PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa010199

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

NAC

Protein Properties

Length: 300aa MW: 34716.9 Da PI: 6.2938

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-187a-Lactuca_sativa-5657	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	162.8	1.2e-50	10	138	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.kgel 99 lppGfrF P+deelv++yL kk++++++ ++ e+d++++ePw+Lp+++k +++ewyfFs rd+kyatg r+nrat sgyWkatgkd++v+++ +g+ Lsa010199 10 LPPGFRFYPSDEELVCHYLYKKIANEDVLK-GTLVEIDLHTCEPWQLPEMAKLNSSEWYFFSFRDRKYATGYRTNRATISGYWKATGKDRTVVDTrTGAI 108 79**********************9655.78***********88888999*********************************9867888 PP NAM 100 vglkktLvfykgrapkgektdWvmheyrle 129 vg++ktLvfyk+rap+g kt W+mhe+rle Lsa010199 109 VGMRKTLVFYKNRAPNGIKTGWIMHEFRLE 138 *************************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	5.49E-61	8	156	IPR003441	NAC domain
PROSITE profile	PS51005	58.324	10	156	IPR003441	NAC domain
Pfam	PF02365	1.6E-27	11	137	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 300 aa Download sequence Send to blast
MGLRDIGATL PPGFRFYPSD EELVCHYLYK KIANEDVLKG TLVEIDLHTC EPWQLPEMAK 60 LNSSEWYFFS FRDRKYATGY RTNRATISGY WKATGKDRTV VDTRTGAIVG MRKTLVFYKN 120 RAPNGIKTGW IMHEFRLENP NIPPKEDWVL CRVFYKAKGD NSNERSPQDM YHNTCDATSL 180 NHDDACPTLP PPPCVHHHHH ICTTTPNLSN QNPTPPVHHH RHHKNYLDIS PQQYNLPNLL 240 QLSQEATLKE CMDQMIVSSN SKCEDHYGFF YDMALEDYAP SQNLQDMEFD DDDNDNGIVF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	5e-48	9	156	16	165	NO APICAL MERISTEM PROTEIN
1ut4_B	5e-48	9	156	16	165	NO APICAL MERISTEM PROTEIN
1ut7_A	5e-48	9	156	16	165	NO APICAL MERISTEM PROTEIN
1ut7_B	5e-48	9	156	16	165	NO APICAL MERISTEM PROTEIN
4dul_A	5e-48	9	156	16	165	NAC domain-containing protein 19
4dul_B	5e-48	9	156	16	165	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for axillary meristem initiation and separation of the meristem from the main stem. May act as an inhibitor of cell division. {ECO:0000269\|PubMed:12837947, ECO:0000269\|PubMed:17122068}.
UniProt	Transcriptional activator that mediates auxin signaling to promote lateral root development. Activates the expression of two downstream auxin-responsive genes, DBP and AIR3. {ECO:0000269\|PubMed:11114891}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By BRM, at the chromatin level, and conferring a very specific spatial expression pattern. {ECO:0000269\|PubMed:16854978}.
UniProt	INDUCTION: Induced by auxin.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023733505.1	0.0	protein CUP-SHAPED COTYLEDON 3-like
Swissprot	Q84TE6	3e-61	NAC22_ARATH; NAC domain-containing protein 21/22
Swissprot	Q9S851	4e-61	NAC31_ARATH; Protein CUP-SHAPED COTYLEDON 3
TrEMBL	A0A2J6KGM3	0.0	A0A2J6KGM3_LACSA; Uncharacterized protein
STRING	EOX94424	1e-121	(Theobroma cacao)
STRING	XP_009624737.1	1e-120	(Nicotiana tomentosiformis)

Publications ? help Back to Top
Le Hénanff G, et al. Grapevine NAC1 transcription factor as a convergent node in developmental processes, abiotic stresses, and necrotrophic/biotrophic pathogen tolerance. J. Exp. Bot., 2013. 64(16): p. 4877-93 [PMID:24043850] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen C, et al. Transcriptome profiling reveals roles of meristem regulators and polarity genes during fruit trichome development in cucumber (Cucumis sativus L.). J. Exp. Bot., 2014. 65(17): p. 4943-58 [PMID:24962999] Gonçalves B, et al. A conserved role for CUP-SHAPED COTYLEDON genes during ovule development. Plant J., 2015. 83(4): p. 732-42 [PMID:26119568] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Huo X,Wang C,Teng Y,Liu X Identification of miRNAs associated with dark-induced senescence in Arabidopsis. BMC Plant Biol., 2015. 15: p. 266 [PMID:26530097] Chen X, et al. Auxin-Independent NAC Pathway Acts in Response to Explant-Specific Wounding and Promotes Root Tip Emergence during de Novo Root Organogenesis in Arabidopsis. Plant Physiol., 2016. 170(4): p. 2136-45 [PMID:26850273] Balkunde R,Kitagawa M,Xu XM,Wang J,Jackson D SHOOT MERISTEMLESS trafficking controls axillary meristem formation, meristem size and organ boundaries in Arabidopsis. Plant J., 2017. 90(3): p. 435-446 [PMID:28161901] Espinosa-Ruiz A, et al. TOPLESS mediates brassinosteroid control of shoot boundaries and root meristem development in Arabidopsis thaliana. Development, 2017. 144(9): p. 1619-1628 [PMID:28320734] Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Liu C,Wang B,Li Z,Peng Z,Zhang J TsNAC1 Is a Key Transcription Factor in Abiotic Stress Resistance and Growth. Plant Physiol., 2018. 176(1): p. 742-756 [PMID:29122985]