PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa010230

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

CAMTA

Protein Properties

Length: 1059aa MW: 119300 Da PI: 5.8099

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-8188	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	179.7	3.5e-56	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrcywl 101 l+ ++rwl++ ei++iL n++k+++++e+ +rp++gsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+++vl+cyYah+e+n++fqrr+ywl Lsa010230 20 LEAQHRWLRPAEICEILRNYTKFRIASEPGNRPPNGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEDNENFQRRSYWL 119 5679********************************************************************************************** PP CG-1 102 Leeelekivlvhylevk 118 Leeel++ivlvhy+evk Lsa010230 120 LEEELSNIVLVHYREVK 136 ************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	81.403	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	2.5E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	8.7E-49	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:1.25.40.20	3.3E-16	87	108	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF81296	2.18E-16	484	569	IPR014756	Immunoglobulin E-set
Gene3D	G3DSA:2.60.40.10	3.6E-4	484	559	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	1.5E-4	484	557	IPR002909	IPT domain
CDD	cd00204	4.15E-12	668	770	No hit	No description
SuperFamily	SSF48403	7.31E-15	670	771	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	3.3E-16	673	770	IPR020683	Ankyrin repeat-containing domain
PROSITE profile	PS50297	16.68	679	764	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	5.7E-7	684	765	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.0082	712	741	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.885	712	744	IPR002110	Ankyrin repeat
SMART	SM00248	700	751	780	IPR002110	Ankyrin repeat
SMART	SM00015	30	879	901	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.565	880	909	IPR000048	IQ motif, EF-hand binding site
SuperFamily	SSF52540	2.52E-7	882	930	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Pfam	PF00612	0.18	882	900	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	1.7E-4	902	924	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.816	903	927	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	1.1E-4	905	924	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1059 aa Download sequence Send to blast
MAEARRYALA AQLDIDQILL EAQHRWLRPA EICEILRNYT KFRIASEPGN RPPNGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEDNE NFQRRSYWLL 120 EEELSNIVLV HYREVKGSRT NTNRVREVGE ATPNSLESEE NISSSEVDSS VSSKFRTFNY 180 PVASQTTENS TQASEYEDAE SAYSHQSTSR YGSILNLQPK TDDQLSMPYY PAPPSNDYDA 240 KFQVNPDMSF VSLMQGGKID NNPDAGFTYK PQKNLDMPAW DNDFEGYQST HLSTQPYNPN 300 ILTHGNEMPR QIMPDGSNKM QEFRGNPGWQ LDGPYNVPSR FQEELSYAEI FKAFESNDTI 360 DHNNPLITQI NMESHVTNED GGRHLQPNLE SNPNPSVDEK PGSLKSPFLE GFKKEGIKKL 420 DSFDRWMSKE LGDVKESQTQ STSGTYWEAV ESENGVDDSI ISPQVHLDTY VLGPSLSQDQ 480 LFSIIDFSPN WAYAGSEIKV LVTGRFLRSQ QELQHCEWAC MFGELEVPAE VVADGVLRCY 540 TPGHKSGRVH FYVTCSNRVA CSEVREFEFK VNENLSQDMD GVQDINADNS NGTLLHMRFV 600 KLLSLGPETA RNSARSVVDP ELLNQLSRLI QEDDREWEQY PSEKAQNQLL ERLLKEKLYA 660 WLIHKVGEGG KGPSVLDEGG QGVLHFAAAL GYDWAIPATV AAGVSINFRD VNGWTALHWA 720 ASCGRERTVA FLISEGALAG ALTDPSPTYP SGRTPADLAS ANGDKGIAGY CAEAALSTHL 780 EQLKLKDRDS KAKAVQTVSE RTPTPPGYGD RPQGLSLKDS LAAVCNATQA AARIHQVFRV 840 QSFQKKQMKG GEFEMTEERA VSMALKSSRM GGQHDEPVHA AAAAVRIQNK FRSWKGRKDF 900 LMMRQRIVKI QAHVRGHQVR KNYKKIVWSV GILDKVILRW RRKGSGLRGF KPEPVAEGST 960 STTTTVAKSG KEEDDDFFKE GRKQTEQRLQ KALARVKSMV QYPEARDQYR RLLNVVNDMQ 1020 ESKAVYDKAL ESSEEAIDFD EDLIDLDALL DDDDAFMNI

Sequence ? help Back to Top

Protein Sequence Length: 1059 aa Download sequence Send to blast

MAEARRYALA AQLDIDQILL EAQHRWLRPA EICEILRNYT KFRIASEPGN RPPNGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEDNE NFQRRSYWLL  120
EEELSNIVLV HYREVKGSRT NTNRVREVGE ATPNSLESEE NISSSEVDSS VSSKFRTFNY  180
PVASQTTENS TQASEYEDAE SAYSHQSTSR YGSILNLQPK TDDQLSMPYY PAPPSNDYDA  240
KFQVNPDMSF VSLMQGGKID NNPDAGFTYK PQKNLDMPAW DNDFEGYQST HLSTQPYNPN  300
ILTHGNEMPR QIMPDGSNKM QEFRGNPGWQ LDGPYNVPSR FQEELSYAEI FKAFESNDTI  360
DHNNPLITQI NMESHVTNED GGRHLQPNLE SNPNPSVDEK PGSLKSPFLE GFKKEGIKKL  420
DSFDRWMSKE LGDVKESQTQ STSGTYWEAV ESENGVDDSI ISPQVHLDTY VLGPSLSQDQ  480
LFSIIDFSPN WAYAGSEIKV LVTGRFLRSQ QELQHCEWAC MFGELEVPAE VVADGVLRCY  540
TPGHKSGRVH FYVTCSNRVA CSEVREFEFK VNENLSQDMD GVQDINADNS NGTLLHMRFV  600
KLLSLGPETA RNSARSVVDP ELLNQLSRLI QEDDREWEQY PSEKAQNQLL ERLLKEKLYA  660
WLIHKVGEGG KGPSVLDEGG QGVLHFAAAL GYDWAIPATV AAGVSINFRD VNGWTALHWA  720
ASCGRERTVA FLISEGALAG ALTDPSPTYP SGRTPADLAS ANGDKGIAGY CAEAALSTHL  780
EQLKLKDRDS KAKAVQTVSE RTPTPPGYGD RPQGLSLKDS LAAVCNATQA AARIHQVFRV  840
QSFQKKQMKG GEFEMTEERA VSMALKSSRM GGQHDEPVHA AAAAVRIQNK FRSWKGRKDF  900
LMMRQRIVKI QAHVRGHQVR KNYKKIVWSV GILDKVILRW RRKGSGLRGF KPEPVAEGST  960
STTTTVAKSG KEEDDDFFKE GRKQTEQRLQ KALARVKSMV QYPEARDQYR RLLNVVNDMQ  1020
ESKAVYDKAL ESSEEAIDFD EDLIDLDALL DDDDAFMNI

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023763264.1	0.0	calmodulin-binding transcription activator 3
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A2J6LEZ3	0.0	A0A2J6LEZ3_LACSA; Uncharacterized protein
STRING	XP_006428204.1	0.0	(Citrus clementina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]