PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lsa010658
Organism
Lactuca sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca
Family ARF
Protein Properties Length: 532aa    MW: 60335.9 Da    PI: 6.9018
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Lsa#S58693485PU_refUnigeneView CDS
PUT-187a-Lactuca_sativa-32438PU_unrefplantGDBView CDS
PUT-187a-Lactuca_sativa-32439PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B378.75.9e-25110210198
                EEEE-..-HHHHTT-EE--HHH.HTT.....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEE CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvk 95 
                f+kvlt sd++++g +++ +k+a+e+     +++++ +++l+ +d++g +W++k+i+r++++r++lt+GW+ Fv a++L +gD++vF   + +++el+v+
  Lsa010658 110 FCKVLTASDTSTHGGFSVLRKHANEClpaldMSQPTPTQELVAKDLHGTEWRFKHIFRGQPRRHLLTTGWSTFVTAKRLVAGDSFVFL--RGENGELRVG 207
                99****************************977777888*************************************************..4499999**9 PP

                EE- CS
         B3  96 vfr 98 
                v r
  Lsa010658 208 VKR 210
                976 PP
2Auxin_resp99.35.4e-33236315183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha+st++ F v+Y+Pr+  s+F++ ++k+ +++++k+s+GmRf m+fe eds+err++G+++gv+dl+  +W+ S+WrsLk
   Lsa010658 236 ASHAVSTQTRFVVYYKPRT--SQFIIGLNKYIESVNNKFSIGMRFNMRFECEDSPERRFTGMITGVEDLSH-QWECSQWRSLK 315
                 789***************6..9**********************************************766.*********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.22E-3996239IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.3E-39104225IPR015300DNA-binding pseudobarrel domain
CDDcd100172.79E-21108210No hitNo description
PfamPF023624.5E-23110210IPR003340B3 DNA binding domain
SMARTSM010193.3E-23110212IPR003340B3 DNA binding domain
PROSITE profilePS5086312.337110212IPR003340B3 DNA binding domain
PfamPF065071.4E-30236315IPR010525Auxin response factor
PfamPF023091.3E-6413455IPR033389AUX/IAA domain
PROSITE profilePS5174523.518419500IPR000270PB1 domain
SuperFamilySSF542772.16E-12420495No hitNo description
PfamPF023092.5E-6462500IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 532 aa     Download sequence    Send to blast
MEDLLYKELW KACAGPLVDV PRDGERVFYF PQGHMEQLEE SNNQEIDQSI PHFNLKSKIL  60
CRVVYTQLLA EQDTDEVYAQ ITLLPEADQS DPTSLDKCID DPPKASIHSF CKVLTASDTS  120
THGGFSVLRK HANECLPALD MSQPTPTQEL VAKDLHGTEW RFKHIFRGQP RRHLLTTGWS  180
TFVTAKRLVA GDSFVFLRGE NGELRVGVKR VGQQHNSMPS SVISSRSMRL GVLATASHAV  240
STQTRFVVYY KPRTSQFIIG LNKYIESVNN KFSIGMRFNM RFECEDSPER RFTGMITGVE  300
DLSHQWECSQ WRSLKVQWVE PTSIVRPDRV SPWEIETETH ATTFIPTSSG QPVGVGVGPN  360
KTKRPRPPVN LPLPNVDLLK KSENVSTCRL FGFDLKIVVP SVERHEPDQK DCKQTGLTRT  420
RTKVQMQGVA VGRAVDLTML KGYNHLIDEL EEMFEIKGKL RSKSQWEIVF TDDEGDMMLM  480
GDDPWQEFCK MVKRILICSC QDVKKMSCGS KLQLSSYLDN ELSGFSLEAA EH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-167133615353Auxin response factor 1
4ldw_A1e-167133615353Auxin response factor 1
4ldw_B1e-167133615353Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1362366KRPRP
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023764748.10.0auxin response factor 18-like isoform X1
SwissprotQ9C5W90.0ARFR_ARATH; Auxin response factor 18
SwissprotQ9ZPY60.0ARFK_ARATH; Auxin response factor 11
TrEMBLA0A2J6MFM80.0A0A2J6MFM8_LACSA; Auxin response factor
STRINGPOPTR_0001s10900.10.0(Populus trichocarpa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G61830.10.0auxin response factor 18
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]