PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||||||
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TF ID | Lsa013747 | ||||||||||||
Organism | |||||||||||||
Taxonomic ID | |||||||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
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Family | AP2 | ||||||||||||
Protein Properties | Length: 515aa MW: 56823 Da PI: 6.6782 | ||||||||||||
Description | AP2 family protein | ||||||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 53.4 | 6.6e-17 | 184 | 233 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g Lsa013747 184 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 233 78*******************......55************************997 PP | |||||||
2 | AP2 | 42.9 | 1.2e-13 | 276 | 326 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g Lsa013747 276 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEVEAARAYDKAAIKCNG 326 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SuperFamily | SSF54171 | 3.01E-15 | 184 | 241 | IPR016177 | DNA-binding domain |
Pfam | PF00847 | 6.0E-9 | 184 | 233 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 5.57E-11 | 185 | 240 | No hit | No description |
Gene3D | G3DSA:3.30.730.10 | 1.1E-16 | 185 | 240 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 17.411 | 185 | 241 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 2.3E-31 | 185 | 247 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 3.86E-17 | 276 | 335 | IPR016177 | DNA-binding domain |
CDD | cd00018 | 4.42E-25 | 276 | 336 | No hit | No description |
Pfam | PF00847 | 3.4E-9 | 276 | 326 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 1.3E-16 | 277 | 335 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 15.672 | 277 | 334 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 2.1E-32 | 277 | 340 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 4.4E-6 | 278 | 289 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 4.4E-6 | 316 | 336 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 515 aa Download sequence Send to blast |
MWDLNGSPDR RRRDEDEGEG CSSAPVVGEE EYNNIKGKRV GGSVSNSSSS IIVVDQDDGS 60 DVDEDSDAGG LQKLTTTGDS RLFGFSMADN SSWDYNPPVT HQFFPLDDSE VGSTTFVGAG 120 RETTSLPTTY PTSNWFGVKF SHPSSEPSCF SGGVAGGNNG FSGKVTDVPQ PLKKSRRGPR 180 SRSSQYRGVT FYRRTGRWES HIWDCGKQVY LGGFDTAHAA ARAYDRAAIK FRGVEADINF 240 ILQDYEDDLK QTSNLTKEEF VHVLRRQSTG FPRGSSKYRG VTLHKCGRWE ARMGQFLGKK 300 YVYLGLFDTE VEAARAYDKA AIKCNGKDAV TNFDSSTYEN ELNSTECTNN NDKIINETSS 360 DHNLDLSLGG GSTSNKPRNI EFRDYHQIPS NSIQFGFSRP PASGSGWFDG GRREGYNETE 420 TFQLLSQTHL QSPPGSFMGY SEGRGYGHFI RPANPTMLHT FNPTSFNSLT NHQMQFTSST 480 AHGGGSNPSP HQMYANSAAA SSGFPQQRFH FRQPP |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 8 | 13 | DRRRRD |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_023754311.1 | 0.0 | floral homeotic protein APETALA 2-like | ||||
Swissprot | P47927 | 1e-122 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A2J6LZ81 | 0.0 | A0A2J6LZ81_LACSA; Uncharacterized protein | ||||
STRING | cassava4.1_005852m | 1e-155 | (Manihot esculenta) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-112 | AP2 family protein |