PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa016093
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family NF-X1
Protein Properties Length: 862aa    MW: 96837.9 Da    PI: 8.5179
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58695838PU_unrefUnigeneView CDS
PUT-187a-Lactuca_sativa-37786PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X118.93.4e-06180198120
   zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                CG HkC  lCH+GpCp+Cp+
  Lsa016093 180 CG-HKCLLLCHPGPCPSCPK 198
                **.***************96 PP
2zf-NF-X118.16e-06394413120
   zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                CG+H C++ C+ G+CppC++
  Lsa016093 394 CGRHACKRRCCDGDCPPCSE 413
                ******************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF578503.53E-672141No hitNo description
PROSITE patternPS01359073134IPR019786Zinc finger, PHD-type, conserved site
PROSITE profilePS500899.12673135IPR001841Zinc finger, RING-type
CDDcd060081.20E-5168216No hitNo description
PfamPF014220.0014180197IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0073180198IPR000967Zinc finger, NF-X1-type
CDDcd060087.19E-8222270No hitNo description
SMARTSM004387232251IPR000967Zinc finger, NF-X1-type
PfamPF0142254234250IPR000967Zinc finger, NF-X1-type
CDDcd060081.60E-8275315No hitNo description
PfamPF014220.039285303IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0017285304IPR000967Zinc finger, NF-X1-type
CDDcd060081.26E-4329372No hitNo description
SMARTSM004380.12339359IPR000967Zinc finger, NF-X1-type
PfamPF0142215341358IPR000967Zinc finger, NF-X1-type
CDDcd060081.55E-8384432No hitNo description
PfamPF014228.3E-4394412IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0092394413IPR000967Zinc finger, NF-X1-type
CDDcd060085.56E-11411459No hitNo description
PfamPF014220.015421439IPR000967Zinc finger, NF-X1-type
SMARTSM004380.015421440IPR000967Zinc finger, NF-X1-type
SMARTSM0043837478499IPR000967Zinc finger, NF-X1-type
PfamPF014224.7488498IPR000967Zinc finger, NF-X1-type
PfamPF0142248507516IPR000967Zinc finger, NF-X1-type
SMARTSM0043847507552IPR000967Zinc finger, NF-X1-type
PfamPF014220.2589599IPR000967Zinc finger, NF-X1-type
SMARTSM004383.7589616IPR000967Zinc finger, NF-X1-type
CDDcd060081.40E-4614655No hitNo description
SMARTSM004380.0095626644IPR000967Zinc finger, NF-X1-type
PfamPF014220.22628643IPR000967Zinc finger, NF-X1-type
SMARTSM0043812689710IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 862 aa     Download sequence    Send to blast
MTSTVRHRLP PSHPSDSDSS DSDSTSTTPK PLNHTDFSNT IFRSYVEISG LESPDLTKIR  60
SFLTSSRSGA LSCLICLERI RPTDPTWSCS SRCFAVFHLL CIQSWARQSS DLSSLRAAAR  120
GADDRNSTWN CPKCRIEFPK TLIPKTYTCF CGKFENPPHD PWILPHSCGE ICNRSLKYDC  180
GHKCLLLCHP GPCPSCPKLV KTRCFCGGVE DTKRCGFKDF SCNKTCSKLL DCKTHCCPET  240
CHPGGCPPCK ATGVYNCHCG KATEKRECFQ RDFRCETPCE KLLGCGKHVC SKGCHEGECG  300
DCPLQGKRTC PCGKRIYEGM ACDVVVPSCG GTCDKKLMCR IHSCPERCHR GLCVESCRIV  360
VMKSCKCGSL KKQNRFLVXQ DVVCERKCQR VRDCGRHACK RRCCDGDCPP CSEICDKKLR  420
CKNHKCPSPC HRGACAPCPV MVTISCFCGE THFEVPCGTE KEQKPPKCSK RCQITPLCRH  480
KSITKPHKCH YGACPPCRLV CDEEYPCGHR CKLKCHGPIP PPNPEFTLKP KKKKQKLQTE  540
TTPGSSCPPC PELVWRSCLG QHLGAEKMMV CSNKSKFSCD NYCGNLLPCG NHFCTKTCHA  600
LKIPGSGGEQ CEDCNLPCQR ERDPLCPHPC PRKCHPGDCP PCKVLIKRSC HCGAMVHVFE  660
CLYYNTLSEK EQTAVRSCGG PCHKKLPNCT HLCPETCHIG HCPSPEKCSK KVIVRCGCQS  720
LKKEWACHQV QATYINNGRD PKDITKNQFG VGLLPCNSEC KSKLKVDDPD LHLRKPKAPE  780
KKETDVENHV RKRKRRKEKL QQDLQLSMFQ KVMGIFWKLL VLVMIVVSLI LMAYFGYKGL  840
LWVNDWMNEV EIQRQRKRYP RM
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1790795RKRKRR
2790796RKRKRRK
3790797RKRKRRKE
4791796KRKRRK
5792797RKRRKE
6792798RKRRKEK
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023752902.10.0NF-X1-type zinc finger protein NFXL2
SwissprotQ9FFK80.0NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A2J6M2B90.0A0A2J6M2B9_LACSA; Uncharacterized protein
STRINGVIT_13s0067g00920.t010.0(Vitis vinifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.10.0sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors