PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa013079
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ARR-B
Protein Properties Length: 679aa    MW: 73850 Da    PI: 6.395
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-187a-Lactuca_sativa-28959PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.38.2e-29228281155
    G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  Lsa013079 228 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 281
                79*******************.********************************8 PP
2Response_reg80.46e-27531611109
                   EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS
  Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 
                   vl+vdD+p+ +++l+++l++ +y ev+ +  +e al  l+e++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a ++++ + + +  Ga 
     Lsa013079  53 VLVVDDDPTCLKILEKMLRNCNY-EVTKCNRAEVALSHLRENKngFDVVISDVHMPDMDGFKLLEHIGIEM-DLPVIMMSADDSKSVVMKGVTHGAC 147
                   89*********************.***************999999**********************6644.8************************ PP

                   EEEESS--HHHHHH CS
  Response_reg  96 dflsKpfdpeelvk 109
                   d+l Kp+ +e+l++
     Lsa013079 148 DYLIKPVRIEALRN 161
                   ***********987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363921.2E-17130674IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23004.4E-4350187No hitNo description
SuperFamilySSF521722.42E-3650174IPR011006CheY-like superfamily
SMARTSM004484.5E-3151163IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.84252167IPR001789Signal transduction response regulator, receiver domain
PfamPF000723.9E-2453161IPR001789Signal transduction response regulator, receiver domain
CDDcd001563.80E-2754166No hitNo description
PROSITE profilePS5129410.896225284IPR017930Myb domain
SuperFamilySSF466895.2E-20226285IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.4E-30227286IPR009057Homeodomain-like
TIGRFAMsTIGR015579.7E-25228281IPR006447Myb domain, plants
PfamPF002499.8E-8230280IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 679 aa     Download sequence    Send to blast
MNLGGGQVVN KQSMMPSSSG ASWKSTTGGG VSGGGGGGGD GGVPDQFPAG LRVLVVDDDP  60
TCLKILEKML RNCNYEVTKC NRAEVALSHL RENKNGFDVV ISDVHMPDMD GFKLLEHIGI  120
EMDLPVIMMS ADDSKSVVMK GVTHGACDYL IKPVRIEALR NIWQHVVRKR KHEWKEFEPS  180
ASADEQKPPE EPDYSSSANE GHNWKNTKRR KDEDDEADER DDSSSLKKPR VVWSVELHQQ  240
FVAAVNQLGI DKAVPKKILE LMNVPGLTRE NVASHLQKYR LYLRRLSGSQ HPGGLSTGFM  300
GSPEAGYGSI SSLNGLDLQA LAASGQLGQL PPQSLATLQA AALGRSNNSK SPISVPVIDQ  360
RNIFSFENPK RYTEVQSQHL TNNNNTNKQM NLLPGIPTNM EPKQFVSLHQ SGQHSFGSMN  420
NQVLIQMGGQ NQNQNQNQSQ SQGHGHGQSI PNAIPHHGMR QQPVLSSEML TRGGVVDLAT  480
TTVYNPVVSQ ASSLVDFSMN HKTDSSGNSY PIGGSLGISN ITSSSSTLQG DGSLDSKVSR  540
RGIVPSYDIF NDLNQNGYRD WGLQDVGLTF DQSPPVLLQH SRSSGQEMGG QNCNLTTTGT  600
HRNGSNIGQP RNAYVGENSL RVKAESFNDG SSHNNLYPEQ YGQDDLLAAI LKQQQQQESV  660
GQPENEFGFD GYALDNLPV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A7e-23224287164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023766807.10.0two-component response regulator ARR2-like isoform X3
SwissprotQ9ZWJ91e-179ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A2J6L7A60.0A0A2J6L7A6_LACSA; Two-component response regulator
STRINGXP_002519174.10.0(Ricinus communis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-162response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]