHS MHLGVLATAW  240
HAIQTGTMFT VYYKPRTSPS EFIVPFDQYM ESVKNNYSIG MRFNMRFEGE EAPEQRFTGT  300
IVGIEEREQQ RWPDSKWRYL KVRWDESSTI PRPERVSPWK IEPALVPPAI NPLPVHRQKR  360
PRSTMLPSSP DSSVLTREGP SKMGTADPSP AFSRVLQGQE LSTLRPTFVD SNESDSCDRL  420
IQWAPSVVDD EKRHHGSDRI LSVGRTPESS FTDLLSGFGS TNELSTTPAP TPNESKFNLH  480
SNPWSIMPSG LSLSLLGGGM KSNEISYQSR DVRFSAFDEY SGQHSQRGNG EQAGKWVMPP  540
PSLTSYLQMP SHSSDVNVKP KDGNCKIFGV PLAGNRNISA DAAATHQYHI FDSDQSKRLK  600
VIDHNPSKEQ DKEYQHFQQA KLQGVSVSSR SCTKVHKQGI ALGRSVDLTK FNDYDELIAE  660
LDVIFEFNGE LKTRNKNWLV VYTDDEGDMM LVGDDPWQEF CGMVRKIFIY TREEVQRMNP  720
GTLNSRDEDN SSVAEGMDEK DTRKIENA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-179634318354Auxin response factor 1
4ldw_A1e-179634318354Auxin response factor 1
4ldw_B1e-179634318354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor. Involved in the control of fruit ripening process. Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26716451, PubMed:26959229). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression is up-regulated by plant hormone auxin in tomato fruits. {ECO:0000269|PubMed:26716451}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023757978.10.0auxin response factor 2B-like isoform X1
SwissprotK4DF010.0ARF2B_SOLLC; Auxin response factor 2B
TrEMBLA0A2J6MH570.0A0A2J6MH57_LACSA; Auxin response factor
STRINGVIT_17s0000g00320.t010.0(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]