PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa014883

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

FAR1

Protein Properties

Length: 845aa MW: 97254.7 Da PI: 6.9761

Description

FAR1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58696102	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-25409	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	FAR1	87.7	1.8e-27	87	190	1	91
FAR1 1 kfYneYAkevGFsvrkskskkskrngeitkrtfvCskegkreeekkk.............tekerrtraetrtgCkaklkvkkekdgkwevtkleleHnH 87 +fY+eYA+++GFs+ +++s++sk+++e+++++f Cs++g+++e++k+ e+++ +r+ ++t+Cka+++vk++ dgkw ++++e+eHnH Lsa014883 87 SFYQEYARSMGFSTAIQNSRRSKTSREFIDAKFACSRYGTKREHDKSfnrphgrnrtnqdPENASGRRSCSKTDCKASMHVKRRPDGKWIIHRFEKEHNH 186 5*******************************************9**9998776666667999***************************** PP FAR1 88 elap 91 el p Lsa014883 187 ELLP 190 *975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03101	1.2E-25	87	190	IPR004330	FAR1 DNA binding domain
Pfam	PF10551	2.1E-28	288	380	IPR018289	MULE transposase domain
PROSITE profile	PS50966	9.446	566	604	IPR007527	Zinc finger, SWIM-type
Pfam	PF04434	5.9E-4	577	601	IPR007527	Zinc finger, SWIM-type
SMART	SM00575	3.2E-8	579	606	IPR006564	Zinc finger, PMZ-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 845 aa Download sequence Send to blast
MDIDLRLPSG DHENEEKEEE AKEMSNMIDA EHKIHNEEFL SIRDKSPPDN DIGLNSPSLD 60 MAEYKEDDIN LEPIAGMEFE SHGEAYSFYQ EYARSMGFST AIQNSRRSKT SREFIDAKFA 120 CSRYGTKREH DKSFNRPHGR NRTNQDPENA SGRRSCSKTD CKASMHVKRR PDGKWIIHRF 180 EKEHNHELLP AQAVSEQTRK MYAAMARQFA EYKNVVGLKN DSSNPFDKTR NTALEAGEAN 240 ILCKFFVHMQ SINSNFFYAI DVGEDQRVKN MLWADAKTRH DYVNFCDVVS FDTSYVKNKY 300 KMPLALFIGV NQHYQFMLLG CALLSDESSA TYSWVMQTWL AAMGGRVPKV VITDKDHNLE 360 SSVAQIFPSS KHCFCLWNIM GKISEALNHV IKEHDNFMVK FEKCIHRSWT DDQFEKRWFK 420 IIERFGLKDY DWMQSLYETR KQWVPIYMKD VCLAGMSTPQ RSESVNCFFD KYVHRKTSVQ 480 EFIRQYETII QDRYEEEAKG DSDTWNKPPT LRSPSPFEKH VSSIYTHAVF KKFQVEVLGA 540 VACMPKKEAQ EEMVATFRVS DFEKNMDFNV SYNEPTSEVT CICRLFEFKG FLCRHAMIVL 600 QICGLSSIPA QYILKRWTKD VKNRGLTLMS EGGEQLQYRV QRYNDLCQRA IKLGEEGSLS 660 QESYNLAIGA LEEVYTNCVC LNNSNKNLIE VGTSSGQGVL RIEDDNQRNT RANKKKNPMK 720 KRKANSEQDI MTVGGQDSLQ QLDKLSSRSI GLDGYFGPQQ SMQGMVQLNL MAPSRDNYYG 780 NQQAIQGLGQ LNSIAPNHEC YYGAQPTLHS LGQMDFLRAP GFTYGIREEP SVRTTQLHDD 840 GSRHA

Sequence ? help Back to Top

Protein Sequence Length: 845 aa Download sequence Send to blast

MDIDLRLPSG DHENEEKEEE AKEMSNMIDA EHKIHNEEFL SIRDKSPPDN DIGLNSPSLD  60
MAEYKEDDIN LEPIAGMEFE SHGEAYSFYQ EYARSMGFST AIQNSRRSKT SREFIDAKFA  120
CSRYGTKREH DKSFNRPHGR NRTNQDPENA SGRRSCSKTD CKASMHVKRR PDGKWIIHRF  180
EKEHNHELLP AQAVSEQTRK MYAAMARQFA EYKNVVGLKN DSSNPFDKTR NTALEAGEAN  240
ILCKFFVHMQ SINSNFFYAI DVGEDQRVKN MLWADAKTRH DYVNFCDVVS FDTSYVKNKY  300
KMPLALFIGV NQHYQFMLLG CALLSDESSA TYSWVMQTWL AAMGGRVPKV VITDKDHNLE  360
SSVAQIFPSS KHCFCLWNIM GKISEALNHV IKEHDNFMVK FEKCIHRSWT DDQFEKRWFK  420
IIERFGLKDY DWMQSLYETR KQWVPIYMKD VCLAGMSTPQ RSESVNCFFD KYVHRKTSVQ  480
EFIRQYETII QDRYEEEAKG DSDTWNKPPT LRSPSPFEKH VSSIYTHAVF KKFQVEVLGA  540
VACMPKKEAQ EEMVATFRVS DFEKNMDFNV SYNEPTSEVT CICRLFEFKG FLCRHAMIVL  600
QICGLSSIPA QYILKRWTKD VKNRGLTLMS EGGEQLQYRV QRYNDLCQRA IKLGEEGSLS  660
QESYNLAIGA LEEVYTNCVC LNNSNKNLIE VGTSSGQGVL RIEDDNQRNT RANKKKNPMK  720
KRKANSEQDI MTVGGQDSLQ QLDKLSSRSI GLDGYFGPQQ SMQGMVQLNL MAPSRDNYYG  780
NQQAIQGLGQ LNSIAPNHEC YYGAQPTLHS LGQMDFLRAP GFTYGIREEP SVRTTQLHDD  840
GSRHA

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CACGCGC-3'. Activates the expression of FHY1 and FHL involved in light responses. When associated with PHYA, protects it from being recognized and degraded by the COP1/SPA complex. Positive regulator of chlorophyll biosynthesis via the activation of HEMB1 gene expression. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:12753585, ECO:0000269\|PubMed:17012604, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:18715961, ECO:0000269\|PubMed:22634759}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated after exposure to far-red light. Subject to a negative feedback regulation by PHYA signaling. Up-regulated by white light. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:22634759}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023736891.1	0.0	protein FAR-RED ELONGATED HYPOCOTYL 3 isoform X2
Swissprot	Q9LIE5	0.0	FHY3_ARATH; Protein FAR-RED ELONGATED HYPOCOTYL 3
TrEMBL	A0A2J6K8M2	0.0	A0A2J6K8M2_LACSA; Uncharacterized protein
STRING	XP_009804946.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G22170.2	0.0	far-red elongated hypocotyls 3

Publications ? help Back to Top
Chang N,Gao Y,Zhao L,Liu X,Gao H Arabidopsis FHY3/CPD45 regulates far-red light signaling and chloroplast division in parallel. Sci Rep, 2015. 5: p. 9612 [PMID:25872642] Wang C, et al. SCAB3 Is Required for Reorganization of Actin Filaments during Light Quality Changes. J Genet Genomics, 2015. 42(4): p. 161-8 [PMID:25953354] Wang W, et al. A pair of light signaling factors FHY3 and FAR1 regulates plant immunity by modulating chlorophyll biosynthesis. J Integr Plant Biol, 2016. 58(1): p. 91-103 [PMID:25989254] Ma L, et al. Arabidopsis FHY3 and FAR1 Regulate Light-Induced myo-Inositol Biosynthesis and Oxidative Stress Responses by Transcriptional Activation of MIPS1. Mol Plant, 2016. 9(4): p. 541-57 [PMID:26714049] Siddiqui H,Khan S,Rhodes BM,Devlin PF FHY3 and FAR1 Act Downstream of Light Stable Phytochromes. Front Plant Sci, 2016. 7: p. 175 [PMID:26941752] Li D, et al. FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9375-80 [PMID:27469166] Liu L,Li B,Liu X FAR-RED ELONGATED HYPOCOTYL3 promotes floral meristem determinacy in Arabidopsis. Plant Signal Behav, 2016. 11(10): p. e1238545 [PMID:27660915] Ma L,Xue N,Fu X,Zhang H,Li G Arabidopsis thaliana FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1) modulate starch synthesis in response to light and sugar. New Phytol., 2017. 213(4): p. 1682-1696 [PMID:27859295] Liu Y, et al. Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1. Plant Cell, 2017. 29(9): p. 2269-2284 [PMID:28842534] Joly-Lopez Z, et al. Abiotic Stress Phenotypes Are Associated with Conserved Genes Derived from Transposable Elements. Front Plant Sci, 2017. 8: p. 2027 [PMID:29250089]