PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa005721

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

MYB

Protein Properties

Length: 322aa MW: 35965.9 Da PI: 7.0789

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58687453	PU_ref	Unigene	View CDS
PUT-187a-Lactuca_sativa-29620	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	58.7	1.3e-18	13	60	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEde+lv+ ++++G +W++ +r g++R++k+c++rw +yl Lsa005721 13 KGPWTPEEDEKLVNHIQKHGHSSWRALPRLAGLNRCGKSCRLRWTNYL 60 79********************************************97 PP
2	Myb_DNA-binding	50.9	3.6e-16	66	111	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+++ eE++ +++++ +lG++ W++Ia ++ gRt++++k++w+++l Lsa005721 66 RGKFSHEEEQTILHLHSMLGNK-WSAIATRLS-GRTDNEIKNYWNTHL 111 89******************.*****.**********996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	8.8E-25	5	63	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.003	8	60	IPR017930	Myb domain
SuperFamily	SSF46689	8.59E-31	10	107	IPR009057	Homeodomain-like
SMART	SM00717	5.1E-15	12	62	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-16	13	60	IPR001005	SANT/Myb domain
CDD	cd00167	5.14E-12	15	60	No hit	No description
PROSITE profile	PS51294	26.322	61	115	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	2.5E-26	64	116	IPR009057	Homeodomain-like
SMART	SM00717	7.5E-15	65	113	IPR001005	SANT/Myb domain
Pfam	PF00249	2.8E-15	66	111	IPR001005	SANT/Myb domain
CDD	cd00167	1.14E-10	68	111	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 322 aa Download sequence Send to blast
MGRPPCDESG LKKGPWTPEE DEKLVNHIQK HGHSSWRALP RLAGLNRCGK SCRLRWTNYL 60 RPDIKRGKFS HEEEQTILHL HSMLGNKWSA IATRLSGRTD NEIKNYWNTH LKKKLIQMGI 120 DPMTHRPCTD IFASLPQLMA LANLKELVEH HSSISWPSNS SSLEQQLSMI AKLQTEQAVH 180 QIAKIQYLNN LLQCTPPLPL HTGLISHPPN MEDLNYLGLY NGSSSSVGIS NFDDDLNLPF 240 SHLPNLQPPE NIVHSCSDDA WVSSRCSSPA AVVVPVAPPV TSMTNSTSDD ACSSPTTSRC 300 GKAPPQFWPD LLLEDPLFHD IL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gv2_A	9e-28	11	115	2	105	MYB PROTO-ONCOGENE PROTEIN
1h8a_C	1e-27	11	115	25	128	MYB TRANSFORMING PROTEIN
1mse_C	9e-28	11	115	2	105	C-Myb DNA-Binding Domain
1msf_C	9e-28	11	115	2	105	C-Myb DNA-Binding Domain
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as negative regulator of lateral root (LR) development. Required for normal auxin responses during LR development. May be part of a negative feedback loop stimulated specifically in the endodermis upon LR initiation to ensure that LRs are formed only in the correct place. {ECO:0000269\|PubMed:24902892}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA), auxin and gravity in roots. {ECO:0000269\|PubMed:24902892}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023745891.1	0.0	myb-related protein 308-like
Swissprot	Q9S9Z2	4e-93	MYB93_ARATH; Transcription factor MYB93
TrEMBL	A0A2J6JPB2	0.0	A0A2J6JPB2_LACSA; Uncharacterized protein
STRING	POPTR_0007s05360.1	1e-108	(Populus trichocarpa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34670.1	6e-95	myb domain protein 93

Publications ? help Back to Top
Gibbs DJ,Coates JC AtMYB93 is an endodermis-specific transcriptional regulator of lateral root development in arabidopsis. Plant Signal Behav, 2014. 9(10): p. e970406 [PMID:25482809]